Search Results - "Gilbert, Lawrence I"

The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis by Rewitz, Kim F., Yamanaka, Naoki, Gilbert, Lawrence I., O'Connor, Michael B.

“…Holometabolous insects undergo complete metamorphosis to become sexually mature adults. Metamorphosis is initiated by brain-derived prothoracicotropic hormone…”
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Prothoracicotropic Hormone Regulates Developmental Timing and Body Size in Drosophila by McBrayer, Zofeyah, Ono, Hajime, Shimell, MaryJane, Parvy, Jean-Philippe, Beckstead, Robert B., Warren, James T., Thummel, Carl S., Dauphin-Villemant, Chantal, Gilbert, Lawrence I., O'Connor, Michael B.

“…In insects, control of body size is intimately linked to nutritional quality as well as environmental and genetic cues that regulate the timing of…”
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Insect Neuropeptide Bursicon Homodimers Induce Innate Immune and Stress Genes during Molting by Activating the NF-κB Transcription Factor Relish by An, Shiheng, Dong, Shengzhang, Wang, Qian, Li, Sheng, Gilbert, Lawrence I, Stanley, David, Song, Qisheng, Aballay, Alejandro

“…Bursicon is a heterodimer neuropeptide composed of two cystine knot proteins, bursicon α (burs α) and bursicon β (burs β), that elicits cuticle tanning…”
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Accessory gland as a site for prothoracicotropic hormone controlled ecdysone synthesis in adult male insects by Hentze, Julie L, Moeller, Morten E, Jørgensen, Anne F, Bengtsson, Meghan S, Bordoy, Anna M, Warren, James T, Gilbert, Lawrence I, Andersen, Ole, Rewitz, Kim F

“…Insect steroid hormones (ecdysteroids) are important for female reproduction in many insect species and are required for the initiation and coordination of…”
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MET is required for the maximal action of 20-hydroxyecdysone during Bombyx metamorphosis by Guo, Enen, He, Qianyu, Liu, Shumin, Tian, Ling, Sheng, Zhentao, Peng, Qin, Guan, Jingmin, Shi, Mingan, Li, Kang, Gilbert, Lawrence I, Wang, Jian, Cao, Yang, Li, Sheng

“…Little is known about how the putative juvenile hormone (JH) receptor, the bHLH-PAS transcription factor MET, is involved in 20-hydroxyecdysone (20E; the…”
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Spook and Spookier code for stage-specific components of the ecdysone biosynthetic pathway in Diptera by Ono, Hajime, Rewitz, Kim F., Shinoda, Tetsuro, Itoyama, Kyo, Petryk, Anna, Rybczynski, Robert, Jarcho, Michael, Warren, James T., Marqués, Guillermo, Shimell, Mary Jane, Gilbert, Lawrence I., O'Connor, Michael B.

“…Ecdysteroids regulate many key developmental events in arthropods including molting and metamorphosis. Recently, members of the Drosophila Halloween group of…”
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Daphnia Halloween genes that encode cytochrome P450s mediating the synthesis of the arthropod molting hormone: evolutionary implications by Rewitz, Kim F, Gilbert, Lawrence I

“…In crustaceans and insects, development and reproduction are controlled by the steroid hormone, 20-hydroxyecdysone (20E). Like other steroids, 20E, is…”
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Drosophila Niemann-Pick Type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative disease by Huang, Xun, Warren, James T, Buchanan, Joann, Gilbert, Lawrence I, Scott, Matthew P

“…Mutations in either of the two human Niemann-Pick type C (NPC) genes, NPC1 and NPC2 , cause a fatal neurodegenerative disease associated with abnormal…”
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CONTROL AND BIOCHEMICAL NATURE OF THE ECDYSTEROIDOGENIC PATHWAY by Gilbert, Lawrence I, Rybczynski, Robert, Warren, James T

