Search Results - "Gibbs, Bettine E"
-
1
A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation
Published in Journal of medicinal chemistry (14-01-2021)“…Mitochondrial dysfunction is an underlying pathology in numerous diseases. Delivery of diagnostic and therapeutic cargo directly into mitochondria is a…”
Get full text
Journal Article -
2
Dissecting OGT's TPR domain to identify determinants of cellular function
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-2024)“…O-GlcNAc transferase (OGT) is an essential mammalian enzyme that glycosylates myriad intracellular proteins and cleaves the transcriptional coregulator Host…”
Get full text
Journal Article -
3
Molecular Targeting and Inactivation of Glutaminase and CDK4/6 in Mantle Cell Lymphoma
Published in The FASEB journal (01-04-2018)“…Mantle Cell Lymphoma (MCL) is an aggressive B‐cell non‐Hodgkin's lymphoma (NHL) subtype that accounts for 7% of all NHL cases. Upon relapse, standard salvage…”
Get full text
Journal Article -
4
Abstract 5418: Deciphering the dynamics of alternative pre-mRNA processing of glutaminase in metastatic ovarian cancer
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract The chronically proliferative cancer phenotype requires metabolic reprogramming to meet the increased energy and biosynthetic demands of rapid cell…”
Get full text
Journal Article