Search Results - "Gibson, Emily A"
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Three dimensional two-photon brain imaging in freely moving mice using a miniature fiber coupled microscope with active axial-scanning
Published in Scientific reports (25-05-2018)“…We present a miniature head mounted two-photon fiber-coupled microscope (2P-FCM) for neuronal imaging with active axial focusing enabled using a miniature…”
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2
Molecular layer interneurons in the cerebellum encode for valence in associative learning
Published in Nature communications (31-08-2020)“…The cerebellum plays a crucial role in sensorimotor and associative learning. However, the contribution of molecular layer interneurons (MLIs) to these…”
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3
Raman and coherent anti-Stokes Raman scattering microscopy studies of changes in lipid content and composition in hormone-treated breast and prostate cancer cells
Published in Journal of biomedical optics (01-11-2014)“…Increasing interest in the role of lipids in cancer cell proliferation and resistance to drug therapies has motivated the need to develop better tools for…”
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4
Optical vagus nerve modulation of heart and respiration via heart-injected retrograde AAV
Published in Scientific reports (11-02-2021)“…Vagus nerve stimulation has shown many benefits for disease therapies but current approaches involve imprecise electrical stimulation that gives rise to…”
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5
Optical Read-out of Neural Activity in Mammalian Peripheral Axons: Calcium Signaling at Nodes of Ranvier
Published in Scientific reports (18-07-2017)“…Current neural interface technologies have serious limitations for advanced prosthetic and therapeutic applications due primarily to their lack of specificity…”
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6
High-Throughput Examination of Fluorescence Resonance Energy Transfer-Detected Metal-Ion Response in Mammalian Cells
Published in Journal of the American Chemical Society (08-02-2012)“…Fluorescence resonance energy transfer (FRET)-based genetically encoded metal-ion sensors are important tools for studying metal-ion dynamics in live cells. We…”
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7
Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons
Published in PloS one (09-07-2013)“…The Ca(2+)-activated Cl(-) channel is considered a key constituent of odor transduction. Odorant binding to a specific receptor in the cilia of olfactory…”
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8
Three-pulse photon echo peak shift spectroscopy as a probe of flexibility and conformational heterogeneity in protein folding
Published in Chemical physics letters (01-01-2009)“…We investigate the equilibrium unfolding of Zn-cytochrome c with 3PEPS spectroscopy. The results are consistent with a two-state model. We investigate the…”
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9
Efficient reflection grisms for pulse compression and dispersion compensation of femtosecond pulses
Published in Optics letters (15-11-2006)“…Efficient reflection grisms for pulse-compression and material-dispersion compensation have been designed and demonstrated in a 40 fs, 300 microJ, 5 kHz…”
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10
High-order harmonic generation up to 250 eV from highly ionized argon
Published in Physical review letters (23-01-2004)“…We demonstrate the generation of very high-order harmonics, up to 250 eV, using argon gas. This extends by 100 eV the highest harmonics previously observed…”
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11
Multiphoton Microscopy for Ophthalmic Imaging
Published in Journal of ophthalmology (01-01-2011)“…We review multiphoton microscopy (MPM) including two-photon autofluorescence (2PAF), second harmonic generation (SHG), third harmonic generation (THG),…”
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12
Using a genetically targeted sensor to investigate the role of presenilin-1 in ER Ca2+ levels and dynamics
Published in Molecular bioSystems (01-01-2010)“…The ER plays a fundamental role in storing cellular Ca(2+), generating Ca(2+) signals, and modulating Ca(2+) in both the cytosol and mitochondria. Genetically…”
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13
Introduction to the Optics and the Brain 2023 feature issue
Published in Biomedical optics express (01-04-2024)“…A feature issue is being presented by a team of guest editors containing papers based on contributed submissions including studies presented at Optics and the…”
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Special Section Guest Editorial: Open-source neurophotonic tools for neuroscience
Published in Neurophotonics (Print) (01-07-2024)“…The editorial completes the Neurophotonics special series on open-source neurophotonic tools for neuroscience…”
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15
Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesis
Published in Nature neuroscience (01-05-2024)“…The generation of new myelin-forming oligodendrocytes in the adult central nervous system is critical for cognitive function and regeneration following injury…”
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16
Raman Microscopy Techniques to Study Lipid Droplet Composition in Cancer Cells
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Raman spectroscopy using feature selection schemes has considerable advantages over gas chromatography for the analysis of fatty acids' composition changes…”
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17
MicroLED light source for optical sectioning structured illumination microscopy
Published in Optics express (08-05-2023)“…Optical sectioning structured illumination microscopy (OS-SIM) provides optical sectioning capability in wide-field microscopy. The required illumination…”
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18
A Fiber-Coupled Stimulated Emission Depletion Microscope for Bend-Insensitive Through-Fiber Imaging
Published in Scientific reports (31-07-2019)“…We present results for a new type of fiber-coupled stimulated emission depletion (STED) microscope which uses a single fiber to transport STED and excitation…”
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19
Miniaturized fiber-coupled confocal fluorescence microscope with an electrowetting variable focus lens using no moving parts
Published in Optics letters (01-06-2015)“…We report a miniature, lightweight fiber-coupled confocal fluorescence microscope that incorporates an electrowetting variable focus lens to provide axial…”
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20
Lipid profiling using Raman and a modified support vector machine algorithm
Published in Journal of Raman spectroscopy (01-11-2021)“…Lipid droplets are dynamic organelles that play important cellular roles. They are composed of a phospholipid membrane and a core of triglycerides and sterol…”
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