Search Results - "Giessel, Andrew"

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  1. 1
    Olfactory maps, circuits and computations

    Olfactory maps, circuits and computations by Giessel, Andrew J, Datta, Sandeep Robert

    Published in Current opinion in neurobiology (01-02-2014)
    “…Highlights • The glomerular organization in the mammalian olfactory bulb is differentially transformed in higher-order olfactory areas. • The microcircuitry of…”
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  2. 2
    M1 Muscarinic Receptors Boost Synaptic Potentials and Calcium Influx in Dendritic Spines by Inhibiting Postsynaptic SK Channels

    M1 Muscarinic Receptors Boost Synaptic Potentials and Calcium Influx in Dendritic Spines by Inhibiting Postsynaptic SK Channels by Giessel, Andrew J., Sabatini, Bernardo L.

    Published in Neuron (Cambridge, Mass.) (09-12-2010)
    “…Acetylcholine release and activation of muscarinic cholinergic receptors (mAChRs) enhance synaptic plasticity in vitro and cognition and memory in vivo. Within…”
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  3. 3
    Biphasic synaptic Ca influx arising from compartmentalized electrical signals in dendritic spines

    Biphasic synaptic Ca influx arising from compartmentalized electrical signals in dendritic spines by Bloodgood, Brenda L, Giessel, Andrew J, Sabatini, Bernardo L

    Published in PLoS biology (15-09-2009)
    “…Excitatory synapses on mammalian principal neurons are typically formed onto dendritic spines, which consist of a bulbous head separated from the parent…”
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  4. 4
    Therapeutic enzyme engineering using a generative neural network

    Therapeutic enzyme engineering using a generative neural network by Giessel, Andrew, Dousis, Athanasios, Ravichandran, Kanchana, Smith, Kevin, Sur, Sreyoshi, McFadyen, Iain, Zheng, Wei, Licht, Stuart

    Published in Scientific reports (27-01-2022)
    “…Enhancing the potency of mRNA therapeutics is an important objective for treating rare diseases, since it may enable lower and less-frequent dosing. Enzyme…”
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  5. 5
    Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms

    Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms by Carter, Brett C., Giessel, Andrew J., Sabatini, Bernardo L., Bean, Bruce P.

    Published in Neuron (Cambridge, Mass.) (20-09-2012)
    “…Tetrodotoxin (TTX)-sensitive sodium channels carry large transient currents during action potentials and also “persistent” sodium current, a noninactivating…”
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  6. 6
    Boosting of synaptic potentials and spine Ca transients by the peptide toxin SNX-482 requires alpha-1E-encoded voltage-gated Ca channels

    Boosting of synaptic potentials and spine Ca transients by the peptide toxin SNX-482 requires alpha-1E-encoded voltage-gated Ca channels by Giessel, Andrew J, Sabatini, Bernardo L

    Published in PloS one (09-06-2011)
    “…The majority of glutamatergic synapses formed onto principal neurons of the mammalian central nervous system are associated with dendritic spines. Spines are…”
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  7. 7
    Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms

    Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms by Carter, Brett C., Giessel, Andrew J., Sabatini, Bernardo L., Bean, Bruce P.

    Published in Neuron (Cambridge, Mass.) (19-08-2015)
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  8. 8
    Coupling proton movement to ATP synthesis in the chloroplast ATP synthase

    Coupling proton movement to ATP synthesis in the chloroplast ATP synthase by Richter, Mark L, Samra, Hardeep S, He, Feng, Giessel, Andrew J, Kuczera, Krzysztof K

    Published in Journal of bioenergetics and biomembranes (01-12-2005)
    “…The chloroplast F(0)F(1)-ATP synthase-ATPase is a tiny rotary motor responsible for coupling ATP synthesis and hydrolysis to the light-driven electrochemical…”
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  9. 9
    Biphasic Synaptic Ca Influx Arising from Compartmentalized Electrical Signals in Dendritic Spines: e1000190

    Biphasic Synaptic Ca Influx Arising from Compartmentalized Electrical Signals in Dendritic Spines: e1000190 by Bloodgood, Brenda L, Giessel, Andrew J, Sabatini, Bernardo L

    Published in PLoS biology (01-09-2009)
    “…Excitatory synapses on mammalian principal neurons are typically formed onto dendritic spines, which consist of a bulbous head separated from the parent…”
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  10. 10
    Local, Non-linear Regulation of Synaptic Signals at Dendritic Spines of CA1 Pyramidal Cells

    Local, Non-linear Regulation of Synaptic Signals at Dendritic Spines of CA1 Pyramidal Cells by Giessel, Andrew Jacob

    Published 01-01-2010
    “…Neurons in the mammalian central nervous system communicate with each other via synapses. The dendrites of cells that receive excitatory glutamatergic input…”
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  11. 11
    Local, Non-linear Regulation of Synaptic Signals at Dendritic Spines of CA1 Pyramidal Cells

    Local, Non-linear Regulation of Synaptic Signals at Dendritic Spines of CA1 Pyramidal Cells by Giessel, Andrew Jacob

    “…Neurons in the mammalian central nervous system communicate with each other via synapses. The dendrites of cells that receive excitatory glutamatergic input…”
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