Search Results - "Gibbs, R. J."

Sotatercept for the Treatment of Pulmonary Arterial Hypertension by Humbert, Marc, McLaughlin, Vallerie, Gibbs, J. Simon R, Gomberg-Maitland, Mardi, Hoeper, Marius M, Preston, Ioana R, Souza, Rogerio, Waxman, Aaron, Escribano Subias, Pilar, Feldman, Jeremy, Meyer, Gisela, Montani, David, Olsson, Karen M, Manimaran, Solaiappan, Barnes, Jennifer, Linde, Peter G, de Oliveira Pena, Janethe, Badesch, David B

“…Patients with pulmonary arterial hypertension were randomly assigned to receive sotatercept at a dose of 0.3 mg per kilogram or 0.7 mg per kilogram or placebo,…”
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Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model by Hoeper, Marius M, Kramer, Tilmann, Pan, Zixuan, Eichstaedt, Christina A, Spiesshoefer, Jens, Benjamin, Nicola, Olsson, Karen M, Meyer, Katrin, Vizza, Carmine Dario, Vonk-Noordegraaf, Anton, Distler, Oliver, Opitz, Christian, Gibbs, J Simon R, Delcroix, Marion, Ghofrani, H Ardeschir, Huscher, Doerte, Pittrow, David, Rosenkranz, Stephan, Grünig, Ekkehard

“…The 2015 European pulmonary hypertension (PH) guidelines propose a risk stratification strategy for patients with pulmonary arterial hypertension (PAH). Low-,…”
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The changing landscape of pulmonary arterial hypertension and implications for patient care by Hoeper, Marius M, Simon R Gibbs, J

“…Registries have provided a wealth of information on the clinical and disease characteristics of patients living with pulmonary arterial hypertension (PAH)…”
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Pulmonary Hypertension Due to Left Heart Diseases by Vachiéry, Jean-Luc, MD, Adir, Yochai, MD, MHA, Barberà, Joan Albert, MD, PhD, Champion, Hunter, MD, Coghlan, John Gerard, MD, Cottin, Vincent, MD, PhD, De Marco, Teresa, MD, Galiè, Nazzareno, MD, Ghio, Stefano, MD, Gibbs, J. Simon R., MD, Martinez, Fernando, MD, Semigran, Marc, MD, Simonneau, Gerald, MD, Wells, Athol, MD, MBSHB, Seeger, Werner, MD, PhD

“…Pulmonary hypertension (PH), a common complication of left heart diseases (LHD), negatively impacts symptoms, exercise capacity, and outcome. Although the true…”
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Effect of altitude on the heart and the lungs by BÄRTSCH, Peter, GIBBS, J. Simon R

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emPHasis-10: development of a health-related quality of life measure in pulmonary hypertension by YORKE, Janelle, CORRIS, Paul, GAINE, Sean, GIBBS, J. Simon R, KIELY, David G, HARRIES, Carl, POLLOCK, Val, ARMSTRONG, Lain

“…The aim of this study was to develop a measure of the impact of pulmonary hypertension (PH) on health-related quality of life (HRQoL) as there is a need for a…”
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Red cell distribution width outperforms other potential circulating biomarkers in predicting survival in idiopathic pulmonary arterial hypertension by Rhodes, Christopher J, Wharton, John, Howard, Luke S, Gibbs, J Simon R, Wilkins, Martin R

“…In addition to N-terminal pro-brain natriuretic peptide (NT-proBNP), red cell distribution width (RDW), growth differentiation factor (GDF)-15, interleukin…”
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Connective Tissue Disease-associated Pulmonary Arterial Hypertension in the Modern Treatment Era by Condliffe, Robin, Kiely, David G, Peacock, Andrew J, Corris, Paul A, Gibbs, J. Simon R, Vrapi, Florenc, Das, Clare, Elliot, Charlie A, Johnson, Martin, DeSoyza, Julia, Torpy, Chantal, Goldsmith, Kim, Hodgkins, Denise, Hughes, Rodney J, Pepke-Zaba, Joanna, Coghlan, J. Gerry

“…Pulmonary arterial hypertension in association with connective tissue disease (CTD-PAH) has historically had a poor prognosis, with a 1-year survival rate…”
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Updated Evidence-Based Treatment Algorithm in Pulmonary Arterial Hypertension by Barst, Robyn J., MD, Gibbs, J. Simon R., MD, Ghofrani, Hossein A., MD, Hoeper, Marius M., MD, McLaughlin, Vallerie V., MD, Rubin, Lewis J., MD, Sitbon, Olivier, MD, Tapson, Victor F., MD, Galiè, Nazzareno, MD

“…Uncontrolled and controlled clinical trials with different compounds and procedures are reviewed to define the risk-benefit profiles for therapeutic options in…”
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Deep-learning cardiac motion analysis for human survival prediction by Bello, Ghalib A., Dawes, Timothy J. W., Duan, Jinming, Biffi, Carlo, de Marvao, Antonio, Howard, Luke S. G. E., Gibbs, J. Simon R., Wilkins, Martin R., Cook, Stuart A., Rueckert, Daniel, O’Regan, Declan P.

