Search Results - "Gijs, Martin A. M"
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Micro-optics for microfluidic analytical applications
Published in Chemical Society reviews (19-02-2018)“…This critical review summarizes the developments in the integration of micro-optical elements with microfluidic platforms for facilitating detection and…”
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Super-Resolution Imaging of a Dielectric Microsphere Is Governed by the Waist of Its Photonic Nanojet
Published in Nano letters (10-08-2016)“…Dielectric microspheres with appropriate refractive index can image objects with super-resolution, that is, with a precision well beyond the classical…”
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Microfluidic Applications of Magnetic Particles for Biological Analysis and Catalysis
Published in Chemical reviews (10-03-2010)“…The use of magnetic particles in microfluidic devices is studied. Such particles can aid in the mixing and catalysis of biochemical compounds…”
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Photonic Nanojet Array for Fast Detection of Single Nanoparticles in a Flow
Published in Nano letters (11-03-2015)“…We detect by optical microscopy Au and fluorescent nanoparticles (NPs) during their motion in water-based medium, using an array of dielectric microspheres…”
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Super-Resolution Biological Microscopy Using Virtual Imaging by a Microsphere Nanoscope
Published in Small (Weinheim an der Bergstrasse, Germany) (01-05-2014)“…Super‐resolution imaging of sub‐cellular organelles and nanostructures is achieved by simply putting high‐refractive index glass microspheres on a sample in…”
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High Throughput-Per-Footprint Inertial Focusing
Published in Small (Weinheim an der Bergstrasse, Germany) (26-08-2013)“…Matching the scale of microfluidic flow systems with that of microelectronic chips for realizing monolithically integrated systems still needs to be…”
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Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle
Published in eLife (19-04-2023)“…Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and…”
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Microfluidic processor allows rapid HER2 immunohistochemistry of breast carcinomas and significantly reduces ambiguous (2+) read-outs
Published in Proceedings of the National Academy of Sciences - PNAS (02-04-2013)“…Biomarker analysis is playing an essential role in cancer diagnosis, prognosis, and prediction. Quantitative assessment of immunohistochemical biomarker…”
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Droplet-Based DNA Purification in a Magnetic Lab-on-a-Chip
Published in Angewandte Chemie International Edition (05-05-2006)“…Merge, mix, split, and transport are the main manipulation steps used for on‐chip droplet‐based DNA purification (see figure). The system is able to extract…”
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Microtextured Substrates and Microparticles Used as in Situ Lenses for On-Chip Immunofluorescence Amplification
Published in Analytical chemistry (Washington) (19-02-2013)“…We propose a concept for enhancing the fluorescent detection signal of on-chip immunoassays by using three-dimensional 3 and 8 μm size microtextured structures…”
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Effect of inoculum size and antibiotics on bacterial traveling bands in a thin microchannel defined by optical adhesive
Published in Microsystems & nanoengineering (22-10-2021)“…Phenotypic diversity in bacterial flagella-induced motility leads to complex collective swimming patterns, appearing as traveling bands with transient locally…”
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Microfluidic systems for infectious disease diagnostics
Published in Lab on a chip (27-02-2024)“…Microorganisms, encompassing both uni- and multicellular entities, exhibit remarkable diversity as omnipresent life forms in nature. They play a pivotal role…”
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Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
Published in Lab on a chip (07-11-2017)“…In a typical high-throughput drug screening (HTS) process, up to millions of chemical compounds are applied to cells cultured in well plates, aiming to find…”
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Force microscopy of the Caenorhabditis elegans embryonic eggshell
Published in Microsystems & nanoengineering (04-05-2020)“…Assays focusing on emerging biological phenomena in an animal’s life can be performed during embryogenesis. While the embryo of Caenorhabditis elegans has been…”
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Ultrasensitive protein detection: a case for microfluidic magnetic bead-based assays
Published in Lab on a chip (21-12-2013)“…We review the use of magnetic micro- and nanoparticles ('magnetic beads') in microfluidic systems for ultrasensitive protein detection. During recent years…”
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Spontaneous Formation of CdSe Photoluminescent Nanotubes with Visible-Light Photocatalytic Performance
Published in ACS central science (26-06-2019)“…Two-dimensional (2D) colloidal CdSe nanocrystals (NCs) with precise atomic-scale thickness have attracted intensive attention in recent years due to their…”
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Polydimethylsiloxane microstructure-induced acoustic streaming for enhanced ultrasonic DNA fragmentation on a microfluidic chip
Published in Lab on a chip (25-10-2022)“…Next-generation sequencing (NGS) is an essential technology for DNA identification in genomic research. DNA fragmentation is a critical step for NGS and doing…”
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Exploring Living Multicellular Organisms, Organs, and Tissues Using Microfluidic Systems
Published in Chemical reviews (08-05-2013)“…Sivagnanam and Gijs examine living multicellular organisms, organs, and tissues using microfluidic systems…”
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Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays
Published in Lab on a chip (14-03-2023)“…Biochemical reaction rates in microfluidic systems are known to be limited by the diffusional transport of reagents, leading often to lowered sensitivity…”
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Magnetic bead handling on-chip: new opportunities for analytical applications
Published in Microfluidics and nanofluidics (01-11-2004)“…This review describes recent advances in the handling and manipulation of magnetic particles in microfluidic systems. Starting from the properties of magnetic…”
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