Search Results - "Gibault, Laure"

Induction of resident memory T cells enhances the efficacy of cancer vaccine by Nizard, Mevyn, Roussel, Hélène, Diniz, Mariana O., Karaki, Soumaya, Tran, Thi, Voron, Thibault, Dransart, Estelle, Sandoval, Federico, Riquet, Marc, Rance, Bastien, Marcheteau, Elie, Fabre, Elizabeth, Mandavit, Marion, Terme, Magali, Blanc, Charlotte, Escudie, Jean-Baptiste, Gibault, Laure, Barthes, Françoise Le Pimpec, Granier, Clemence, Ferreira, Luis C. S., Badoual, Cecile, Johannes, Ludger, Tartour, Eric

“…Tissue-resident memory T cells (Trm) represent a new subset of long-lived memory T cells that remain in tissue and do not recirculate. Although they are…”
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Base-Position Error Rate Analysis of Next-Generation Sequencing Applied to Circulating Tumor DNA in Non-Small Cell Lung Cancer: A Prospective Study by Pécuchet, Nicolas, Zonta, Eleonora, Didelot, Audrey, Combe, Pierre, Thibault, Constance, Gibault, Laure, Lours, Camille, Rozenholc, Yves, Taly, Valérie, Laurent-Puig, Pierre, Blons, Hélène, Fabre, Elizabeth

“…Circulating tumor DNA (ctDNA) is an approved noninvasive biomarker to test for the presence of EGFR mutations at diagnosis or recurrence of lung cancer…”
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Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin by REMARK, Romain, ALIFANO, Marco, FLEJOU, Jean-François, GIBAULT, Laure, VERKARRE, Virginie, REGNARD, Jean-François, PAGES, Olivier-Nicolas, OUDARD, Stéphane, MLECNIK, Bernhard, SAUTES-FRIDMAN, Catherine, FRIDMAN, Wolf-Herman, DAMOTTE, Diane, CREMER, Isabelle, LUPO, Audrey, DIEU-NOSJEAN, Marie-Caroline, RIQUET, Marc, CROZET, Lucile, OUAKRIM, Hanane, GOC, Jeremy, CAZES, Aurélie

“…If immune cells are involved in tumor surveillance and have a prognostic impact in most primary tumors, little is known about their significance in metastases…”
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Clinical and molecular characteristics associated with high PD-L1 expression in EGFR-mutated lung adenocarcinoma by Slomka, Jeremy, Berthou, Hugo, Mansuet-Lupo, Audrey, Blons, Hélène, Fabre, Elizabeth, Lerner, Ivan, Rance, Bastien, Alifano, Marco, Chapron, Jeanne, Birsen, Gary, Gibault, Laure, Arrondeau, Jennifer, Leroy, Karen, Wislez, Marie

“…Objective Recent evidence suggests that elevated levels of PD-L1 expression may be linked to early resistance to TKI and reduced survival in NSCLC with EGFR…”
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Clinical assessment of the miR-34, miR-200, ZEB1 and SNAIL EMT regulation hub underlines the differential prognostic value of EMT miRs to drive mesenchymal transition and prognosis in resected NSCLC by Garinet, Simon, Didelot, Audrey, Denize, Thomas, Perrier, Alexandre, Beinse, Guillaume, Leclere, Jean-Baptiste, Oudart, Jean-Baptiste, Gibault, Laure, Badoual, Cecile, Le Pimpec-Barthes, Françoise, Laurent-Puig, Pierre, Legras, Antoine, Blons, Helene

“…Background Patients with non-small cell lung cancer (NSCLC) receiving curative surgery have a risk of relapse, and adjuvant treatments only translate into a 5%…”
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Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival by Quetel, Lisa, Meiller, Clément, Assié, Jean‐Baptiste, Blum, Yuna, Imbeaud, Sandrine, Montagne, François, Tranchant, Robin, Wolf, Julien, Caruso, Stefano, Copin, Marie‐Christine, Hofman, Véronique, Gibault, Laure, Badoual, Cécile, Pintilie, Ecaterina, Hofman, Paul, Monnet, Isabelle, Scherpereel, Arnaud, Le Pimpec‐Barthes, Françoise, Zucman‐Rossi, Jessica, Jaurand, Marie‐Claude, Jean, Didier

“…Development of precision medicine for malignant pleural mesothelioma (MPM) requires a deep knowledge of tumor heterogeneity. Histologic and molecular…”
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Vascular Ehlers–Danlos syndrome (vEDS): CT and histologic findings of pleural and lung parenchymal damage by Boussouar, Samia, Benattia, Amira, Escudié, Jean.-Baptiste, Gibault, Laure, Capron, Frédérique, Legrand, Anne, Brillet, Pierre-Yves, Jeunemaitre, Xavier, Grenier, Philippe A., Mousseaux, Elie, Frank, Michael, Sanchez, Olivier

