Search Results - "Gilbert, David"
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Control of DNA replication timing in the 3D genome
Published in Nature reviews. Molecular cell biology (01-12-2019)“…The 3D organization of mammalian chromatin was described more than 30 years ago by visualizing sites of DNA synthesis at different times during the S phase of…”
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Measuring Tourists’ Emotional Experiences toward Hedonic Holiday Destinations
Published in Journal of travel research (01-11-2010)“…Destinations are more likely to be successful if they recognize the experiential qualities of their offerings. However, with some exceptions, research into the…”
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3
Replication licensing during S phase: breaking the law to prevent breaking DNA
Published in Nature structural & molecular biology (01-04-2023)“…A cardinal rule of DNA replication is to prevent any possibility of pre-replication complexes re-loading during S phase, risking genotoxic over-replication…”
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The Future of Antibiotics and Resistance
Published in The New England journal of medicine (24-01-2013)“…Antibiotic resistance and the collapse of the antibiotic research-and-development pipeline continue to worsen despite our ongoing efforts. If we're to develop…”
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Shutting Down the Machines of Destruction: Possibilities for Agrarian Life on the Protest Blockade
Published in Antipode (01-09-2023)“…The protest blockade is one tool for seeking liberation from the state while living within it. I offer a critical analysis of the protest blockade in agrarian…”
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Evaluating genome-scale approaches to eukaryotic DNA replication
Published in Nature reviews. Genetics (01-10-2010)“…Key Points Mechanisms regulating where and when eukaryotic DNA replication initiates remain a fundamental mystery in molecular biology. Genome-scale approaches…”
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Single-cell replication profiling to measure stochastic variation in mammalian replication timing
Published in Nature communications (30-01-2018)“…Mammalian DNA replication is regulated via multi-replicon segments that replicate in a defined temporal order during S-phase. Further, early/late replication…”
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Neglected Variables in the Interpretation of Serum Procalcitonin Levels in Patients With Septic Shock
Published in The Journal of infectious diseases (21-07-2020)“…The interpretation of serum procalcitonin (PCT) levels in septic patients is facilitated by reviewing the known stimuli that activate the PCT family of genes…”
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Procalcitonin as a Biomarker in Respiratory Tract Infection
Published in Clinical infectious diseases (01-05-2011)“…Serum procalcitonin (PCT) levels rapidly increase in patients with invasive bacterial disease. PCT levels increase faster than do C-reactive protein levels…”
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An integrated education programme for NDT professionals
Published in E-journal of Nondestructive Testing (01-08-2023)“…Some years ago, the British Institute of Non-Destructive Testing (BINDT) began work on a programme to integrate vocational qualification – for example…”
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Seven Ways to Preserve the Miracle of Antibiotics
Published in Clinical infectious diseases (15-05-2013)“…Antibiotic resistance is a well-acknowledged crisis with no clearly defined comprehensive, national corrective plan. We propose a number of interventions that,…”
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Replicating Large Genomes: Divide and Conquer
Published in Molecular cell (02-06-2016)“…Complete duplication of large metazoan chromosomes requires thousands of potential initiation sites, only a small fraction of which are selected in each cell…”
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High-resolution Repli-Seq defines the temporal choreography of initiation, elongation and termination of replication in mammalian cells
Published in Genome Biology (24-03-2020)“…DNA replication in mammalian cells occurs in a defined temporal order during S phase, known as the replication timing (RT) programme. Replication timing is…”
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Use of Plasma Procalcitonin Levels as an Adjunct to Clinical Microbiology
Published in Journal of Clinical Microbiology (01-07-2010)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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DNA replication timing
Published in Cold Spring Harbor perspectives in biology (01-08-2013)“…Patterns of replication within eukaryotic genomes correlate with gene expression, chromatin structure, and genome evolution. Recent advances in genome-scale…”
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Replication timing and transcriptional control: beyond cause and effect — part III
Published in Current opinion in cell biology (01-06-2016)“…DNA replication is essential for faithful transmission of genetic information and is intimately tied to chromosome structure and function. Genome duplication…”
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The Future of Antibiotics and Resistance: A Tribute to a Career of Leadership by John Bartlett
Published in Clinical infectious diseases (15-09-2014)“…The ways we have developed, used, and protected antibiotics have led, predictably, to our current crisis of rising antibiotic resistance and declining new…”
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Infectious Diseases Society of America (IDSA) POSITION STATEMENT: Why IDSA Did Not Endorse the Surviving Sepsis Campaign Guidelines
Published in Clinical infectious diseases (02-05-2018)“…IDSA did not endorse the 2016 Surviving Sepsis Campaign Guidelines despite being represented in the working group that drafted the guidelines document…”
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Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation
Published in PLoS pathogens (01-04-2012)“…Primary human hepatocytes isolated from patient biopsies represent the most physiologically relevant cell culture model for hepatitis C virus (HCV) infection,…”
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Nebulized Antibiotics for Multidrug-Resistant Ventilator-Associated Pseudomonas aeruginosa Pneumonia
Published in Critical care medicine (01-06-2019)Get full text
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