Search Results - "Gibbs, Clarence J."

The 14-3-3 Brain Protein in Cerebrospinal Fluid as a Marker for Transmissible Spongiform Encephalopathies by Hsich, Gary, Kenney, Kimbra, Gibbs, Clarence J, Lee, Kelvin H, Harrington, Michael G

“…The transmissible spongiform encephalopathies constitute a group of uniformly fatal neurodegenerative diseases. These diseases include Creutzfeldt–Jakob…”
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Phenotypic Variability of Gerstmann-Straussler-Scheinker Disease is Associated with Prion Protein Heterogeneity by Piccardo, Pedro, Dlouhy, Stephen R, Lievens, Patricia M. J, Young, Katherine, Bird, Thomas D, Nochlin, David, Dickson, Dennis W, Vinters, Harry V, Zimmerman, Thomas R, Mackenzie, Ian R. A, Kish, Stephen J, Ang, Lee-Cyn, De Carli, Charles, Pocchiari, Maurizio, Brown, Paul, Gibbs, Clarence J, Gajdusek, D Carlton, Bugiani, Orso, Ironside, James, Tagliavini, Fabrizio, Ghetti, Bernardino

“…Gerstmann-StrSussler-Scheinker disease (GSS), a cerebello-pyramidal syndrome associated with dementia and caused by mutations in the priori protein gene…”
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scrapie Amyloid (Prion) Protein Has the Conformational Characteristics of an Aggregated Molten Globule Folding Intermediate by Safar, Jiri, Roller, Peter P, Gajdusek, D. Carleton, Gibbs, Clarence J

“…The scrapie amyloid (prion) protein (PrP27-30) is a host-derived component of the infectious scrapie agent; the potential to replicate, propagate, and form…”
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Creutzfeldt–Jakob Disease and Related Transmissible Spongiform Encephalopathies by Johnson, Richard T, Gibbs, Clarence J

“…Until 30 years ago, Creutzfeldt–Jakob disease was an obscure form of dementia unknown to most physicians. The name is now familiar to the medical community as…”
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New studies on the heat resistance of hamster-adapted scrapie agent: Threshold survival after ashing at 600°C suggests an inorganic template of replication by Brown, P.

“…One-gram samples from a pool of crude brain tissue from hamsters infected with the 263K strain of hamster-adapted scrapie agent were placed in covered…”
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Intraneuronal Aluminum Accumulation in Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia of Guam by Perl, Daniel P., Gajdusek, D. Carleton, Garruto, Ralph M., Yanagihara, Richard T., Gibbs, Clarence J.

“…Scanning electron microscopy with energy-dispersive x-ray spectrometry was used to analyze the elemental content of neurofibrillary tangle (NFT)-bearing and…”
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Secondary structure of proteins associated in thin films by Safar, J, Roller, P P, Ruben, G C, Gajdusek, D C, Gibbs, Jr, C J

“…The solid state secondary structure of myoglobin, RNase A, concanavalin A (Con A), poly(L-lysine), and two linear heterooligomeric peptides were examined by…”
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Creutzfeldt-Jakob Disease Infectivity of Growth Hormone Derived from Human Pituitary Glands by Gibbs, Clarence J, Asher, David M, Brown, Paul W, Fradkin, Judith E, Gajdusek, D. Carleton

“…To the Editor: As part of a comprehensive evaluation of the risk of Creutzfeldt-Jakob disease in recipients of native human growth hormone (GH), we inoculated…”
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Clinical and pathological features and laboratory confirmation of Creutzfeldt-Jakob disease in a recipient of pituitary-derived human growth hormone by Gibbs, Jr, C J, Joy, A, Heffner, R, Franko, M, Miyazaki, M, Asher, D M, Parisi, J E, Brown, P W, Gajdusek, D C