“…Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimizing the interpretation of dynamic…”
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Pulmonary Hypertension in Patients with Chronic Fibrosing Idiopathic Interstitial Pneumonias by Hoeper, Marius M, Behr, Juergen, Held, Matthias, Grunig, Ekkehard, Vizza, C Dario, Vonk-Noordegraaf, Anton, Lange, Tobias J, Claussen, Martin, Grohé, Christian, Klose, Hans, Olsson, Karen M, Zelniker, Thomas, Neurohr, Claus, Distler, Oliver, Wirtz, Hubert, Opitz, Christian, Huscher, Doerte, Pittrow, David, Gibbs, J Simon R

“…Pulmonary hypertension (PH) is a common finding in patients with chronic fibrosing idiopathic interstitial pneumonias (IIP). Little is known about the response…”
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Differences in Ventilatory Inefficiency Between Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension by Zhai, Zhenguo, PhD, Murphy, Kevin, PhD, Tighe, Hannah, BSc, Wang, Chen, PhD, FCCP, Wilkins, Martin R., PhD, Gibbs, J. Simon R., MD, Howard, Luke S., DPhil

“…Background Measures of ventilatory efficiency during cardiopulmonary exercise testing (CPX) are increasingly being used as prognostic markers in heart failure…”
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End Points and Clinical Trial Design in Pulmonary Arterial Hypertension by McLaughlin, Vallerie V., MD, Badesch, David B., MD, Delcroix, Marion, MD, PhD, Fleming, Thomas R., PhD, Gaine, Sean P., MD, PhD, Galiè, Nazzareno, MD, Gibbs, J. Simon R., MD, Kim, Nick H., MD, Oudiz, Ronald J., MD, Peacock, Andrew, MD, Provencher, Steeve, MD, MSc, Sitbon, Olivier, MD, Tapson, Victor F., MD, Seeger, Werner, MD

“…New and emerging therapies might provide benefit in patients with pulmonary arterial hypertension. Their efficacy and safety will be compared with existing…”
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Improved Outcomes in Medically and Surgically Treated Chronic Thromboembolic Pulmonary Hypertension by Condliffe, Robin, Kiely, David G, Gibbs, J. Simon R, Corris, Paul A, Peacock, Andrew J, Jenkins, David P, Hodgkins, Denise, Goldsmith, Kim, Hughes, Rodney J, Sheares, Karen, Tsui, Steven S. L, Armstrong, Iain J, Torpy, Chantal, Crackett, Rachel, Carlin, Christopher M, Das, Clare, Coghlan, J. Gerry, Pepke-Zaba, Joanna

“…The management of chronic thromboembolic pulmonary hypertension (CTEPH) has changed over recent years with the growth of pulmonary endarterectomy surgery and…”
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Cardiovascular magnetic resonance in pulmonary hypertension by Bradlow, William M, Gibbs, J Simon R, Mohiaddin, Raad H

“…Pulmonary hypertension represents a group of conditions characterized by higher than normal pulmonary artery pressures. Despite improved treatments, outcomes…”
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Echocardiographic assessment of pulmonary hypertension: standard operating procedure by Howard, Luke S, Grapsa, Julia, Dawson, David, Bellamy, Michael, Chambers, John B, Masani, Navroz D, Nihoyannopoulos, Petros, Simon R Gibbs, J

“…Patients with suspected pulmonary hypertension (PH) should be evaluated using a multimodality approach to ensure that they receive a correct diagnosis. The…”
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Simvastatin as a Treatment for Pulmonary Hypertension Trial by WILKINS, Martin R, ALI, Omar, GIBBS, J. Simon R, BRADLOW, William, WHARTON, John, TAEGTMEYER, Anne, RHODES, Christopher J, GHOFRANI, Hossein A, HOWARD, Luke, NIHOYANNOPOULOS, Petros, MOHIADDIN, Raad H

“…In animal models of pulmonary hypertension, simvastatin has been shown to reduce pulmonary artery pressure and induce regression of associated right…”
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Aberrant Chloride Intracellular Channel 4 Expression Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension by Wojciak-Stothard, Beata, Abdul-Salam, Vahitha B, Lao, Ka Hou, Tsang, Hilda, Irwin, David C, Lisk, Christina, Loomis, Zoe, Stenmark, Kurt R, Edwards, John C, Yuspa, Stuart H, Howard, Luke S, Edwards, Robert J, Rhodes, Christopher J, Gibbs, J. Simon R, Wharton, John, Zhao, Lan, Wilkins, Martin R

“…BACKGROUND—Chloride intracellular channel 4 (CLIC4) is highly expressed in the endothelium of remodeled pulmonary vessels and plexiform lesions of patients…”
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Prognostic and aetiological factors in chronic thromboembolic pulmonary hypertension by Condliffe, R, Kiely, D. G, Gibbs, J. S. R, Corris, P. A, Peacock, A. J, Jenkins, D. P, Goldsmith, K, Coghlan, J. G, Pepke-Zaba, J

“…Several prognostic variables have previously been identified in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Specific medical…”
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Diagnosis of pulmonary hypertension by Frost, Adaani, Badesch, David, Gibbs, J Simon R, Gopalan, Deepa, Khanna, Dinesh, Manes, Alessandra, Oudiz, Ronald, Satoh, Toru, Torres, Fernando, Torbicki, Adam

“…A revised diagnostic algorithm provides guidelines for the diagnosis of patients with suspected pulmonary hypertension, both prior to and following referral to…”
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