Search Results - "Giffen, Carol"
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Providing researchers with online access to NHLBI biospecimen collections: The results of the first six years of the NHLBI BioLINCC program
Published in PloS one (14-06-2017)“…The National Heart, Lung, and Blood Institute (NHLBI), within the United States' National Institutes of Health (NIH), established the Biologic Specimen and…”
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Use of the National Heart, Lung, and Blood Institute Data Repository
Published in The New England journal of medicine (11-05-2017)“…BioLINCC is the data repository of the National Heart, Lung, and Blood Institute. This article describes the data from NHLBI trials that are in the repository…”
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A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
Published in Nature genetics (01-09-2010)“…We conducted a genome-wide association study of gastric cancer and esophageal squamous cell carcinoma (ESCC) in ethnic Chinese subjects in which we genotyped…”
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Integrated analysis of genome-wide miRNAs and targeted gene expression in esophageal squamous cell carcinoma (ESCC) and relation to prognosis
Published in BMC cancer (06-05-2020)“…Esophageal squamous cell carcinoma (ESCC) is a leading cause of cancer death worldwide and in China. We know miRNAs influence gene expression in tumorigenesis,…”
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Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Published in Cancer research (Chicago, Ill.) (01-04-2016)“…Gastric cancer and esophageal cancer are the second and sixth leading causes of cancer-related death worldwide. Multiple genomic alterations underlying gastric…”
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Identification of new susceptibility loci for gastric non-cardia adenocarcinoma: pooled results from two Chinese genome-wide association studies
Published in Gut (01-04-2017)“…Although several genome-wide association studies (GWAS) of non-cardia gastric cancer have been published, more novel association signals could be exploited by…”
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Mutational signatures in 175 Chinese gastric cancer patients
Published in BMC cancer (30-09-2024)“…Gastric cancer (GC), a molecularly heterogeneous disease, is the third leading cause of cancer death worldwide. The majority of GC cases worldwide occur in…”
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Cigarette Smoking and Adenocarcinomas of the Esophagus and Esophagogastric Junction: A Pooled Analysis From the International BEACON Consortium
Published in JNCI : Journal of the National Cancer Institute (08-09-2010)“…Background Previous studies that showed an association between smoking and adenocarcinomas of the esophagus and esophagogastric junction were limited in their…”
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Comparison of global gene expression of gastric cardia and noncardia cancers from a high-risk population in china
Published in PloS one (22-05-2013)“…To profile RNA expression in gastric cancer by anatomic subsites as an initial step in identifying molecular subtypes and providing targets for early detection…”
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Family history of cancer and risk for esophageal and gastric cancer in Shanxi, China
Published in BMC cancer (05-08-2009)“…Family history (FH) by different relative types and risk of upper gastrointestinal (UGI) cancers has been only rarely reported; the data on UGI cancer survival…”
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Risk factors for esophageal and gastric cancers in Shanxi Province, China: A case–control study
Published in Cancer epidemiology (01-12-2011)“…Abstract Objective : Smoking and alcohol consumption explain little of the risk for upper-gastrointestinal (UGI) cancer in China, where over half of all cases…”
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Esophageal Squamous Dysplasia is Common in Asymptomatic Kenyans: A Prospective, Community-Based, Cross-Sectional Study
Published in The American journal of gastroenterology (01-04-2016)“…Esophageal squamous cell carcinoma (ESCC) is endemic in east Africa and is a leading cause of cancer death among Kenyans. The asymptomatic precursor lesion of…”
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Association of high-evidence gastric cancer susceptibility loci and somatic gene expression levels with survival
Published in Carcinogenesis (New York) (26-10-2017)“…Eleven high-evidence single-nucleotide polymorphisms (SNPs) at nine loci for gastric cancer (GC) risk were reported, but their associations with survival…”
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Providing Contemporary Access to Historical Biospecimen Collections: Development of the NHLBI Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC)
Published in Biopreservation and biobanking (01-08-2015)“…The National Heart, Lung, and Blood Institute (NHLBI), within the United States' National Institutes of Health (NIH), established a Biorepository in 1976 that…”
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Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population
Published in Carcinogenesis (New York) (01-07-2013)“…The DNA repair pathways help to maintain genomic integrity and therefore genetic variation in the pathways could affect the propensity to develop cancer…”
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Association Between Circulating Levels of Sex Steroid Hormones and Barrett’s Esophagus in Men: A Case–Control Analysis
Published in Clinical gastroenterology and hepatology (01-04-2015)“…Background & Aims Esophageal adenocarcinoma is believed to result from the progression of gastroesophageal reflux disease to erosive esophagitis and…”
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Common genetic variants in epigenetic machinery genes and risk of upper gastrointestinal cancers
Published in International journal of epidemiology (01-08-2015)“…Populations in north central China are at high risk for oesophageal squamous cell carcinoma (ESCC) and gastric cancer (GC), and genetic variation in epigenetic…”
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Randomized, Placebo-Controlled, Esophageal Squamous Cell Cancer Chemoprevention Trial of Selenomethionine and Celecoxib
Published in Gastroenterology (New York, N.Y. 1943) (01-09-2005)“…Background & Aims: Esophageal squamous cell carcinoma remains a leading cause of cancer death worldwide. Squamous dysplasia, the accepted histological…”
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Global changes in gene expression of Barrett's esophagus compared to normal squamous esophagus and gastric cardia tissues
Published in PloS one (01-04-2014)“…Barrett's esophagus (BE) is a metaplastic precursor lesion of esophageal adenocarcinoma (EA), the most rapidly increasing cancer in western societies. While…”
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GWAS follow-up study of esophageal squamous cell carcinoma identifies potential genetic loci associated with family history of upper gastrointestinal cancer
Published in Scientific reports (05-07-2017)“…Based on our initial genome-wide association study (GWAS) on esophageal squamous cell carcinoma (ESCC) in Han Chinese, we conducted a follow-up study to…”
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