Search Results - "Gibbs, A."

The Human Genome Project changed everything by Gibbs, Richard A.

“…Thirty years on from the launch of the Human Genome Project, Richard Gibbs reflects on the promises that this voyage of discovery bore. Its success should be…”
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Comparative primate genomics: emerging patterns of genome content and dynamics by Rogers, Jeffrey, Gibbs, Richard A.

“…Key Points Whole-genome assemblies are now available for all the great apes and several other non-human primate species. The published analyses document…”
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Human Genome Sequencing in Health and Disease by Gonzaga-Jauregui, Claudia, Lupski, James R, Gibbs, Richard A

“…Following the "finished," euchromatic, haploid human reference genome sequence, the rapid development of novel, faster, and cheaper sequencing technologies is…”
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Temporal development of the gut microbiome in early childhood from the TEDDY study by Stewart, Christopher J., Ajami, Nadim J., O’Brien, Jacqueline L., Hutchinson, Diane S., Smith, Daniel P., Wong, Matthew C., Ross, Matthew C., Lloyd, Richard E., Doddapaneni, HarshaVardhan, Metcalf, Ginger A., Muzny, Donna, Gibbs, Richard A., Vatanen, Tommi, Huttenhower, Curtis, Xavier, Ramnik J., Rewers, Marian, Hagopian, William, Toppari, Jorma, Ziegler, Anette-G., She, Jin-Xiong, Akolkar, Beena, Lernmark, Ake, Hyoty, Heikki, Vehik, Kendra, Krischer, Jeffrey P., Petrosino, Joseph F.

“…The development of the microbiome from infancy to childhood is dependent on a range of factors, with microbial–immune crosstalk during this time thought to be…”
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Global maps of twenty-first century forest carbon fluxes by Harris, Nancy L., Gibbs, David A., Baccini, Alessandro, Birdsey, Richard A., de Bruin, Sytze, Farina, Mary, Fatoyinbo, Lola, Hansen, Matthew C., Herold, Martin, Houghton, Richard A., Potapov, Peter V., Suarez, Daniela Requena, Roman-Cuesta, Rosa M., Saatchi, Sassan S., Slay, Christy M., Turubanova, Svetlana A., Tyukavina, Alexandra

“…Managing forests for climate change mitigation requires action by diverse stakeholders undertaking different activities with overlapping objectives and spatial…”
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Impact of COVID-19 lockdown and link to women and children's experiences of violence in the home in South Africa by Mahlangu, P, Gibbs, A, Shai, N, Machisa, M, Nunze, N, Sikweyiya, Y

“…Evidence on the impact of COVID-19 and lockdown remains at an early stage. There is limited research about the impact of hard lockdown restrictions on…”
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Electrocardiographic manifestations of severe hyperkalemia by Littmann, Laszlo, Gibbs, Michael A.

“…Severe hyperkalemia is a hazardous condition that warrants urgent intervention. In critically ill patients, the electrocardiogram (ECG) can be the most…”
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Strain Control of Fermiology and Many-Body Interactions in Two-Dimensional Ruthenates by Burganov, B, Adamo, C, Mulder, A, Uchida, M, King, P D C, Harter, J W, Shai, D E, Gibbs, A S, Mackenzie, A P, Uecker, R, Bruetzam, M, Beasley, M R, Fennie, C J, Schlom, D G, Shen, K M

“…Here we demonstrate how the Fermi surface topology and quantum many-body interactions can be manipulated via epitaxial strain in the spin-triplet…”
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Large-Eddy Simulation of the Atmospheric Boundary Layer by Stoll, Rob, Gibbs, Jeremy A., Salesky, Scott T., Anderson, William, Calaf, Marc

“…Over the last 50 years the large-eddy simulation (LES) technique has developed into one of the most prominent numerical tools used to study transport processes…”
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High-Resolution Photoemission on Sr2RuO4 Reveals Correlation-Enhanced Effective Spin-Orbit Coupling and Dominantly Local Self-Energies by Tamai, A, Zingl, M, Rozbicki, E, Cappelli, E, Riccò, S, de la Torre, A, S. McKeown Walker, Bruno, F Y, King, P D C, Meevasana, W, Shi, M, Radović, M, Plumb, N C, Gibbs, A S, Mackenzie, A P, Berthod, C, Strand, H U R, Kim, M, Georges, A, Baumberger, F

“…We explore the interplay of electron-electron correlations and spin-orbit coupling in the model Fermi liquidSr2RuO4using laser-based angle-resolved…”
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Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population by Comuzzie, Anthony G, Cole, Shelley A, Laston, Sandra L, Voruganti, V. Saroja, Haack, Karin, Gibbs, Richard A, Butte, Nancy F, Crawford, Dana C

“…Genetic variants responsible for susceptibility to obesity and its comorbidities among Hispanic children have not been identified. The VIVA LA FAMILIA Study…”
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Truvari: refined structural variant comparison preserves allelic diversity by English, Adam C, Menon, Vipin K, Gibbs, Richard A, Metcalf, Ginger A, Sedlazeck, Fritz J