“…Molting is elicited by a critical titer of ecdysteroids that includes the principal molting hormone, 20-hydroxyecdysone (20E), and ecdysone (E), which is the…”
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Juvenile hormone counteracts the bHLH-PAS transcription factors MET and GCE to prevent caspase-dependent programmed cell death in Drosophila by Liu, Ying, Sheng, Zhentao, Liu, Hanhan, Wen, Di, He, Qianyu, Wang, Sheng, Shao, Wei, Jiang, Rong-Jing, An, Shiheng, Sun, Yaning, Bendena, William G, Wang, Jian, Gilbert, Lawrence I, Wilson, Thomas G, Song, Qisheng, Li, Sheng

“…Juvenile hormone (JH) regulates many developmental and physiological events in insects, but its molecular mechanism remains conjectural. Here we report that…”
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Molecular evolution of the insect Halloween family of cytochrome P450s: Phylogeny, gene organization and functional conservation by Rewitz, Kim F., O’Connor, Michael B., Gilbert, Lawrence I.

“…The insect molting hormone, 20-hydroxyecdysone (20E), is a major modulator of the developmental processes resulting in molting and metamorphosis. During…”
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New players in the regulation of ecdysone biosynthesis by Huang, Xun, Warren, James T., Gilbert, Lawrence I.

“…Insect ecdysone steroid hormone regulates major developmental transitions, such as molting and metamorphosis. The production of ecdysone correlates well with…”
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Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone by Petryk, A, Warren, J.T, Marques, G, Jarcho, M.P, Gilbert, L.I, Kahler, J, Parvy, J.P, Li, Y, Dauphin-Villemant, C, O'Connor, M.B

“…The steroid 20-hydroxyecdysone (20E) is the primary regulatory hormone that mediates developmental transitions in insects and other arthropods. 20E is produced…”
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Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis by Warren, James T., Petryk, Anna, Marqués, Guillermo, Parvy, Jean-Philippe, Shinoda, Tetsuro, Itoyama, Kyo, Kobayashi, Jun, Jarcho, Michael, Li, Yutai, O’Connor, Michael B., Dauphin-Villemant, Chantal, Gilbert, Lawrence I.

“…We have reported recently the identification and characterization of the last three mitochondrial cytochrome P450 enzymes (CYP) controlling the biosynthesis of…”
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A phosphoproteomics approach to elucidate neuropeptide signal transduction controlling insect metamorphosis by Rewitz, Kim F., Larsen, Martin R., Lobner-Olesen, Anders, Rybczynski, Robert, O'Connor, Michael B., Gilbert, Lawrence I.

“…In insects, the neuropeptide prothoracicotropic hormone (PTTH) stimulates production of ecdysone (E) in the prothoracic glands (PGs). E is the precursor of the…”
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The juvenile hormones: historical facts and speculations on future research directions by Gilbert, Lawrence I, A. Granger, Noelle, Roe, R.Michael

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A Molecular Genetic Approach to the Biosynthesis of the Insect Steroid Molting Hormone by Gilbert, Lawrence I., Warren, James T.

“…Insect growth, development, and molting depend upon a critical titer of the principal molting hormone of arthropods, 20‐hydroxyecdysone (20E). Although the…”
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Identification, characterization and developmental expression of Halloween genes encoding P450 enzymes mediating ecdysone biosynthesis in the tobacco hornworm, Manduca sexta by Rewitz, Kim F., Rybczynski, Robert, Warren, James T., Gilbert, Lawrence I.

“…The insect molting hormone 20-hydroxyecdysone (20E) plays a central role in regulating gene expression during development and metamorphosis. In many…”
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Global identification of bursicon-regulated genes in Drosophila melanogaster by An, Shiheng, Wang, Songjie, Gilbert, Lawrence I, Beerntsen, Brenda, Ellersieck, Mark, Song, Qisheng

“…Bursicon is a heterodimer neuropeptide responsible for regulating cuticle sclerotization and wing expansion in several insect species. Recent studies indicate…”
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Germline-dependent gene expression in distant non-gonadal somatic tissues of Drosophila by Parisi, Michael J, Gupta, Vaijayanti, Sturgill, David, Warren, James T, Jallon, Jean-Marc, Malone, John H, Zhang, Yu, Gilbert, Lawrence I, Oliver, Brian

“…Drosophila females commit tremendous resources to egg production and males produce some of the longest sperm in the animal kingdom. We know little about the…”
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