Search Results - "Gibbons, Joyce Sweeney"

Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways by Williams, Caroline G, Gibbons, Joyce Sweeney, Keiffer, Timothy R, Luthra, Priya, Edwards, Megan R, Basler, Christopher F

“…Měnglà virus (MLAV), identified in bats, is a phylogenetically distinct member of the family Because the filoviruses Ebola virus (EBOV) and Marburg virus…”
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The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo by Rhodin, Michael H. J., Reyes, Archie C., Balakrishnan, Anand, Bisht, Nalini, Kelly, Nicole M., Gibbons, Joyce Sweeney, Lloyd, Jonathan, Vaine, Michael, Cressey, Tessa, Crepeau, Miranda, Shen, Ruichao, Manalo, Nathan, Castillo, Jonathan, Levene, Rachel E., Leonard, Daniel, Zang, Tianzhu, Jiang, Lijuan, Daniels, Kellye, Cox, Robert M., Lieber, Carolin M., Wolf, Josef D., Plemper, Richard K., Leist, Sarah R., Scobey, Trevor, Baric, Ralph S., Wang, Guoqiang, Goodwin, Bryan, Or, Yat Sun

“…The COVID-19 pandemic has led to the deaths of millions of people and severe global economic impacts. Small molecule therapeutics have played an important role…”
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Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain by Wu, Chao, Qavi, Abraham J., Hachim, Asmaa, Kavian, Niloufar, Cole, Aidan R., Moyle, Austin B., Wagner, Nicole D., Sweeney-Gibbons, Joyce, Rohrs, Henry W., Gross, Michael L., Peiris, J. S. Malik, Basler, Christopher F., Farnsworth, Christopher W., Valkenburg, Sophie A., Amarasinghe, Gaya K., Leung, Daisy W.

“…Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays key roles in the replication cycle and is a critical serological…”
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Domain-specific biochemical and serological characterization of SARS-CoV-2 nucleocapsid protein by Wu, Chao, Qavi, Abraham J., Moyle, Austin B., Wagner, Nicole D., Hachim, Asmaa, Kavian, Niloufar, Cole, Aidan R., Sweeney-Gibbons, Joyce, Rohrs, Henry W., Peiris, J.S. Malik, Basler, Christopher F., Gross, Michael L., Valkenburg, Sophie A., Farnsworth, Christopher W., Amarasinghe, Gaya K., Leung, Daisy W.

“…Nucleocapsid proteins are essential for SARS-CoV-2 life cycle. Here, we describe protocols to gather domain-specific insights about essential properties of…”
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Marburg and Ebola Virus mRNA 3' Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing by Khadka, Sudip, Williams, Caroline G, Sweeney-Gibbons, Joyce, Basler, Christopher F

“…The filovirus family includes deadly pathogens such as Ebola virus (EBOV) and Marburg virus (MARV). A substantial portion of filovirus genomes encode 5' and 3'…”
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Mechanisms of anti-vesicular stomatitis virus activity of deazaneplanocin and its 3-brominated analogs by Gibbons, Joyce Sweeney, Khadka, Sudip, Williams, Caroline G., Wang, Lin, Schneller, Stewart W., Liu, Chong, Tufariello, JoAnn M., Basler, Christopher F.

“…3-deazaneplanocin A (DzNep) and its 3-brominated analogs inhibit replication of several RNA viruses. This antiviral activity is attributed to inhibition of…”
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