Search Results - "Gibson, C F"

Porphyromonas gingivalis Sphingolipid Synthesis Limits the Host Inflammatory Response by Rocha, F.G., Moye, Z.D., Ottenberg, G., Tang, P., Campopiano, D.J., Gibson, F.C., Davey, M.E.

“…Porphyromonas gingivalis, like other bacteria belonging to the phylum Bacteroidetes, synthesizes sphingolipids (SLs). However, their exact roles in microbial…”
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Innate Immune Signaling and Porphyromonas gingivalis-accelerated Atherosclerosis by Gibson, F.C., Yumoto, H., Takahashi, Y., Chou, H.-H., Genco, C.A.

“…Periodontal diseases are a group of diseases that lead to erosion of the hard and soft tissues of the periodontium, which, in severe cases, can result in tooth…”
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Immunologic environment influences macrophage response to Porphyromonas gingivalis by Papadopoulos, G., Shaik‐Dasthagirisaheb, Y.B., Huang, N., Viglianti, G.A., Henderson, A.J., Kantarci, A., Gibson, F.C.

“…Summary Macrophages adapt both phenotypically and functionally to the cytokine balance in host tissue microenvironments. Recent studies established that…”
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Pathogen-induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell-specific innate immune inflammatory pathways by HAYASHI, C, GUDINO, C. V, GIBSON, F. C, GENCO, C. A

“…SummaryA hallmark of infection with the gram-negative pathogen Porphyromonas gingivalis is the induction of a chronic inflammatory response. P. gingivalis…”
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Aging and contribution of MyD88 and TRIF to expression of TLR pathway-associated genes following stimulation with Porphyromonas gingivalis by Shaik-Dasthagirisaheb, Y. B., Huang, N., Weinberg, E. O., Shen, S. S., Genco, C. A., Gibson III, F. C.

“…Background and Objective Periodontal disease is a highly complex chronic inflammatory disease of the oral cavity. Multiple factors influence periodontal…”
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Liver X receptors contribute to periodontal pathogen-elicited inflammation and oral bone loss by Huang, N., Shaik-Dasthagirisaheb, Y.B., LaValley, M.P., Gibson III, F.C.

“…Summary Periodontal diseases are chronic oral inflammatory diseases that are polymicrobial in nature. The presence of specific bacteria in subgingival plaque…”
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Distinct Proinflammatory Host Responses to Neisseria gonorrhoeae Infection in Immortalized Human Cervical and Vaginal Epithelial Cells by Fichorova, R N, Desai, P J, Gibson, 3rd, F C, Genco, C A

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Role of MyD88-dependent and MyD88-independent signaling in Porphyromonas gingivalis-elicited macrophage foam cell formation by Shaik-Dasthagirisaheb, Y.B., Huang, N., Baer, M.T., Gibson III, F.C.

“…Summary Clinical studies and experimental modeling identify a potential link between periodontal disease and periodontal pathogens such as Porphyromonas…”
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Prevention of Porphyromonas gingivalis-Induced Oral Bone Loss following Immunization with Gingipain R1 by GIBSON, Frank C, ATTARDO GENCO, Caroline

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Inducible nitric oxide synthase mediates bone development and P. gingivalis-induced alveolar bone loss by Gyurko, R., Shoji, H., Battaglino, R.A., Boustany, G., Gibson, F.C., Genco, C.A., Stashenko, P., Van Dyke, T.E.

“…The role of inducible nitric oxide synthase (iNOS) in bone development and bacterially induced periodontal bone loss was examined using mice with targeted…”
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Cellular Mechanism of Intraabdominal Abscess Formation by Bacteroides fragilis by Gibson, Frank C., III, Onderdonk, Andrew B, Kasper, Dennis L, Tzianabos, Arthur O

“…We investigated the cellular mechanism by which Bacteroides fragilis promotes the development of intraabdominal abscesses in experimental models of sepsis. B…”
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Fimbria-Dependent Activation of Cell Adhesion Molecule Expression in Porphyromonas gingivalis-Infected Endothelial Cells by KHLGATIAN, Mary, NASSAR, Hamdy, CHOU, Hsin-Hua, GIBSON, Frank C, ATTARDO GENCO, Caroline

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Passive transfer of poly-(1-6)-beta-glucotriosyl-(1-3)-beta-glucopyranose glucan protection against lethal infection in an animal model of intra-abdominal sepsis by CISNEROS, R. L, GIBSON, F. C, TZIANABOS, A. O, MCCALLUM, R. E

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Role for Fimbriae and Lysine-Specific Cysteine Proteinase Gingipain K in Expression of Interleukin-8 and Monocyte Chemoattractant Protein in Porphyromonas gingivalis-Infected Endothelial Cells by NASSAR, Hamdy, CHOU, Hsin-Hua, KHLGATIAN, Mary, GIBSON, Frank C, VAN DYKE, T. E, ATTARDO GENCO, Caroline

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Protection against Experimental Intraabdominal Sepsis by Two Polysaccharide Immunomodulators by Tzianabos, Arthur O., Gibson, Frank C., Cisneros, Ronald L., Kasper, Dennis L.

“…Two immunomodulating polysaccharides, poly-(1-6)-β-glucotriosyl-(1-3)-β-glucopyranose (PGG)-glucan and Bacteroides fragilis polysaccharide A (PS A), were…”
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IL-2 Mediates Protection Against Abscess Formation in an Experimental Model of Sepsis by Tzianabos, Arthur O, Russell, Pamela R, Onderdonk, Andrew B, Gibson, Frank C., III, Cywes, Colette, Chan, Melvin, Finberg, Robert W, Kasper, Dennis L

“…Little is known regarding the mechanism by which T cells control intraabdominal abscess formation. Treating animals with polysaccharide A (PS A) from…”
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The capsular polysaccharide complex of Bacteroides fragilis induces cytokine production from human and murine phagocytic cells by GIBSON, F. C, TZIANABOS, A. O, ONDERDONK, A. B

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Opsonin-independent adherence and intracellular development of Legionella pneumophila within U-937 cells by Rodgers, F G, Gibson, 3rd, F C

“…Legionella pneumophila adhered to and multiplied intracellularly in the human histiocytic lymphoma U-937 cell line. The infectious process was evaluated by…”
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Adherence of Legionella pneumophila to U-937 cells, guinea-pig alveolar macrophages, and MRC-5 cells by a novel, complement-independent binding mechanism by Gibson, 3rd, F C, Tzianabos, A O, Rodgers, F G

“…In the absence of serum, Legionella pneumophila demonstrated wash-resistant adherence to U-937 cells, primary guinea-pig alveolar macrophages, and MRC-5 cells…”
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Scavenger receptor A is expressed by macrophages in response to Porphyromonas gingivalis, and participates in TNF-α expression by Baer, M. T., Huang, N., Gibson III, F. C.

“…Introduction:  Porphyromonas gingivalis is a periodontopathic bacterium closely associated with generalized aggressive periodontal disease. Pattern recognition…”
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