Search Results - "Gibson, Alana"
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GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis
Published in eLife (13-11-2020)“…Ribosome-associated quality control pathways respond to defects in translational elongation to recycle arrested ribosomes and degrade aberrant polypeptides and…”
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Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1
Published in Human molecular genetics (01-01-2017)“…Niemann-Pick disease, type C1 (NPC1) is a heritable lysosomal storage disease characterized by a progressive neurological degeneration that causes disability…”
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Maternal immune activation modifies the course of Niemann-pick disease, type C1 in a gender specific manner
Published in Molecular genetics and metabolism (01-02-2020)“…Niemann-Pick disease, type C1 (NPC1) is a rare neurodegenerative lysosomal storage disease with a wide spectrum of clinical manifestation. Multiple genetic…”
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Improved systemic AAV gene therapy with a neurotrophic capsid in Niemann-Pick disease type C1 mice
Published in Life science alliance (01-10-2021)“…Niemann-Pick C1 disease (NPC1) is a rare, fatal neurodegenerative disease caused by mutations in , which encodes the lysosomal cholesterol transport protein…”
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Correction: GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis
Published in eLife (04-06-2021)Get full text
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Gene therapy for the treatment of Niemann-Pick disease type C1: Comparison of AAV9 to a novel serotype, AAV-PHP.B
Published in Molecular genetics and metabolism (01-02-2018)Get full text
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Improved disease amelioration with combination therapy for Niemann-Pick disease type C1
Published in Molecular genetics and metabolism (01-02-2019)Get full text
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Targeting Palbociclib-Resistant Estrogen Receptor-Positive Breast Cancer Cells via Oncolytic Virotherapy
Published in Cancers (16-05-2019)“…While clinical responses to palbociclib have been promising, metastatic breast cancer remains incurable due to the development of resistance. We generated…”
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613. A Comparison of CNS Transduction After Systemic versus Cranial Delivery of an AAV2/9 CamKII Promoter-eGFP Vector in Mice
Published in Molecular therapy (01-05-2016)Get full text
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