Search Results - "Gibson, Willietta"
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PAX2 oncogene negatively regulates the expression of the host defense peptide human beta defensin-1 in prostate cancer
Published in Molecular immunology (01-03-2009)“…Human beta defensin-1 (hBD1) is a component of the immune system which links the innate and adaptive immune responses. We have demonstrated that hBD1 induces…”
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Journal Article -
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Case Studies in Sustainability Used in an Introductory Laboratory Course to Enhance Laboratory Instruction
Published in Journal of STEM education (01-04-2017)“…This educational research seeks to develop novel laboratory modules by using Case Studies in the Science Teaching method to introduce sustainability and…”
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Journal Article -
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Functional analysis of the host defense peptide Human Beta Defensin-1: New insight into its potential role in cancer
Published in Molecular immunology (01-02-2008)“…Although it is known that innate immunity is key for protecting the body against foreign agents such as bacteria, little is known about elements of the innate…”
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Angiotensin II up-regulates PAX2 oncogene expression and activity in prostate cancer via the angiotensin II type I receptor
Published in The Prostate (01-09-2009)“…BACKGROUND Paired homeobox 2 gene (PAX2) is a transcriptional regulator, aberrantly expressed in prostate cancer cells and its down‐regulation promotes cell…”
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Abstract B67: Establishment of a high-content assay to assess the affects of gene silencing on inflammatory breast cancer cell motility
Published in Cancer epidemiology, biomarkers & prevention (01-10-2010)“…Inflammatory breast cancer (IBC) is an aggressive, highly invasive tumor with one of the worst clinical outcome among breast cancers with rapid clinical…”
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Inhibition of PAX2 expression results in alternate cell death pathways in prostate cancer cells differing in p53 status
Published in Cancer letters (18-04-2007)“…Abstract Inhibition of apoptosis is a critical pathophysiological factor that contributes to the development of prostate cancer. Recently, PAX2, a…”
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Journal Article -
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PAX2 transcriptional suppression of the putative tumor suppressor human beta defensin-1 in prostate cancer
Published 01-01-2007“…PAX2, a paired domain transcription factor involved in both embryogenesis and tumorigenesis, is aberrantly expressed in a number of cancers such as prostate…”
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Dissertation