Search Results - "Gigg, John"

Increased hippocampal excitability in the 3xTgAD mouse model for Alzheimer's disease in vivo by Davis, Katherine E, Fox, Sarah, Gigg, John

“…Mouse Alzheimer's disease (AD) models develop age- and region-specific pathology throughout the hippocampal formation. One recently established pathological…”
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SOCIAL PREFERENCE IN THE THREE-CHAMBER SOCIAL INTERACTION TASK IS DEPENDENT ON NOVELTY RATHER THAN STIMULUS TYPE IN FEMALE C57/BL MICE by Landreth, Katie, Radu, Patricia, Harte, Michael, Gigg, John

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Melanopsin contributions to irradiance coding in the thalamo-cortical visual system by Brown, Timothy M, Gias, Carlos, Hatori, Megumi, Keding, Sheena R, Semo, Ma'ayan, Coffey, Peter J, Gigg, John, Piggins, Hugh D, Panda, Satchidananda, Lucas, Robert J

“…Photoreception in the mammalian retina is not restricted to rods and cones but extends to a subset of retinal ganglion cells expressing the photopigment…”
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Episodic-like memory for what-where-which occasion is selectively impaired in the 3xTgAD mouse model of Alzheimer's disease by Davis, Katherine E, Easton, Alexander, Eacott, Madeline J, Gigg, John

“…Episodic memory loss is a defining feature of early-stage Alzheimer's disease (AD). A test of episodic-like memory for the rat, the What-Where-Which occasion…”
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Maternal immune activation affects female offspring whisker movements during object exploration in a rat model of neurodevelopmental disorders by Simanaviciute, Ugne, Potter, Harry G., Hager, Reinmar, Glazier, Jocelyn, Hodson-Tole, Emma, Gigg, John, Grant, Robyn

“…Poly I:C rat offspring are used to investigate the effects of in utero exposure to maternal immune activation (MIA) and have been suggested as a model of…”
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Timed daily exercise remodels circadian rhythms in mice by Hughes, Alun Thomas Lloyd, Samuels, Rayna Eve, Baño-Otálora, Beatriz, Belle, Mino David Charles, Wegner, Sven, Guilding, Clare, Northeast, Rebecca Catrin, Loudon, Andrew Stewart Irvine, Gigg, John, Piggins, Hugh David

“…Regular exercise is important for physical and mental health. An underexplored and intriguing property of exercise is its actions on the body’s 24 h or…”
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Effects of increased spatial complexity on behavioural development and task performance in Lister Hooded rats by Lyst, Sophie J, Davis, Katherine, Gigg, John, Hager, Reinmar

“…Enhancing laboratory animal welfare, particularly in rodents, has been achieved through environmental enrichment in caging systems. Traditional enrichment such…”
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The subiculum: a review of form, physiology and function by O'Mara, S M, Commins, S, Anderson, M, Gigg, J

“…We review the neuroanatomical, neurophysiological and functional properties of the mammalian subiculum in this paper. The subiculum is a pivotal structure…”
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Phase-locking of bursting neuronal firing to dominant LFP frequency components by Constantinou, Maria, Elijah, Daniel H., Squirrell, Daniel, Gigg, John, Montemurro, Marcelo A.

“…Neuronal firing in the hippocampal formation relative to the phase of local field potentials (LFP) has a key role in memory processing and spatial navigation…”
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Inverse Current Source Density Method in Two Dimensions: Inferring Neural Activation from Multielectrode Recordings by Łęski, Szymon, Pettersen, Klas H., Tunstall, Beth, Einevoll, Gaute T., Gigg, John, Wójcik, Daniel K.

“…The recent development of large multielectrode recording arrays has made it affordable for an increasing number of laboratories to record from multiple brain…”
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The subiculum comes of age by de la Prida, Liset Menendez, Totterdell, Susan, Gigg, John, Miles, Richard

“…The subiculum has long been considered as a simple bidirectional relay region interposed between the hippocampus and the temporal cortex. Recent evidence,…”
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Quantifying the visual information sourced from melanopsin photoreceptors in mouse LGN field responses by Siadatnejad, Sohail, Brown, Timothy M, Gigg, John, Piggins, Hugh D, Lucas, Robert J, Montemurro, Marcelo A

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Neural mechanisms underlying psilocybin’s therapeutic potential – the need for preclinical in vivo electrophysiology by Smausz, Rebecca, Neill, Joanna, Gigg, John

“…Psilocybin is a naturally occurring psychedelic compound with profound perception-, emotion- and cognition-altering properties and great potential for treating…”
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Quantifying how much attention rodents allocate to motivationally-salient objects with a novel object preference test by Hornoiu, Iasmina, Gigg, John, Talmi, Deborah

“…The allocation of attention can be modulated by the emotional value of a stimulus. In order to understand the biasing influence of emotion on attention…”
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Functional ultrasound imaging of recent and remote memory recall in the associative fear neural network in mice by Grohs-Metz, Gillian, Smausz, Rebecca, Gigg, John, Boeckers, Tobias, Hengerer, Bastian

“…Emotional learning and memory are affected in numerous psychiatric disorders. At a systems level, however, the underlying neural circuitry is not well defined…”
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Synaptic biomarker reduction and impaired cognition in the sub-chronic PCP mouse model for schizophrenia by Gigg, John, McEwan, Francesca, Smausz, Rebecca, Neill, Joanna, Harte, Michael K

“…Background: Sub-chronic phencyclidine treatment (scPCP) provides a translational rat model for cognitive impairments associated with schizophrenia (CIAS). CIAS…”
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The projection from hippocampal area CA1 to the subiculum sustains long-term potentiation by Commins, Sean, Gigg, John, Anderson, Michael, OʼMara, Shane M

“…LONG-TERM potentiation (LTP) is a popular model of the synaptic plasticity which may be engaged by the biological processes underlying learning and memory…”
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Episodic-like memory is sensitive to both Alzheimer's-like pathological accumulation and normal ageing processes in mice by Davis, Katherine E., Eacott, Madeline J., Easton, Alexander, Gigg, John

“…•3xTgAD mice have intact WWWhich episodic-like memory at an early pathological stage (3 months old).•3xTgAD mice exhibit severe impairment in WWWhich…”
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Early‐stage hippocampal hyperexcitability and impaired synaptic plasticity in the TgF344‐AD rat model of Alzheimer’s disease by Sun, Yuhong, Rimmer, Lauren, Pezze, Marie Astrid, Bast, Tobias, Gigg, John, Harte, Michael

“…Background The transgenic TgF344‐AD (TG) rat is emerging as a useful model for investigating age‐dependent AD features that include behavioural,…”
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Postnatal light alters hypothalamic-pituitary-adrenal axis function and induces a depressive-like phenotype in adult mice by Coleman, Georgia, Gigg, John, Canal, Maria Mercè

“…The postnatal light environment that a mouse experiences during the critical first three postnatal weeks has long‐term effects on both its circadian rhythm…”
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