Search Results - "Gibson, Stacy"
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Thrombin-Mediated Direct Activation of Proteinase-Activated Receptor-2: Another Target for Thrombin Signaling
Published in Molecular pharmacology (01-05-2016)“…Thrombin is known to signal to cells by cleaving/activating a G-protein-coupled family of proteinase-activated receptors (PARs). The signaling mechanism…”
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Journal Article -
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Hospital to Home Care Transitions: A Quality Improvement Initiative
Published 01-01-2023“…In hospitalized patients, the transition from hospital to home can lead to adverse events, negative outcomes, ER visits, and hospital readmissions (Backman et…”
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Dissertation -
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Abstract 2014: Genitourinary cancer-derived cells produce microenvironment proteinases that regulate proteinase activated receptors (PARs) to drive oncogenic signaling
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Background: Thrombin-triggered activation of proteinase-activated receptor-1 (PAR1) is recognized as a key stimulus for driving epithelial…”
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Journal Article -
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Proteinases, Proteinase‐Activated Receptors (PARs) and Transient Receptor Potential (TRP) Ion Channels: Driving Tumorigenesis in the Bladder Cancer Microenvironment
Published in The FASEB journal (01-04-2016)“…Abstract only Overview and hypotheses We propose that bladder cancer initiation and progression involves proteinases that become elevated in the tumour…”
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Journal Article