“…Objectives To describe CT features of lung involvement in patients with vascular Ehlers–Danlos syndrome (vEDS), a rare genetic condition caused by pathogenic…”
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Epithelial-to-Mesenchymal Transition and MicroRNAs in Lung Cancer by Legras, Antoine, Pécuchet, Nicolas, Imbeaud, Sandrine, Pallier, Karine, Didelot, Audrey, Roussel, Hélène, Gibault, Laure, Fabre, Elizabeth, Le Pimpec-Barthes, Françoise, Laurent-Puig, Pierre, Blons, Hélène

“…Despite major advances, non-small cell lung cancer (NSCLC) remains the major cause of cancer-related death in developed countries. Metastasis and drug…”
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Transbronchial cryobiopsy proven amyloid diffuse cystic lung disease complicating a transthyretin mutated (ATTRm) amyloidosis: a case report by Gaultier, Sébastien, Puscas, Tania, Pastre, Jean, Gibault, Laure, Arlet, Jean-Benoît, Cauquil, Cécile, Michon, Adrien

“…We present a case report of transbronchial cryobiopsy proven diffuse amyloid cystic lung disease complicating a homozygous Val122Ile (V122I) transthyretin…”
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High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition by Tavernier, Quentin, Legras, Antoine, Didelot, Audrey, Normand, Corinne, Gibault, Laure, Badoual, Cécile, Le Pimpec-Barthes, Françoise, Puig, Pierre Laurent, Blons, Hélène, Pallet, Nicolas

“…Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor growth and aggressiveness. Endoplasmic Reticulum (ER) stress has been…”
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Morphologic and molecular study of lung cancers associated with idiopathic pulmonary fibrosis and other pulmonary fibroses by Guyard, Alice, Danel, Claire, Théou-Anton, Nathalie, Debray, Marie-Pierre, Gibault, Laure, Mordant, Pierre, Castier, Yves, Crestani, Bruno, Zalcman, Gérard, Blons, Hélène, Cazes, Aurélie

“…Primitive lung cancers developed on lung fibroses are both diagnostic and therapeutic challenges. Their incidence may increase with new more efficient lung…”
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A novel Chr1-miR-200 driven whole transcriptome signature shapes tumor immune microenvironment and predicts relapse in early-stage lung adenocarcinoma by Garinet, Simon, Didelot, Audrey, Marisa, Laetitia, Beinse, Guillaume, Sroussi, Marine, Le Pimpec-Barthes, Françoise, Fabre, Elizabeth, Gibault, Laure, Laurent-Puig, Pierre, Mouillet-Richard, Sophie, Legras, Antoine, Blons, Hélène

“…In Lung adenocarcinoma (LUAD), targeted therapies and immunotherapies have moved from metastatic to early stage and stratification of the relapse risk becomes…”
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CXCR6 deficiency impairs cancer vaccine efficacy and CD8+ resident memory T-cell recruitment in head and neck and lung tumors by Karaki, Soumaya, Blanc, Charlotte, Tran, Thi, Galy-Fauroux, Isabelle, Mougel, Alice, Dransart, Estelle, Anson, Marie, Tanchot, Corinne, Paolini, Lea, Gruel, Nadege, Gibault, Laure, Lepimpec-Barhes, Francoise, Fabre, Elizabeth, Benhamouda, Nadine, Badoual, Cecile, Damotte, Diane, Donnadieu, Emmanuel, Kobold, Sebastian, Mami-Chouaib, Fathia, Golub, Rachel, Johannes, Ludger, Tartour, Eric

“…BackgroundResident memory T lymphocytes (TRM) are located in tissues and play an important role in immunosurveillance against tumors. The presence of TRM prior…”
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Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma by Meiller, Clément, Montagne, François, Hirsch, Theo Z, Caruso, Stefano, de Wolf, Julien, Bayard, Quentin, Assié, Jean-Baptiste, Meunier, Léa, Blum, Yuna, Quetel, Lisa, Gibault, Laure, Pintilie, Ecaterina, Badoual, Cécile, Humez, Sarah, Galateau-Sallé, Françoise, Copin, Marie-Christine, Letouzé, Eric, Scherpereel, Arnaud, Zucman-Rossi, Jessica, Le Pimpec-Barthes, Françoise, Jaurand, Marie-Claude, Jean, Didier

