Search Results - "Giffard, R.G."

Agmatine reduces infarct area in a mouse model of transient focal cerebral ischemia and protects cultured neurons from ischemia-like injury by Kim, J.H., Yenari, M.A., Giffard, R.G., Cho, S.W., Park, K.A., Lee, J.E.

“…Agmatine is a primary amine formed by the decarboxylation of l-arginine synthesized in mammalian brain. In this study, we investigated the neuroprotective…”
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Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar by Jevtovic-Todorovic, V, Absalom, A.R., Blomgren, K, Brambrink, A, Crosby, G, Culley, D.J., Fiskum, G, Giffard, R.G., Herold, K.F., Loepke, A.W., Ma, D, Orser, B.A., Planel, E, Slikker, W, Soriano, S.G., Stratmann, G, Vutskits, L, Xie, Z, Hemmings, H.C.

“…Although previously considered entirely reversible, general anaesthesia is now being viewed as a potentially significant risk to cognitive performance at both…”
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Increasing vulnerability of astrocytes to oxidative injury with age despite constant antioxidant defenses by Papadopoulos, M.C, Koumenis, I.L, Yuan, T.Y, Giffard, R.G

“…This paper investigates the vulnerability of astrocytes to oxidative injury as a function of age in culture in mice. Primary murine cortical astrocyte cultures…”
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Central Neuroinflammation in Cerebral Ischemia : The Role of Glia by Stary, C.M, Li, L, Giffard, R.G

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Chapter 27 - Central Neuroinflammation in Cerebral Ischemia: The Role of Glia by Stary, C.M., Li, L., Giffard, R.G.

“…One reason for the translational failure of antiinflammatory approaches for stroke therapy is that strategies targeting neuronal survival alone may be…”
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Ultrastructure of excitotoxic neuronal death in murine cortical culture by Regan, R.F., Panter, S.S., Witz, A., Tilly, J.L., Giffard, R.G.

“…Ischemic and traumatic brain injury are likely to involve neuronal injury triggered by glutamate receptor overactivation. Although excitotoxic neuronal injury…”
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Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin by Monyer, H, Giffard, R G, Hartley, D M, Dugan, L L, Goldberg, M P, Choi, D W

“…We examined glutamate-mediated neurotoxicity in cortical cell cultures pretreated with 1-5 micrograms/ml tetanus toxin to attenuate the Ca(2+)-dependent…”
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