Search Results - "Gibbons, Peter L"

Mechanism-Based Model of Parasite Growth and Dihydroartemisinin Pharmacodynamics in Murine Malaria by PATEL, Kashyap, BATTY, Kevin T, MOORE, Brioni R, GIBBONS, Peter L, BULITTA, Jürgen B, KIRKPATRICK, Carl M

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Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model by Patel, Kashyap, Batty, Kevin T, Moore, Brioni R, Gibbons, Peter L, Kirkpatrick, Carl M

“…To develop a mechanism-based model that describes the time course of the malaria parasite in infected mice receiving a combination therapy regimen of…”
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Short Report : Pharmacokinetics of Dihydroartemisinin in a Murine Malaria Model by BATTY, Kevin T, GIBBONS, Peter L, DAVIS, Timothy M. E, ILETT, Kenneth F

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Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin by Gibbons, Peter L., Batty, Kevin T., Barrett, P. Hugh R., Davis, Timothy M.E., Ilett, Kenneth F.

“…Antimalarial treatment strategies based on in vitro studies are limited by the paucity of pharmacodynamic information for dosage regimen design. We postulated…”
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Pharmacokinetics of Dihydroartemisinin in a Murine Malaria Model by Batty, Kevin T, Gibbons, Peter L, Davis, Timothy M. E, Ilett, Kenneth F

“…Pharmacokinetic properties of dihydroartemisinin (DHA) were determined in mice given 100 mg/kg intraperitoneal DHA. Half-life, CL/F, and V/F were 25 min, 61.3…”
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