Search Results - "Gil Lozano, Manuel"

The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes by Giroud, Maude, Kotschi, Stefan, Kwon, Yun, Le Thuc, Ophélia, Hoffmann, Anne, Gil‐Lozano, Manuel, Karbiener, Michael, Higareda‐Almaraz, Juan Carlos, Khani, Sajjad, Tews, Daniel, Fischer‐Posovszky, Pamela, Sun, Wenfei, Dong, Hua, Ghosh, Adhideb, Wolfrum, Christian, Wabitsch, Martin, Virtanen, Kirsi A, Blüher, Matthias, Nielsen, Søren, Zeigerer, Anja, García‐Cáceres, Cristina, Scheideler, Marcel, Herzig, Stephan, Bartelt, Alexander

“…Abstract Adipocytes are critical regulators of metabolism and energy balance. While white adipocyte dysfunction is a hallmark of obesity‐associated disorders,…”
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Glucagon‐like peptide‐1: The missing link in the metabolic clock? by Brubaker, Patricia L, Gil‐Lozano, Manuel

“…Circadian expression of clock genes in peripheral tissues is critical to the coordinated regulation of intestinal digestive and absorptive functions, insulin…”
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Lipid sensing nuclear receptors involved in the pathogenesis of fatty liver disease by Schweiger, Marion, Arredondo-Lasso, Maria Nieves, Friano, Marika E, Gil-Lozano, Manuel, Herzig, Stephan, Uhlenhaut, Nina Henriette

“…Non-alcoholic fatty liver disease (NAFLD) begins with lipid accumulation and progresses toward inflammation and fibrosis. Nuclear receptors (NRs), like the…”
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Circadian secretion of the intestinal hormone GLP-1 by the rodent L cell by Gil-Lozano, Manuel, Mingomataj, Erli L, Wu, W Kelly, Ridout, Sean A, Brubaker, Patricia L

“…Peripheral clocks are known to modulate circadian patterns of insulin secretion. GLP-1 is an incretin hormone produced by the intestinal L cell that acts as a…”
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High-Fat Diet and Palmitate Alter the Rhythmic Secretion of Glucagon-Like Peptide-1 by the Rodent L-cell by Gil-Lozano, Manuel, Wu, W. Kelly, Martchenko, Alexandre, Brubaker, Patricia L

“…Secretion of the incretin hormone, glucagon-like peptide-1 (GLP-1), by the intestinal L-cell is rhythmically regulated by an independent molecular clock…”
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A miR‐29a‐driven negative feedback loop regulates peripheral glucocorticoid receptor signaling by Glantschnig, Christina, Koenen, Mascha, Gil‐Lozano, Manuel, Karbiener, Michael, Pickrahn, Ines, Williams‐Dautovich, Jasmine, Patel, Rucha, Cummins, Carolyn L., Giroud, Maude, Hartleben, Götz, Vogl, Elena, Blüher, Matthias, Tuckermann, Jan, Uhlenhaut, Henriette, Herzig, Stephan, Scheideler, Marcel

“…ABSTRACTThe glucocorticoid receptor (GR) represents the crucial molecular mediator of key endocrine, glucocorticoid hormone–dependent regulatory circuits,…”
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Editorial: Novel and emerging therapies for the treatment of obesity and related disorders by Amado, Isabel R, Romaní-Pérez, Marina, Fuciños, Pablo, Gil-Lozano, Manuel

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The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1 by Biancolin, Andrew D., Martchenko, Alexandre, Mitova, Emilia, Gurges, Patrick, Michalchyshyn, Everan, Chalmers, Jennifer A., Doria, Alessandro, Mychaleckyj, Josyf C., Adriaenssens, Alice E., Reimann, Frank, Gribble, Fiona M., Gil-Lozano, Manuel, Cox, Brian J., Brubaker, Patricia L.

“…The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted from intestinal L-cells upon nutrient intake. While recent evidence has shown that GLP-1 is…”
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Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2‐Dependent Mitotic Cell Death by Rios Garcia, Marcos, Meissburger, Bettina, Chan, Jessica, Guia, Roldan M., Mattijssen, Frits, Roessler, Stephanie, Birkenfeld, Andreas L., Raschzok, Nathanael, Riols, Fabien, Tokarz, Janina, Giroud, Maude, Gil Lozano, Manuel, Hartleben, Goetz, Nawroth, Peter, Haid, Mark, López, Miguel, Herzig, Stephan, Berriel Diaz, Mauricio

“…Aberrant energy metabolism and cell cycle regulation both critically contribute to malignant cell growth and both processes represent targets for anticancer…”
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Pulmonary GLP-1 Receptor Increases at Birth and Exogenous GLP-1 Receptor Agonists Augmented Surfactant-Protein Levels in Litters From Normal and Nitrofen-Treated Pregnant Rats by Romaní-Pérez, Marina, Outeiriño-Iglesias, Verónica, Gil-Lozano, Manuel, González-Matías, Lucas C, Mallo, Federico, Vigo, Eva

“…The glucagon-like peptide-1 receptor (GLP-1R) is found in a variety of tissues outside of the pancreas. For example, GLP-1R is expressed in the lung, where it…”
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GLP-1(7-36)-amide and Exendin-4 Stimulate the HPA Axis in Rodents and Humans by Gil-Lozano, Manuel, Pérez-Tilve, Diego, Alvarez-Crespo, Mayte, Martís, Aurelio, Fernandez, Ana M, Catalina, Pablo A. F, Gonzalez-Matias, Lucas C, Mallo, Federico