“…Malignant pleural mesothelioma (MPM) is a heterogeneous cancer. Better knowledge of molecular and cellular intra-tumor heterogeneity throughout the thoracic…”
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Number of Mediastinal Lymph Nodes in Non-Small Cell Lung Cancer: A Gaussian Curve, Not a Prognostic Factor by Riquet, Marc, MD, PhD, Legras, Antoine, MD, Mordant, Pierre, MD, PhD, Rivera, Caroline, MD, Arame, Alex, MD, Gibault, Laure, MD, Foucault, Christophe, MD, Dujon, Antoine, MD, Le Pimpec Barthes, Françoise, MD, PhD

“…Background It has been proposed that examining a greater number of lymph nodes (LNs) in patients with non–small-cell lung cancer (NSCLC) treated by surgical…”
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Best imaging signs identified by radiomics could outperform the model: application to differentiating lung carcinoid tumors from atypical hamartomas by Habert, Paul, Decoux, Antoine, Chermati, Lilia, Gibault, Laure, Thomas, Pascal, Varoquaux, Arthur, Le Pimpec-Barthes, Françoise, Arnoux, Armelle, Juquel, Loïc, Chaumoitre, Kathia, Garcia, Stéphane, Gaubert, Jean-Yves, Duron, Loïc, Fournier, Laure

“…Objectives Lung carcinoids and atypical hamartomas may be difficult to differentiate but require different treatment. The aim was to differentiate these tumors…”
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Early T cell signalling is reversibly altered in PD-1+ T lymphocytes infiltrating human tumors by Wang, Shu-Fang, Fouquet, Stéphane, Chapon, Maxime, Salmon, Hélène, Regnier, Fabienne, Labroquère, Karine, Badoual, Cécile, Damotte, Diane, Validire, Pierre, Maubec, Eve, Delongchamps, Nicolas B, Cazes, Aurélie, Gibault, Laure, Garcette, Marylène, Dieu-Nosjean, Marie-Caroline, Zerbib, Marc, Avril, Marie-Françoise, Prévost-Blondel, Armelle, Randriamampita, Clotilde, Trautmann, Alain, Bercovici, Nadège

“…To improve cancer immunotherapy, a better understanding of the weak efficiency of tumor-infiltrating T lymphocytes (TIL) is necessary. We have analyzed the…”
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Development and validation of a rabbit model of Pseudomonas aeruginosa non-ventilated pneumonia for preclinical drug development by Gras, Emmanuelle, Vu, Trang T T, Nguyen, Nhu T Q, Tran, Vuvi G, Mao, Yanjie, Tran, Nguyen D, Mai, Nam H, Dong, Oliver X, Jung, David H, Iorio, Natalia L P P, Povoa, Helvecio C C, Pinheiro, Marcos Gabriel, Aguiar-Alves, Fabio, Weiss, William J, Zheng, Bo, Cheng, Lily I, Stover, Charles K, Sellman, Bret R, DiGiandomenico, Antonio, Gibault, Laure, Valour, Florent, Diep, Binh An

“…New drugs targeting antimicrobial resistant pathogens, including , have been challenging to evaluate in clinical trials, particularly for the non-ventilated…”
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Composite biomarkers defined by multiparametric immunofluorescence analysis identify ALK-positive adenocarcinoma as a potential target for immunotherapy by Roussel, Hélène, De Guillebon, Eléonore, Biard, Lucie, Mandavit, Marion, Gibault, Laure, Fabre, Elisabeth, Antoine, Martine, Hofman, Paul, Beau-Faller, Michèle, Blons, Hélène, Danel, Claire, Barthes, Françoise Le Pimpec, Gey, Alain, Granier, Clémence, Wislez, Marie, Laurent-Puig, Pierre, Oudard, Stéphane, Bruneval, Patrick, Badoual, Cécile, Cadranel, Jacques, Tartour, Eric

“…Anaplastic lymphoma kinase (ALK) inhibitors have been successfully developed for non-small cell lung carcinoma (NSCLC) displaying chromosomal rearrangements of…”
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Strong Smooth Muscle Differentiation Is Dependent on Myocardin Gene Amplification in Most Human Retroperitoneal Leiomyosarcomas by PEROT, Gaëlle, DERRE, Josette, COINDRE, Jean-Michel, TIRODE, Franck, LUCCHESI, Carlo, MARIANI, Odette, GIBAULT, Laure, GUIHOU, Louis, TERRIER, Philippe, AURIAS, Alain

“…Myocardin (MYOCD), a serum response factor (SRF) transcriptional cofactor, is essential for cardiac and smooth muscle development and differentiation. We show…”
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