Search Results - "Gibbins, J."

Quantitative longitudinal T2 mapping for assessing placental function and association with adverse pregnancy outcomes across gestation by Schabel, Matthias C, Roberts, Victoria H J, Gibbins, Karen J, Rincon, Monica, Gaffney, Jessica E, Streblow, Aaron D, Wright, Adam M, Lo, Jamie O, Park, Byung, Kroenke, Christopher D, Szczotka, Kathryn, Blue, Nathan R, Page, Jessica M, Harvey, Kathy, Varner, Michael W, Silver, Robert M, Frias, Antonio E

“…Existing methods for evaluating in vivo placental function fail to reliably detect pregnancies at-risk for adverse outcomes prior to maternal and/or fetal…”
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Platelet signaling: a complex interplay between inhibitory and activatory networks by Bye, A. P., Unsworth, A. J., Gibbins, J. M.

“…Summary The role of platelets in hemostasis and thrombosis is dependent on a complex balance of activatory and inhibitory signaling pathways. Inhibitory…”
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Maternal and fetal morbidity associated with uterine rupture of the unscarred uterus by Gibbins, Karen J., MD, Weber, Tiffany, MD, Holmgren, Calla M., MD, Porter, T. Flint, MD, Varner, Michael W., MD, Manuck, Tracy A., MD

“…Objective We sought to report obstetric and neonatal characteristics and outcomes following primary uterine rupture in a large contemporary obstetric cohort…”
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Mode of induction of platelet-derived extracellular vesicles is a critical determinant of their phenotype and function by Ferreira, P. M., Bozbas, E., Tannetta, S. D., Alroqaiba, N., Zhou, R., Crawley, J. T. B., Gibbins, J. M., Jones, C. I., Ahnström, J., Yaqoob, P.

“…Platelet-derived extracellular vesicles (PDEVs) are the most abundant amongst all types of EVs in the circulation. However, the mechanisms leading to PDEVs…”
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Zinc regulates reactive oxygen species generation in platelets by Lopes-Pires, M.E., Ahmed, N. S., Vara, D., Gibbins, J. M., Pula, G., Pugh, N.

“…Vascular complications resulting from atherosclerosis development are a major cause of death. Reactive oxygen species (ROS) are produced by platelets during…”
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Move along, nothing to see here: Btk inhibitors stop platelets sticking to plaques by Bye, A. P., Gibbins, J. M.

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Antiphospholipid antibodies in women with severe preeclampsia and placental insufficiency: a case-control study by Gibbins, K J, Tebo, A E, Nielsen, S K, Branch, D W

“…Objective Preterm delivery for preeclampsia or placental insufficiency (PREPI) is a clinical criterion for antiphospholipid syndrome (APS), but no prior…”
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Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones by Belyaev, A.V., Dunster, J.L., Gibbins, J.M., Panteleev, M.A., Volpert, V.

“…Hemostasis is a complex physiological mechanism that functions to maintain vascular integrity under any conditions. Its primary components are blood platelets…”
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Future innovations in anti‐platelet therapies by Barrett, N E, Holbrook, L, Jones, S, Kaiser, W J, Moraes, L A, Rana, R, Sage, T, Stanley, R G, Tucker, K L, Wright, B, Gibbins, J M

“…Platelets have long been recognized to be of central importance in haemostasis, but their participation in pathological conditions such as thrombosis,…”
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Unique Genetic and Histological Signatures of Mouse Pericardial Adipose Tissue by Al-Dibouni, A, Gaspar, R, Ige, S, Boateng, S, Cagampang, F R, Gibbins, J, Cox, R D, Sellayah, D

