Search Results - "Giebisch, G"

Maxi-K channels contribute to urinary potassium excretion in the ROMK-deficient mouse model of Type II Bartter's syndrome and in adaptation to a high-K diet by Bailey, M.A., Cantone, A., Yan, Q., MacGregor, G.G., Leng, Q., Amorim, J.B.O., Wang, T., Hebert, S.C., Giebisch, G., Malnic, G.

“…Type II Bartter's syndrome is a hereditary hypokalemic renal salt-wasting disorder caused by mutations in the ROMK channel (Kir1.1; Kcnj1), mediating potassium…”
Get full text

Renal and extrarenal regulation of potassium by Giebisch, G., Krapf, R., Wagner, C.

“…The ISN Forefronts in Nephrology Symposium took place 8–11 September 2005 in Kartause Ittingen, Switzerland. It was dedicated to the memory of Robert W…”
Get full text

Torasemide significantly reduces thiazide-induced potassium and magnesium loss despite supra-additive natriuresis by Knauf, H, Mutschler, E, Velazquez, H, Giebisch, G

“…Background Resistance to high-dose loop diuretics can be overcome either by co-administration with thiazides or by treatment with medium-dose loop diuretics…”
Get full text

Effects of angiotensin II on electrolyte transport in the early and late distal tubule in rat kidney by Wang, T, Giebisch, G

“…We have demonstrated in previous studies that luminal administration of low doses of angiotensin II (ANG II) stimulate and high doses of ANG II inhibit fluid…”
Get full text

Mechanisms of chloride transport in the proximal tubule by Aronson, P S, Giebisch, G

“…The major fraction of filtered Cl- is reabsorbed in the proximal tubule. An important component of Cl- reabsorption is passive and paracellular, driven by the…”
Get full text

Role of luminal anion and pH in distal tubule potassium secretion by Amorim, J B O, Bailey, M A, Musa-Aziz, R, Giebisch, G, Malnic, G

“…Potassium secretory flux (J(K)) by the distal nephron is regulated by systemic and luminal factors. In the present investigation, J(K) was measured with a…”
Get more information

Renal potassium channels: Function, regulation, and structure by Giebisch, Gerhard

“…Renal potassium channels: Function, regulation and structure. Many transport functions in renal tubules depend on potassium (K) channels. Not only does K…”
Get full text

Response to ‘Reemergence of the maxi K+ as a K+ secretory channel’ by Hebert, S.-C., Giebisch, G.

Get full text

Sensitivity of a Renal K+ Channel (ROMK2) to the Inhibitory Sulfonylurea Compound Glibenclamide is Enhanced by Coexpression with the ATP-Binding Cassette Transporter Cystic Fibrosis Transmembrane Regulator by McNicholas, Carmel M., Guggino, William B., Schwiebert, Erik M., Hebert, Steven C., Giebisch, Gerhard, Egan, Marie E.

“…We demonstrate here that coexpression of ROMK2, an inwardly rectifying ATP-sensitive renal K+ channel (IKATP) with cystic fibrosis transmembrane regulator…”
Get full text

Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney by Lu, M, MacGregor, G G, Wang, W, Giebisch, G

“…We have used the patch-clamp technique to study the effects of changing extracellular ATP concentration on the activity of the small-conductance potassium…”
Get full text

ATP is a Coupling Modulator of Parallel Na,K-ATPase-K-Channel Activity in the Renal Proximal Tubule by Tsuchiya, K., Wang, W., Giebisch, G., Welling, P. A.

“…A fundamental and essential property of nearly all salt-transporting epithelia is the tight parallel coupling between the magnitude of the K-conductive pathway…”
Get full text

Dual Modulation of Renal ATP-Sensitive K+Channel by Protein Kinases A and C by Wang, Wenhui, Giebisch, Gerhard

“…A small-conductance K+channel in the apical membrane of rat cortical collecting duct (CCD) cells controls K+secretion in the kidney. Previously, we observed…”
Get full text

Angiotensin II stimulates both Na(+)-H+ exchange and Na+/HCO3- cotransport in the rabbit proximal tubule by Geibel, J, Giebisch, G, Boron, W F

“…Angiotensin II (AII) is a potent stimulus for HCO3- reabsorption in the rat proximal tubule in vivo. To determine the ionic mechanism of increased HCO3-…”
Get full text

Regulation of small-conductance K+ channel in apical membrane of rat cortical collecting tubule by Wang, W H, Schwab, A, Giebisch, G

“…We used the patch-clamp technique to study the activity and regulation of single potassium channels in the apical membrane of isolated cortical collecting…”
Get full text

Seldin and Giebisch's the Kidney: Physiology and Pathophysiology by Alpern, Robert J, Caplan, Michael J, Moe, Orson W

“…A classic nephrology reference for over 25years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this…”
Get full text

Regulation of ROMK1 K+Channel Activity Involves Phosphorylation Processes by McNicholas, Carmel M., Wang, Wenhui, Ho, Kevin, Hebert, Steven C., Giebisch, Gerhard

“…An inwardly rectifying, ATP-regulated K+channel with a distinctive molecular architecture, ROMK1, was recently cloned from rat kidney. Using patch clamp…”
Get full text

Homer Smith Award recipient--Peter Aronson by Giebisch, G

Get full text

Dual effect of adenosine triphosphate on the apical small conductance K+ channel of the rat cortical collecting duct by WENHUI WANG, GIEBISCH, G

“…We used the patch-clamp technique to study the effects of ATP on the small-conductance potassium channel in the apical membrane of rat cortical collecting duct…”
Get full text

Diuretic action of potassium channel blockers by Giebisch, G

“…The availability of specific potassium channel blockers has made it possible to examine their effects along the nephron on fluid and electrolyte excretion…”
Get full text

K(+)-induced HSP-72 expression is mediated via rapid Ca(2+) influx in renal epithelial cells by Eickelberg, O, Geibel, J, Seebach, F, Giebisch, G, Kashgarian, M

“…Pathophysiological stimuli, including hypoxia, lead to K(+) efflux from the intracellular lumen to the extracellular space, thereby increasing local tissue…”
Get more information