“…Glucagon-like peptide-1 (GLP-1) is a potent insulinotropic peptide expressed in the gut and brain, which is secreted in response to food intake. The levels of…”
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Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous system by Pérez-Tilve, Diego, González-Matías, Lucas, Aulinger, Benedikt A, Alvarez-Crespo, Mayte, Gil-Lozano, Manuel, Alvarez, Elias, Andrade-Olivie, Amalia M, Tschöp, Matthias H, D'Alessio, David A, Mallo, Federico

“…Exendin-4 (Ex-4), an agonist of the glucagon-like peptide-1 receptor (GLP-1R), shares many of the actions of GLP-1 on pancreatic islets, the central nervous…”
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Short-term sleep deprivation with nocturnal light exposure alters time-dependent glucagon-like peptide-1 and insulin secretion in male volunteers by Gil-Lozano, Manuel, Hunter, Paola M, Behan, Lucy-Ann, Gladanac, Bojana, Casper, Robert F, Brubaker, Patricia L

“…The intestinal L cell is the principal source of glucagon-like peptide-1 (GLP-1), a major determinant of insulin release. Because GLP-1 secretion is regulated…”
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Adipocyte Deletion of ADAM17 Leads to Insulin Resistance in Association with Age and HFD in Mice by Lopez Salazar, Valeria, Karikari, Rhoda Anane, Li, Lun, El‐Merahbi, Rabih, Troullinaki, Maria, Wu, Moya, Wiedemann, Tobias, Walth, Alina, Gil Lozano, Manuel, Rohm, Maria, Herzig, Stephan, Georgiadi, Anastasia

“…Background Adam17 has been previously shown to regulate energy expenditure and mitochondria biogenesis in human stem cell derived adipocytes (hMADS)…”
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WITHDRAWN: Adipocyte Deletion of ADAM17 Leads to Insulin Resistance in Association with Age and HFD in Mice by Lopez Salazar, Valeria, Karikari, Rhoda Anane, Li, Lun, El-Merahbi, Rabih, Troullinaki, Maria, Wu, Moya, Wiedemann, Tobias, Walth, Alina, Gil Lozano, Manuel, Rohm, Maria, Herzig, Stephan, Georgiadi, Anastasia

“…Withdrawal: Valeria Lopez Salazar, Rhoda Anane Karikari, Lun Li, Rabih El-Merahbi, Maria Troullinaki, Moya Wu, Tobias Wiedemann, Alina Walth, Manuel Gil…”
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HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling by Giroud, Maude, Tsokanos, Foivos-Filippos, Caratti, Giorgio, Kotschi, Stefan, Khani, Sajjad, Jouffe, Céline, Vogl, Elena S., Irmler, Martin, Glantschnig, Christina, Gil-Lozano, Manuel, Hass, Daniela, Khan, Asrar Ali, Garcia, Marcos Rios, Mattijssen, Frits, Maida, Adriano, Tews, Daniel, Fischer-Posovszky, Pamela, Feuchtinger, Annette, Virtanen, Kirsi A., Beckers, Johannes, Wabitsch, Martin, Uhlenhaut, Henriette, Blüher, Matthias, Tuckermann, Jan, Scheideler, Marcel, Bartelt, Alexander, Herzig, Stephan

“…Aims/hypothesis Adipocytes are critical cornerstones of energy metabolism. While obesity-induced adipocyte dysfunction is associated with insulin resistance…”
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Stressing diabetes? The hidden links between insulinotropic peptides and the HPA axis by Diz-Chaves, Yolanda, Gil-Lozano, Manuel, Toba, Laura, Fandiño, Juan, Ogando, Hugo, González-Matías, Lucas C, Mallo, Federico

“…Diabetes mellitus exerts metabolic stress on cells and it provokes a chronic increase in the long-term activity of the hypothalamus–pituitary–adrenocortical…”
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Corticotropin-Releasing Hormone and the Sympathoadrenal System Are Major Mediators in the Effects of Peripherally Administered Exendin-4 on the Hypothalamic-Pituitary-Adrenal Axis of Male Rats by Gil-Lozano, Manuel, Romaní-Pérez, Marina, Outeiriño-Iglesias, Verónica, Vigo, Eva, González-Matías, Lucas C, Brubaker, Patricia L, Mallo, Federico

“…Glucagon-like peptide-1 (GLP-1) and the GLP-1 receptor agonist, exendin-4 (Ex-4), potently stimulate hypothalamic-pituitary-adrenal (HPA) axis activity after…”
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Effects of prolonged exendin-4 administration on hypothalamic-pituitary-adrenal axis activity and water balance by Gil-Lozano, Manuel, Romaní-Pérez, Marina, Outeiriño-Iglesias, Verónica, Vigo, Eva, Brubaker, Patricia L, González-Matías, Lucas C, Mallo, Federico

“…Exendin-4 (Ex-4) is a natural agonist of the glucagon-like peptide-1 (GLP-1) receptor, currently being used as a treatment for type 2 diabetes mellitus due to…”
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Glucagon-Like Peptide-1 (7-36)-Amide and Exendin-4 Strongly Stimulate the Hypothalamic-Pituitary-Adrenal Axis in Rodents and in Healthy or Diabetic Humans by Gil-Lozano, Manuel, Pérez-Tilve, Diego, Alvarez-Crespo, Mayte, Martís, Aurelio, Fernandez, Ana M., Catalina, Pablo A. F., Gonzalez-Matias, Lucas C., Mallo, Federico

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