Search Results - "Giglio, Jose R."
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Isolation, enzymatic characterization and antiedematogenic activity of the first reported rattlesnake hyaluronidase from Crotalus durissus terrificus venom
Published in Biochimie (01-12-2012)“…A hyaluronidase (CdtHya1) from Crotalus durissus terrificus snake venom (CdtV) was isolated and showed to exhibit a high activity on hyaluronan cleavage…”
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2
Medicinal plants with inhibitory properties against snake venoms
Published in Current medicinal chemistry (01-01-2005)“…Envenomations due to snake bites are commonly treated by parenteral administration of horse or sheep-derived polyclonal antivenoms aimed at the neutralization…”
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3
Structural and functional characterization of a γ-type phospholipase A2 inhibitor from bothrops jararacussu snake plasma
Published in Current topics in medicinal chemistry (01-10-2011)“…Phospholipases A2 (PLA2s) from snake venoms comprise a group of 14-18 kDa proteins, responsible for several toxic effects induced by the whole venom…”
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Tityus serrulatus scorpion venom and toxins: an overview
Published in Protein and peptide letters (01-08-2009)“…Tityus serrulatus is considered the most dangerous scorpion in South America and responsible for most of the fatal cases. This review will focus on Tityus…”
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Antitumoural Effect of an l‐Amino Acid Oxidase Isolated from Bothrops jararaca Snake Venom
Published in Basic & clinical pharmacology & toxicology (01-06-2008)“…: An l‐amino acid oxidase (BjarLAAO‐I) from Bothrops jararaca snake venom was highly purified using a stepwise sequential chromatography on Sephadex G‐75,…”
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Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity
Published in Peptides (New York, N.Y. : 1980) (01-12-2007)“…BjussuMP-II is an acidic low molecular weight metalloprotease ( Mr ∼ 24,000 and pI ∼ 6.5), isolated from Bothrops jararacussu snake venom. The chromatographic…”
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Quantification of Nicotine in Commercial Brand Cigarettes: How Much Is Inhaled by the Smoker?
Published in Biochemistry and molecular biology education (01-09-2010)“…The main objective of this experiment is to determine the amount of nicotine in commercial brand cigarettes by means of a nonaqueous acid-base titration. A…”
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Cloning and identification of a complete cDNA coding for a bactericidal and antitumoral acidic phospholipase A2 from Bothrops jararacussu venom
Published in The Protein Journal (01-05-2004)“…In order to better understand the function of acidic phospholipases A2 (PLA2s) from snake venoms, expressed sequence tags (ESTs) that code for acidic PLA2s…”
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Biochemical, functional, structural and phylogenetic studies on Intercro, a new isoform phospholipase A2 from Crotalus durissus terrificus snake venom
Published in Biochimie (01-12-2013)“…Crotoxin is a neurotoxin from Crotalus durissus terrificus venom that shows immunomodulatory, anti-inflammatory, antimicrobial, antitumor and analgesic…”
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10
Platelet aggregation and antibacterial effects of an l-amino acid oxidase purified from Bothrops alternatus snake venom
Published in Bioorganic & medicinal chemistry (01-06-2004)“…N-terminal sequence is: A D V R N P L E E F R E T D Y E V L The present investigation reports the isolation and biochemical characterization of an l-amino acid…”
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Isolation and functional characterization of a new myotoxic acidic phospholipase A(2) from Bothrops pauloensis snake venom
Published in Toxicon (Oxford) (01-07-2007)“…This article reports the purification procedure and the biochemical/functional characterization of Bp-PLA(2), a new myotoxic acidic phospholipase A(2) from…”
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12
BjussuSP-I: A new thrombin-like enzyme isolated from Bothrops jararacussu snake venom
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-11-2008)“…A thrombin-like enzyme named BjussuSP-I, isolated from B. jararacussu snake venom, is an acidic single chain glycoprotein with approximately 6% sugar,…”
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Expression of Human Recombinant Antibody Fragments Capable of Partially Inhibiting the Phospholypase Activity of Crotalus durissus terrificus Venom
Published in Basic & clinical pharmacology & toxicology (01-08-2009)“…: Crotoxin is the main toxic component of the South American rattlesnake Crotalus durissus terrificus venom. It is composed of two different subunits: CA,…”
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14
Evaluation of three Brazilian antivenom ability to antagonize myonecrosis and hemorrhage induced by Bothrops snake venoms in a mouse model
Published in Toxicon (Oxford) (01-08-2007)“…Despite preventing death after snakebites, there is little evidence that polyvalent antivenoms (PAVs) protect against myotoxicity and local damages. We…”
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15
Antihemorrhagic, antinucleolytic and other antiophidian properties of the aqueous extract from Pentaclethra macroloba
Published in Journal of ethnopharmacology (22-08-2005)“…Several Brazilian plants have been utilized in folk medicine as active agents against various effects induced by snake venoms. The inhabitants of the Amazon…”
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A hyaluronidase from Tityus serrulatus scorpion venom: isolation, characterization and inhibition by flavonoids
Published in Toxicon (Oxford) (01-10-2001)“…The purification procedure of a hyaluronidase from Tityus serrulatus scorpion venom is described. It involves basically an ion-exchange chromatography on…”
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17
Human neutrophil migration in vitro induced by secretory phospholipases A2: a role for cell surface glycosaminoglycans
Published in Biochemical pharmacology (2002)“…The purpose of this study was to examine the ability of type I- (porcine pancreas and Naja mocambique mocambique venom), type II- (bothropstoxin-I,…”
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Pathological alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi snake venom
Published in Biochimie (01-06-2001)“…The pathological alterations induced by neuwiedase, a 22 kDa class P-I metalloproteinase from the venom of the South American pit viper Bothrops neuwiedi, were…”
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Chemical modifications of phospholipases A2 from snake venoms: effects on catalytic and pharmacological properties
Published in Toxicon (Oxford) (15-12-2003)“…Phospholipases A2 (PLA2s) constitute major components of snake venoms and have been extensively investigated not only because they are very abundant in these…”
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20
Mast cell degranulation induced by two phospholipase A2 homologues : Dissociation between enzymatic and biological activities
Published in European journal of pharmacology (19-02-1998)“…Bothropstoxin-I and bothropstoxin-II are phospholipase A2 homologues isolated from Bothrops jararacussu snake venom. The former is devoid of phospholipase A2…”
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