Search Results - "Gil Costa, M."

Orbitofrontal cortex is required for optimal waiting based on decision confidence by Lak, Armin, Costa, Gil M, Romberg, Erin, Koulakov, Alexei A, Mainen, Zachary F, Kepecs, Adam

“…Confidence judgments are a central example of metacognition-knowledge about one's own cognitive processes. According to this metacognitive view, confidence…”
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Neural antecedents of self-initiated actions in secondary motor cortex by Murakami, Masayoshi, Vicente, M Inês, Costa, Gil M, Mainen, Zachary F

“…Using in vivo recording of neuronal activities in rat secondary motor cortex and devising a novel task of waiting before performing an action, Murakami et al …”
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Cancer cachexia and its pathophysiology: links with sarcopenia, anorexia and asthenia by Peixoto da Silva, Sara, Santos, Joana M.O., Costa e Silva, Maria Paula, Gil da Costa, Rui M., Medeiros, Rui

“…Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal muscle mass, along with adipose tissue wasting, systemic…”
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Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion by Kaipainen, Arja, Zhang, Ailin, Gil da Costa, Rui M., Lucas, Jared, Marck, Brett, Matsumoto, Alvin M., Morrissey, Colm, True, Lawrence D., Mostaghel, Elahe A., Nelson, Peter S.

“…Background Testosterone is a driver of prostate cancer (PC) growth via ligand‐mediated activation of the androgen receptor (AR). Tumors that have escaped…”
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Malignancy Associated with Low-Risk HPV6 and HPV11: A Systematic Review and Implications for Cancer Prevention by Silva, Leandro Lima da, Teles, Amanda Mara, Santos, Joana M. O, Souza de Andrade, Marcelo, Medeiros, Rui, Faustino-Rocha, Ana I, Oliveira, Paula A, dos Santos, Ana Paula Azevedo, Ferreira Lopes, Fernanda, Braz, Geraldo, Brito, Haissa O, Costa, Rui M. Gil da

“…High-risk human papillomavirus (HPV) is etiologically related to cervical cancer, other anogenital cancers and oropharyngeal carcinomas. Low-risk HPV,…”
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Towards Drug Repurposing in Cancer Cachexia: Potential Targets and Candidates by Santos, Joana M. O., Costa, Alexandra C., Dias, Tânia R., Satari, Setareh, Costa e Silva, Maria Paula, da Costa, Rui M. Gil, Medeiros, Rui

“…As a multifactorial and multiorgan syndrome, cancer cachexia is associated with decreased tolerance to antitumor treatments and increased morbidity and…”
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Dietary Supplementation with the Red Seaweed Porphyra umbilicalis Protects against DNA Damage and Pre-Malignant Dysplastic Skin Lesions in HPV-Transgenic Mice by Santos, Susana, Ferreira, Tiago, Almeida, José, Pires, Maria J, Colaço, Aura, Lemos, Sílvia, Gil da Costa, Rui M, Medeiros, Rui, Bastos, Margarida M S M, Neuparth, Maria J, Abreu, Helena, Pereira, Rui, Pacheco, Mário, Gaivão, Isabel, Rosa, Eduardo, Oliveira, Paula A

“…Some diet profiles are associated with the risk of developing cancer; however, some nutrients show protective effects. is widely consumed, having a balanced…”
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The Effect of Lemon Juice ( Citrus limon L.) Treated with Melatonin on the Health Status and Treatment of K14HPV16 Mice by Badiche-El Hilali, Fátima, Medeiros-Fonseca, Beatriz, Silva, Jéssica, Silvestre-Ferreira, Ana C, Pires, Maria João, Gil da Costa, Rui M, Peixoto, Francisco, Oliveira, Paula A, Valero, Daniel

“…Lemon is a fruit rich in antioxidant properties and has several health benefits, namely the reduction of skin edema and anticarcinogenic properties, which are…”
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Pulegone and Eugenol Oral Supplementation in Laboratory Animals: Results from Acute and Chronic Studies by Ribeiro-Silva, Carla M, Faustino-Rocha, Ana I, Gil da Costa, Rui M, Medeiros, Rui, Pires, Maria J, Gaivão, Isabel, Gama, Adelina, Neuparth, Maria J, Barbosa, Joana V, Peixoto, Francisco, Magalhães, Fernão D, Bastos, Margarida M. S. M, Oliveira, Paula A

“…Essential oils are natural compounds used by humans for scientific purposes due to their wide range of properties. Eugenol is mostly present in clove oil,…”
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Abnormal Protein Glycosylation and Activated PI3K/Akt/mTOR Pathway: Role in Bladder Cancer Prognosis and Targeted Therapeutics by Costa, Céu, Pereira, Sofia, Lima, Luís, Peixoto, Andreia, Fernandes, Elisabete, Neves, Diogo, Neves, Manuel, Gaiteiro, Cristiana, Tavares, Ana, Gil da Costa, Rui M, Cruz, Ricardo, Amaro, Teresina, Oliveira, Paula A, Ferreira, José Alexandre, Santos, Lúcio L

“…Muscle invasive bladder cancer (MIBC, stage ≥T2) is generally associated with poor prognosis, constituting the second most common cause of death among…”
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The Red Seaweed Grateloupia turuturu Prevents Epidermal Dysplasia in HPV16-Transgenic Mice by Almeida, José, Ferreira, Tiago, Santos, Susana, Pires, Maria J, da Costa, Rui M Gil, Medeiros, Rui, Bastos, Margarida M S M, Neuparth, Maria J, Faustino-Rocha, Ana I, Abreu, Helena, Pereira, Rui, Pacheco, Mário, Gaivão, Isabel, Rosa, Eduardo, Oliveira, Paula A

“…The role of dietary profiles in promoting or reducing the risk of multiple types of cancer is increasingly clear, driving the search for balanced foods and…”
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A comparison of prostate cancer cell transcriptomes in 2D monoculture vs 3D xenografts identify consistent gene expression alterations associated with tumor microenvironments by Brady, Lauren, Gil da Costa, Rui M., Coleman, Ilsa M., Matson, Clinton K., Risk, Michael C., Coleman, Roger T., Nelson, Peter S.

