Search Results - "Gibe, Romelo"

Design and synthesis of novel bone-targeting dual-action pro-drugs for the treatment and reversal of osteoporosis by Arns, Steve, Gibe, Romelo, Moreau, Anne, Monzur Morshed, M., Young, Robert N.

“…Dual-action pro-drugs (e.g. 9) target and bind to bone in vivo and slowly release the bone resorption inhibitor, alendronic acid (1) and the bone growth…”
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Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin by Nicolaou, K. C, Frederick, Michael O, Burtoloso, Antonio C. B, Denton, Ross M, Rivas, Fatima, Cole, Kevin P, Aversa, Robert J, Gibe, Romelo, Umezawa, Taiki, Suzuki, Takahiro

“…As the largest secondary metabolite to be discovered as of yet, the polyether marine neurotoxin maitotoxin constitutes a major structural and synthetic…”
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Convenient Preparation of Indolyl Malonates via Carbenoid Insertion by Gibe, Romelo, Kerr, Michael A

“…Indoles, when treated with methyldiazomalonate under catalysis by rhodium(II)acetate, undergo C−H and N−H insertion reactions regioselectively depending on the…”
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Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore by MCNULTY, James, MAO, Justin, GIBE, Romelo, MO, Ruowei, WOLF, Sonja, PETTIT, George R, HERALD, Delbert L, BOYD, Michael R

“…Two deoxy-analogues of the anticancer/antiviral agent pancratistatin containing functionality complementary to the minimum structural pharmacophore were…”
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Furfuryl alcohol is a precursor for furfurylthiol in coffee by Cerny, Christoph, Schlichtherle-Cerny, Hedwig, Gibe, Romelo, Yuan, Yuan

“…•The aroma precursor role of furfuryl alcohol was studied by coffee in-bean experiments.•Spiking coffee beans with furfuryl alcohol increased the furfurylthiol…”
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Chiral Pool Based Synthesis of Platensimycin by Nicolaou, K.C, Pappo, Doron, Tsang, Kit Y, Gibe, Romelo, Chen, David Y.-K

“…Extensive pharming: An expedient entry into the tetracycle 2, a late‐stage synthetic intermediate en route to the broad‐spectrum antibiotic (−)‐platensimycin…”
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Design and synthesis of novel bone-targeting dual-action pro-drugs for the treatment and reversal of osteoporosis: The Chemistry Biology Interface by ARNS, Steve, GIBE, Romelo, MOREAU, Anne, MONZUR MORSHED, M, YOUNG, Robert N

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Indolophanetetrayne Cobalt Complexes via Nicholas Reactions by Gibe, Romelo, Green, James R, Davidson, Greg

“…Indole N-substituted diyne tetracobalt complexes (4) undergo a Lewis acid mediated dimerization−cyclization reaction through the indole 3-position to afford…”
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Synthesis of cyclophanetetrayne complexes from bis(propargyldicobalt) dication equivalents by Gibe, Romelo, Green, James R

“…Nicholas reactions of the p-phenyl linked bis(propargyl acetate) complex (3a) with electron rich arenes give cyclophanetetrayne complexes (5). The use of…”
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Mono- and disubstitutions of (hepta-2,5-diyne-1,7-diol) bis(dicobalt) derivatives - Selectivity in Nicholas reactions1 by Guo, Richard, Gibe, Romelo, Green, James R

“…Bis(hexacarbonyldicobalt) complexes of benzyl ether - methyl ether or benzyl ether - acetate derivatives of hepta-2,5-diyne-1,7-diols undergo selective…”
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A Chiral Pool Based Synthesis of Platensimycin by Nicolaou, K. C., Pappo, Doron, Tsang, Kit Y., Gibe, Romelo, Chen, David Y.-K.

“…Ein direkter Weg führt zu dem Tetracyclus 2, einer späten Zwischenstufe in der Synthese des Breitbandantibiotikums (−)‐Platensimycin (1). Zu diesem Zweck wird…”
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Mono- and disubstitutions of (hepta-2,5-diyne-1,7-diol) bis(dicobalt) derivatives — Selectivity in Nicholas reactions by Guo, Richard, Gibe, Romelo, Green, James R

“…Bis(hexacarbonyldicobalt) complexes of benzyl ether – methyl ether or benzyl ether – acetate derivatives of hepta-2,5-diyne-1,7-diols undergo selective…”
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I. Preparation of indolyl malonates via carbenoid insertion. II. Studies towards the synthesis of Quebrachamine and Aspidospermidine by Gibe, Romelo B

“…Indoles, when treated with methyldiazomalonate under catalysis by rhodium(II)acetate, undergo C-H and N-H insertion reactions regioselectively depending on the…”
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I. Preparation of indolyl malonates via carbenoid insertion. II. Studies towards the synthesis of Quebrachamine and Aspidospermidine by Gibe, Romelo B

“…Indoles, when treated with methyldiazomalonate under catalysis by rhodium(II)acetate, undergo C-H and N-H insertion reactions regioselectively depending on the…”
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A Chiral Pool Based Synthesis of Platensimycin by Nicolaou, K. C., Pappo, Doron, Tsang, Kit Y., Gibe, Romelo, Chen, David Y.‐K.

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