Search Results - "Gibson, Sheila"

Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys by Chang, Shu-Ching, Noker, Patricia E., Gorman, Gregory S., Gibson, Sheila J., Hart, Jill A., Ehresman, David J., Butenhoff, John L.

“…► Perfluorooctanesulfonate is found in biological samples from wildlife and humans. ► Pharmacokinetic parameters for PFOS in rats, mice, and monkeys were…”
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Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8 by Gorden, Keith B, Gorski, Kevin S, Gibson, Sheila J, Kedl, Ross M, Kieper, William C, Qiu, Xiaohong, Tomai, Mark A, Alkan, Sefik S, Vasilakos, John P

“…Although TLR7 and TLR8 are phylogenetically and structurally related, their relative functions are largely unknown. The role of TLR7 has been established using…”
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Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod by Gibson, Sheila J, Lindh, Jana M, Riter, Tony R, Gleason, Raymond M, Rogers, Lisa M, Fuller, Ashley E, Oesterich, JoAnn L, Gorden, Keith B, Qiu, Xiaohong, McKane, Scott W, Noelle, Randy J, Miller, Richard L, Kedl, Ross M, Fitzgerald-Bocarsly, Patricia, Tomai, Mark A, Vasilakos, John P

“…The immune response modifiers, imiquimod and resiquimod, are TLR7 agonists that induce type I interferon in numerous species, including humans. Recently, it…”
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TLR7 agonist 852A inhibition of tumor cell proliferation is dependent on plasmacytoid dendritic cells and type I IFN by Inglefield, Jon R, Dumitru, Calin Dan, Alkan, Sefik S, Gibson, Sheila J, Lipson, Kenneth E, Tomai, Mark A, Larson, Chris J, Vasilakos, John P

“…Antitumor effects of the toll-like receptor 7 (TLR7) agonist, 852A, were evaluated. Supernatants from human peripheral blood mononuclear cells (PBMC)…”
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Reconstructing the Serapeum in Alexandria from the Archaeological Evidence by McKenzie, Judith S., Gibson, Sheila, Reyes, A. T., Grimm, Günter, McKenzie, Judith S.

“…The Serapeum or Sarapeion, which contained the Temple of Serapis, was Alexandria's most important sanctuary, and one of the most famous pagan sanctuaries of…”
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Double-blind placebo-controlled trial of digoxin in symptomatic paroxysmal atrial fibrillation by Murgatroyd, F D, Gibson, S M, Baiyan, X, O'Nunain, S, Poloniecki, J D, Ward, D E, Malik, M, Camm, A J

“…Digoxin is commonly prescribed in symptomatic paroxysmal atrial fibrillation (AF) but has never been evaluated in this condition. From a multicenter registry,…”
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Apoptotic responses in squamous carcinoma and epithelial cells to small-molecule toll-like receptor agonists evaluated with automated cytometry by Inglefield, Jon R, Larson, Christopher J, Gibson, Sheila J, Lebrec, Hervé, Miller, Richard L

“…The authors describe an assay to quantitate DNA fragmentation using terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling…”
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Cytokine induction by the immunomodulators imiquimod and S-27609 by Testerman, T L, Gerster, J F, Imbertson, L M, Reiter, M J, Miller, R L, Gibson, S J, Wagner, T L, Tomai, M A

“…Imiquimod (R-837, S-26308) and the analogue S-27609 were evaluated for cytokine induction in human blood cells. Both compounds induced interferon-alpha (IFN),…”
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Water fluoridation by Jones, Graeme, Connett, Paul, Gibson, Sheila L. M., Gibson, Robin G., Holloway, P. J., McDonagh, Marian S., Kleijnen, Jos, Schmidt, T. C., Phipps, Kathy, Orwoll, Eric, Mason, Jill, Cauley, Jane, Baldwin of Bewdley, Auley, Don Mac

“…Jun 1, 2001 EDITOR-The systematic review by McDonagh et al indicates that the benefits and risks of water fluoridation balance each other in that a median of…”
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Toll-like receptor (TLR) 2–9 agonists-induced cytokines and chemokines: I. Comparison with T cell receptor-induced responses by Ghosh, Tarun K., Mickelson, Dan J., Fink, Jason, Solberg, Jonathan C., Inglefield, Jon R., Hook, Derek, Gupta, Shalley K., Gibson, Sheila, Alkan, Sefik S.