“…Background Prostate cancer (PC) research has relied heavily on patient‐derived cell lines, which may be used for in vitro (two‐dimensional [2D]) studies or…”
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PIK3CA Gene Mutations in HNSCC: Systematic Review and Correlations with HPV Status and Patient Survival by Cochicho, Daniela, Esteves, Susana, Rito, Miguel, Silva, Fernanda, Martins, Luís, Montalvão, Pedro, Cunha, Mário, Magalhães, Miguel, Gil da Costa, Rui M, Felix, Ana

“…PIK3CA mutations are believed to contribute to the pathogenesis of human papillomavirus (HPV)-associated head and neck squamous cell carcinomas (HNSCC). This…”
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Curcumin and Rutin Down-regulate Cyclooxygenase-2 and Reduce Tumor-associated Inflammation in HPV16-Transgenic Mice by Moutinho, Magda S S, Aragão, Sofia, Carmo, Diogo, Casaca, Fátima, Silva, Sandra, Ribeiro, Joana, Sousa, Hugo, Pires, Isabel, Queiroga, Felisbina, Colaço, Bruno, Medeiros, Rui, Oliveira, Paula A, Lopes, Carlos, Bastos, Margarida M S M, DA Costa, Rui M Gil

“…Cyclo-oxygenase-2 (COX2) plays a prominent role in carcinogenesis. This study addresses the effects of two nutraceutical compounds on the expression of COX2…”
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Characterization of the Human Papillomavirus 16 Oncogenes in K14HPV16 Mice: Sublineage A1 Drives Multi-Organ Carcinogenesis by Cochicho, Daniela, Nunes, Alexandra, Gomes, João Paulo, Martins, Luís, Cunha, Mário, Medeiros-Fonseca, Beatriz, Oliveira, Paula, Bastos, Margarida M. S. M., Medeiros, Rui, Mendonça, Joana, Vieira, Luis, Gil da Costa, Rui M., Felix, Ana

“…The study of human papillomavirus (HPV)-induced carcinogenesis uses multiple in vivo mouse models, one of which relies on the cytokeratin 14 gene promoter to…”
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Inhalation of Bacterial Cellulose Nanofibrils Triggers an Inflammatory Response and Changes Lung Tissue Morphology of Mice by Silva-Carvalho, Ricardo, Silva, João P, Ferreirinha, Pedro, Leitão, Alexandre F, Andrade, Fábia K, Gil da Costa, Rui M, Cristelo, Cecília, Rosa, Morsyleide F, Vilanova, Manuel, Gama, F Miguel

“…In view of the growing industrial use of Bacterial cellulose (BC), and taking into account that it might become airborne and be inhaled after industrial…”
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A role for microRNA-155 expression in microenvironment associated to HPV-induced carcinogenesis in K14-HPV16 transgenic mice by Paiva, Isabel, Gil da Costa, Rui M, Ribeiro, Joana, Sousa, Hugo, Bastos, Margarida, Faustino-Rocha, Ana, Rocha, Ana Faustino Carlos, Lopes, Carlos, Oliveira, Paula A, Medeiros, Rui

“…Human Papillomavirus cause a number of diseases most notably cervical cancer. K14-HPV16 transgenic mice expressing the HPV16 early genes in squamous epithelial…”
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N-diethylnitrosamine mouse hepatotoxicity: Time-related effects on histology and oxidative stress by Paula Santos, Nuno, Colaço, Aura, Gil da Costa, Rui M., Manuel Oliveira, Maria, Peixoto, Francisco, Alexandra Oliveira, Paula

“…Animal models, namely mice, have been used to study chemically induced carcinogenesis due to their similarity to the histological and genetic features of human…”
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Characterizing the Inflammatory Microenvironment in K14-HPV16 Transgenic Mice: Mast Cell Infiltration and MicroRNA Expression by Costa, Alexandra C, Santos, Joana M O, Medeiros-Fonseca, Beatriz, Oliveira, Paula A, Bastos, Margarida M S M, Brito, Haissa O, Gil da Costa, Rui M, Medeiros, Rui

“…High-risk human papillomavirus (HPV) is the etiologic agent of several types of cancer. Mast cells’ role as either a driving or opposing force for cancer…”
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Limited Role of Secreted Aspartyl Proteinases Sap1 to Sap6 in Candida albicans Virulence and Host Immune Response in Murine Hematogenously Disseminated Candidiasis by Correia, Alexandra, Lermann, Ulrich, Teixeira, Luzia, Cerca, Filipe, Botelho, Sofia, Gil da Costa, Rui M, Sampaio, Paula, Gärtner, Fátima, Morschhäuser, Joachim, Vilanova, Manuel, Pais, Célia

“…Candida albicans secreted aspartyl proteinases (Saps) are considered virulence-associated factors. Several members of the Sap family were claimed to play a…”
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