“…The fundamental challenge of multi-sample structural variant (SV) analysis such as merging and benchmarking is identifying when two SVs are the same. Common…”
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First Results from the Catalina Real-Time Transient Survey by Drake, A. J, Djorgovski, S. G, Mahabal, A, Beshore, E, Larson, S, Graham, M. J, Williams, R, Christensen, E, Catelan, M, Boattini, A, Gibbs, A, Hill, R, Kowalski, R

“…We report on the results from the first six months of the Catalina Real-Time Transient Survey (CRTS). In order to search for optical transients (OTs) with…”
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Mind the gap: upgrading genomes with Pacific Biosciences RS long-read sequencing technology by English, Adam C, Richards, Stephen, Han, Yi, Wang, Min, Vee, Vanesa, Qu, Jiaxin, Qin, Xiang, Muzny, Donna M, Reid, Jeffrey G, Worley, Kim C, Gibbs, Richard A

“…Many genomes have been sequenced to high-quality draft status using Sanger capillary electrophoresis and/or newer short-read sequence data and whole genome…”
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Molecular Findings Among Patients Referred for Clinical Whole-Exome Sequencing by Yang, Yaping, Muzny, Donna M, Xia, Fan, Niu, Zhiyv, Person, Richard, Ding, Yan, Ward, Patricia, Braxton, Alicia, Wang, Min, Buhay, Christian, Veeraraghavan, Narayanan, Hawes, Alicia, Chiang, Theodore, Leduc, Magalie, Beuten, Joke, Zhang, Jing, He, Weimin, Scull, Jennifer, Willis, Alecia, Landsverk, Megan, Craigen, William J, Bekheirnia, Mir Reza, Stray-Pedersen, Asbjorg, Liu, Pengfei, Wen, Shu, Alcaraz, Wendy, Cui, Hong, Walkiewicz, Magdalena, Reid, Jeffrey, Bainbridge, Matthew, Patel, Ankita, Boerwinkle, Eric, Beaudet, Arthur L, Lupski, James R, Plon, Sharon E, Gibbs, Richard A, Eng, Christine M

“…IMPORTANCE: Clinical whole-exome sequencing is increasingly used for diagnostic evaluation of patients with suspected genetic disorders. OBJECTIVE: To perform…”
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Transmission event of SARS-CoV-2 delta variant reveals multiple vaccine breakthrough infections by Farinholt, Timothy, Doddapaneni, Harsha, Qin, Xiang, Menon, Vipin, Meng, Qingchang, Metcalf, Ginger, Chao, Hsu, Gingras, Marie-Claude, Avadhanula, Vasanthi, Farinholt, Paige, Agrawal, Charu, Muzny, Donna M, Piedra, Pedro A, Gibbs, Richard A, Petrosino, Joseph

“…This study aims to identify the causative strain of SARS-CoV-2 in a cluster of vaccine breakthroughs. Vaccine breakthrough by a highly transmissible SARS-CoV-2…”
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Clan Genomics and the Complex Architecture of Human Disease by Lupski, James R., Belmont, John W., Boerwinkle, Eric, Gibbs, Richard A.

“…Human diseases are caused by alleles that encompass the full range of variant types, from single-nucleotide changes to copy-number variants, and these…”
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MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation by Gibbs, A, Leeansyah, E, Introini, A, Paquin-Proulx, D, Hasselrot, K, Andersson, E, Broliden, K, Sandberg, J K, Tjernlund, A

“…The female genital tract (FGT) mucosa is a critically important site for immune defense against microbes. Mucosal-associated invariant T (MAIT) cells are an…”
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Diversity and evolution of the transposable element repertoire in arthropods with particular reference to insects by Petersen, Malte, Armisén, David, Gibbs, Richard A, Hering, Lars, Khila, Abderrahman, Mayer, Georg, Richards, Stephen, Niehuis, Oliver, Misof, Bernhard

“…Transposable elements (TEs) are a major component of metazoan genomes and are associated with a variety of mechanisms that shape genome architecture and…”
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Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation by Posey, Jennifer E, Harel, Tamar, Liu, Pengfei, Rosenfeld, Jill A, James, Regis A, Coban Akdemir, Zeynep H, Walkiewicz, Magdalena, Bi, Weimin, Xiao, Rui, Ding, Yan, Xia, Fan, Beaudet, Arthur L, Muzny, Donna M, Gibbs, Richard A, Boerwinkle, Eric, Eng, Christine M, Sutton, V. Reid, Shaw, Chad A, Plon, Sharon E, Yang, Yaping, Lupski, James R

“…Of over 7000 patients referred to a diagnostic laboratory, 28% had diagnoses based on DNA sequencing, 5% of whom had two or more diagnoses. Their phenotypes…”
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