“…The cells of innate and adaptive immunity, although activated by different ligands, engage in cross talk to ensure a successful immune outcome. To better…”
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Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys: PFAA Days III A Second Special Issue on: Recent Advances in Perfluoroalkyl Acid Research by CHANG, Shu-Ching, NOKER, Patricia E, GORMAN, Gregory S, GIBSON, Sheila J, HART, Jill A, EHRESMAN, David J, BUTENHOFF, John L

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Water fluoridation and tooth decay in 5 year olds by Vemmer, Tiemo, Gibson, Sheila L. M., Gibson, Robin G., Jones, Colwyn, Taylor, Geoff, Evans, David, Whittle, Gary, Trotter, David

“…[...]Jones et al do not state whether the populations of the different wards were comparable or whether less privileged areas had a higher proportion than did…”
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Controversy continues by GIBSON, ROBIN G, GIBSON, SHEILA L.M

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Modulation of TH1 and TH2 Cytokine Production with the Immune Response Modifiers, R-848 and Imiquimod by Wagner, Tamara L., Ahonen, Cory L., Couture, Aimee M., Gibson, Sheila J., Miller, Richard L., Smith, Rose M., Reiter, Michael J., Vasilakos, John P., Tomai, Mark A.

“…Cytokines produced by antigen-presenting cells are known to affect the development and cytokine profile of T cells. The immune response modifiers imiquimod and…”
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Adjuvant Activities of Immune Response Modifier R-848: Comparison with CpG ODN by Vasilakos, John P., Smith, Rose M.A., Gibson, Sheila J., Lindh, Jana M., Pederson, Linda K., Reiter, Michael J., Smith, Michael H., Tomai, Mark A.

“…R-848 and imiquimod belong to a class of immune response modifiers that are potent inducers of cytokines, including IFN-α, TNF-α, IL-12, and IFN-γ. Many of…”
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Cytokine Induction in Hairless Mouse and Rat Skin After Topical Application of the Immune Response Modifiers Imiquimod and S-28463 by Imbertson, Linda M., Couture, Aimee M., Gibson, Sheila J., Smith, Rose M.A., Miller, Richard L., Reiter, Michael J., Wagner, Tamara L., Tomai, Mark A., Beaurline, Joseph M.

“…ALDARA (imiquimod cream 5%) recently became available for the treatment of genital and perianal warts; however, the topical mechanism of action of imiquimod is…”
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Reconstructing the Serapeum in Alexandria from the Archaeological Evidence by McKenzie, Judith S., Gibson, Sheila, Reyes, A. T., Grimm, Günter

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Dendritic Cell Maturation and Subsequent Enhanced T-Cell Stimulation Induced with the Novel Synthetic Immune Response Modifier R-848 by Ahonen, Cory L., Gibson, Sheila J., Smith, Rose M., Pederson, Linda K., Lindh, Jana M., Tomai, Mark A., Vasilakos, John P.

“…Agents that enhance dendritic cell maturation can enhance T-cell activation and therefore may improve the efficiency of vaccines or improve cellular…”
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THE NABATAEAN TEMPLE AT KHIRBET ET-TANNUR, JORDAN: VOLUME 2 — CULTIC OFFERINGS, VESSELS, AND OTHER SPECIALIST REPORTS by McKenzie, Judith S., Greene, Joseph A., Reyes, Andres T., Alexander, Catherine S., Barrett, Deirdre G., Gilmour, Brian, Healey, John F., O'Hea, Margaret, Schibille, Nadine, Schmid, Stephan G., Wetterstrom, Wilma, Kansa, Sarah Whitcher, da Costa, Kate, Degryse, Patrick, Eremin, Katherine, Gibson, Sheila, Gingerich, Owen, Khamis, Elias

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PII: S0965-2299(98)80086-1 by Gibson, Sheila L.

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