Search Results - "Gil, Chan Hee"
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Nasal symbiont Staphylococcus epidermidis restricts the cellular entry of influenza virus into the nasal epithelium
Published in NPJ biofilms and microbiomes (13-04-2022)“…Our recent study presented that human nasal commensal Staphylococcus epidermidis could potentiate antiviral immunity in the nasal mucosa through…”
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Symbiotic microbiome Staphylococcus epidermidis restricts IL-33 production in allergic nasal epithelium via limiting the cellular necroptosis
Published in BMC microbiology (26-05-2023)“…Allergic rhinitis (AR) is characterized by airway inflammation in nasal mucosa from inhaled allergens and interleukin (IL)-33 is the potent inducer of Th2…”
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Symbiotic microbiome Staphylococcus aureus from human nasal mucus modulates IL-33-mediated type 2 immune responses in allergic nasal mucosa
Published in BMC microbiology (07-10-2020)“…The host-microbial commensalism can shape the innate immune responses in respiratory mucosa and nasal microbiome also modulates front-line immune mechanism in…”
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Intranasal inoculation of IFN-λ resolves SARS-CoV-2 lung infection via the rapid reduction of viral burden and improvement of tissue damage
Published in Frontiers in immunology (29-11-2022)“…The innate immune responses of upper airway could further our understanding toward antiviral strategies against SARS-CoV-2. We characterize the potential of…”
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Chronic rhinosinusitis endotypes associate with distinct local cytokine milieus that shape the distribution of innate lymphoid cells
Published in Allergy (Copenhagen) (01-07-2022)Get full text
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Anti-photoaging properties of the phosphodiesterase 3 inhibitor cilostazol in ultraviolet B-irradiated hairless mice
Published in Scientific reports (03-08-2016)“…We investigated whether cilostazol, an activator of cyclic adenosine monophosphate (cAMP)-dependent intracellular signaling, could inhibit ultraviolet B (UVB)…”
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The nasal symbiont Staphylococcus species restricts the transcription of SARS-CoV-2 entry factors in human nasal epithelium
Published in iScience (22-10-2021)“…Emerging evidence indicates that severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is transmitted through the human nasal mucosa via the…”
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Inhaled delivery of Interferon-lambda restricts epithelial-derived Th2 inflammation in allergic asthma
Published in Cytokine (Philadelphia, Pa.) (01-07-2019)“…•Allergic asthma is characterized by dysregulation of Th2 cytokines.•Th2 cytokines are involved in impaired interferon induction in asthmatic mice.•Intranasal…”
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The influence of interferon-lambda on restricting Middle East Respiratory Syndrome Coronavirus replication in the respiratory epithelium
Published in Antiviral research (01-08-2020)“…Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes severe respiratory in human with high mortality and it has been a challenge to determine optimum…”
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Inhaled delivery of recombinant interferon-lambda restores allergic inflammation after development of asthma by controlling Th2- and Th17-cell-mediated immune responses
Published in International immunopharmacology (01-11-2022)“…[Display omitted] •Allergic asthma is characterized by dysregulation of Th2 cells-derived cytokines in the respiratory tract but Th17-mediated inflammation…”
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Inhalation Delivery of Interferon-λ-Loaded Pulmonary Surfactant Nanoparticles Induces Rapid Antiviral Immune Responses in the Lung
Published in ACS applied materials & interfaces (06-03-2024)“…The interferon-λ (IFN-λ)-regulated innate immune responses in the airway expand our understanding toward antiviral strategies against influenza A virus (IAV)…”
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