“…Obesity is a major risk factor for a plethora of metabolic disturbances including diabetes and cardiovascular disease. Accumulating evidence is showing that…”
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Stillbirth and fetal anomalies: secondary analysis of a case–control study by Son, SL, Allshouse, AA, Page, JM, Debbink, MP, Pinar, H, Reddy, U, Gibbins, KJ, Stoll, BJ, Parker, CB, Dudley, DJ, Varner, MW, Silver, RM, Conway, Deborah, Aufdemorte, Karen, Rodriguez, Angela, Pina, Monica, Nelson, Kristi, Rowland Hogue, Carol J, Tinsley, Janice Daniels, Shehata, Bahig, Abramowsky, Carlos, Coustan, Donald, Carpenter, Marshall, Kubaska, Susan, Saade, George R, Bukowski, Radek, Rollins, Jennifer Lee, Hawkins, Hal, Sbrana, Elena, Koch, Matthew A, Thorsten, Vanessa R, Franklin, Holly, Chen, Pinliang, Shriver, Eunice Kennedy, Willinger, Marian, Goldenberg, Robert L

“…Objective Approximately 10% of stillbirths are attributed to fetal anomalies, but anomalies are also common in live births. We aimed to assess the relationship…”
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Factors affecting coal particle ignition under oxyfuel combustion atmospheres by Man, C.K., Gibbins, J.R.

“…A set of 13 coals of different rank has been tested for ignition propensity in a 20-L explosion chamber simulating oxyfuel combustion gas conditions. Their…”
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The platelet‐surface thiol isomerase enzyme ERp57 modulates platelet function by HOLBROOK, L.‐M., SASIKUMAR, P., STANLEY, R. G., SIMMONDS, A. D., BICKNELL, A. B., GIBBINS, J. M.

“…Background: Thiol isomerases are a family of endoplasmic reticulum enzymes which orchestrate redox‐based modifications of protein disulphide bonds. Previous…”
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A humanized monoclonal antibody that inhibits platelet‐surface ERp72 reveals a role for ERp72 in thrombosis by Holbrook, L.‐M., Sandhar, G. K., Sasikumar, P., Schenk, M. P., Stainer, A. R., Sahli, K. A., Flora, G. D., Bicknell, A. B., Gibbins, J. M.

“…Essentials ERp72 is a thiol isomerase enzyme. ERp72 levels increase at the platelet surface during platelet activation. We generated a humanized monoclonal…”
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An analysis of the microstructure and properties of cold-rolled Ni:Al laminate foils by Stover, A. K., Krywopusk, N. M., Fritz, G. M., Barron, S. C., Gibbins, J. D., Weihs, T. P.

“…Ni:Al laminate composites were fabricated by repeatedly cold-rolling Al and Ni foils that were stacked together with initial thicknesses of 25 and 18 μm,…”
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The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis by Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P., Sage, T., Ushioda, R., Nagata, K., Farndale, R. W., Gibbins, J. M.

“…Essentials Heat shock protein 47 (HSP47), a collagen specific chaperone is present on the platelet surface. Collagen mediated platelet function was reduced…”
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PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity by Unsworth, A. J., Kriek, N., Bye, A. P., Naran, K., Sage, T., Flora, G. D., Gibbins, J. M.

“…Essentials peroxisome proliferator‐activated receptor γ (PPARγ) agonists inhibit platelet function. PPARγ agonists negatively regulate outside‐in signaling via…”
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Ingestion of quercetin inhibits platelet aggregation and essential components of the collagen‐stimulated platelet activation pathway in humans by Hubbard, G. P., Wolffram, S., Lovegrove, J. A., Gibbins, J. M.

“…Background: Quercetin, a flavonoid present in the human diet, which is found in high levels in onions, apples, tea and wine, has been shown previously to…”
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Reproductive Rights Advocacy: Not Just for the Family Planning Community by Heuser, Cara C., MD MS, Gibbins, Karen J., MD, Smid, Marcela C., MD MS MA, Branch, D. Ware, MD

“…Abstract Women and families benefit from access to the full spectrum of reproductive care, including family planning services. We commend our family planning…”
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Mechanical fabrication of reactive metal laminate powders by Stover, A. K., Krywopusk, N. M., Gibbins, J. D., Weihs, T. P.

“…A new mechanical method for creating reactive laminate powders has been developed using a two-step process; in the first step bulk reactive materials are…”
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