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Absence of measles, mumps, and rubella viral genomic sequences from multiple sclerosis brain tissue by polymerase chain reaction by Godec, M S, Asher, D M, Murray, R S, Shin, M L, Greenham, L W, Gibbs, Jr, C J, Gajdusek, D C

“…We tested for measles, mumps, and rubella viruses in multiple sclerosis by polymerase chain reaction (PCR). Using RNA extracted from 19 multiple sclerosis and…”
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Creutzfeldt-Jakob disease: patterns of worldwide occurrence and the significance of familial and sporadic clustering by Masters, C L, Harris, J O, Gajdusek, D C, Gibbs, Jr, C J, Bernoulli, C, Asher, D M

“…The worldwide epidemiology of Creutzfeldt-Jakob disease (CJD) is presented from an analysis of 1,435 patients. In the United States, the average annual…”
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Creutzfeldt-Jakob disease of long duration: clinicopathological characteristics, transmissibility, and differential diagnosis by Brown, P, Rodgers-Johnson, P, Cathala, F, Gibbs, Jr, C J, Gajdusek, D C

“…Five to 10% of patients with Creutzfeldt-Jakob disease have a clinical course that extends for 2 years or more. In the present series 33 (9%) of 357…”
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Intrathecal synthesis of IgG antibodies to HTLV-I supports an etiological role for HTLV-I in tropical spastic paraparesis by Ceroni, M, Piccardo, P, Rodgers-Johnson, P, Mora, C, Asher, D M, Gajdusek, D C, Gibbs, Jr, C J

“…High titers of antibody to human T-lymphotropic virus type I (HTLV-I) have been reported in the sera and cerebrospinal fluids of patients with tropical spastic…”
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Chemical disinfection of Creutzfeldt-Jakob disease virus by Brown, P, Gibbs, Jr, C J, Amyx, H L, Kingsbury, D T, Rohwer, R G, Sulima, M P, Gajdusek, D C

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The role of HTLV-I in tropical spastic paraparesis in Jamaica by Rodgers-Johnson, P, Morgan, O S, Mora, C, Sarin, P, Ceroni, M, Piccardo, P, Garruto, R M, Gibbs, Jr, C J, Gajdusek, D C

“…We report clinical and laboratory investigations of 47 native-born Jamaican patients with endemic tropical spastic paraparesis and of 1 patient with tropical…”
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Neuronal degeneration and neurofilament accumulation in the trigeminal ganglia in Creutzfeldt-Jakob disease by Guiroy, D C, Shankar, S K, Gibbs, Jr, C J, Messenheimer, J A, Das, S, Gajdusek, D C

“…We report the pathological and immunohistochemical changes in the first-order neurons in the trigeminal ganglia in Creutzfeldt-Jakob disease (CJD)…”
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Experimental Subacute Spongiform Virus Encephalopathies in Primates and Other Laboratory Animals by Gibbs, Clarence J., Gajdusek, D. Carleton

“…The host range of subacute spongiform virus encephalopathies is described. The asymptomatic incubation period and the duration of the illnesses in various…”
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Early induction of protein nexin-I in scrapie by Cavallaro, Sebastiano, Gibbs, Clarence J, Pergami, Paola

“…WE used RNA fingerprinting by arbitrary primed PCR to identify genes whose expression is up-regulated in the brain of hamsters affected by prion disease. One…”
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Novel PRNP sequence variant associated with familial encephalopathy by Cervenáková, Larisa, Buetefisch, Cathrin, Lee, Hee-Suk, Taller, Inna, Stone, Gary, Gibbs Jr, Clarence J., Brown, Paul, Hallett, Mark, Goldfarb, Lev G.

“…Human transmissible spongiform encephalopathies (TSEs) are a group of chronic progressive neurodegenerative disorders that may be hereditary, infectious, or…”
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Transmission of Two Subacute Spongiform Encephalopathies of Man (Kuru and Creutzfeldt-Jakob Disease) to New World Monkeys by GAJDUSEK, D. CARLETON, GIBBS, CLARENCE J

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