Search Results - "Giavalisco, P"

Small-molecule inhibitors of human mitochondrial DNA transcription by Bonekamp, Nina A., Peter, Bradley, Hillen, Hauke S., Felser, Andrea, Bergbrede, Tim, Choidas, Axel, Horn, Moritz, Unger, Anke, Di Lucrezia, Raffaella, Atanassov, Ilian, Li, Xinping, Koch, Uwe, Menninger, Sascha, Boros, Joanna, Habenberger, Peter, Giavalisco, Patrick, Cramer, Patrick, Denzel, Martin S., Nussbaumer, Peter, Klebl, Bert, Falkenberg, Maria, Gustafsson, Claes M., Larsson, Nils-Göran

“…Altered expression of mitochondrial DNA (mtDNA) occurs in ageing and a range of human pathologies (for example, inborn errors of metabolism, neurodegeneration…”
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Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction by Motori, E, Atanassov, I, Kochan, S M V, Folz-Donahue, K, Sakthivelu, V, Giavalisco, P, Toni, N, Puyal, J, Larsson, N-G

“…Neurodegeneration in mitochondrial disorders is considered irreversible because of limited metabolic plasticity in neurons, yet the cell-autonomous…”
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Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR‐Cas9 screen by Mennuni, Mara, Filograna, Roberta, Felser, Andrea, Bonekamp, Nina A, Giavalisco, Patrick, Lytovchenko, Oleksandr, Larsson, Nils‐Göran

“…Cancer cells depend on mitochondria to sustain their increased metabolic need and mitochondria therefore constitute possible targets for cancer treatment. We…”
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Towards the proteome of Brassica napus phloem sap by Giavalisco, Patrick, Kapitza, Kristin, Kolasa, Anna, Buhtz, Anja, Kehr, Julia

“…The soluble proteins in sieve tube exudate from Brassica napus plants were systematically analyzed by 1‐DE and high‐resolution 2‐DE, partial amino acid…”
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Cellular pyrimidine imbalance triggers mitochondrial DNA–dependent innate immunity by Sprenger, Hans-Georg, MacVicar, Thomas, Bahat, Amir, Fiedler, Kai Uwe, Hermans, Steffen, Ehrentraut, Denise, Ried, Katharina, Milenkovic, Dusanka, Bonekamp, Nina, Larsson, Nils-Göran, Nolte, Hendrik, Giavalisco, Patrick, Langer, Thomas

“…Cytosolic mitochondrial DNA (mtDNA) elicits a type I interferon response, but signals triggering the release of mtDNA from mitochondria remain enigmatic. Here,…”
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SlCCD7 controls strigolactone biosynthesis, shoot branching and mycorrhiza-induced apocarotenoid formation in tomato by Vogel, Jonathan T, Walter, Michael H, Giavalisco, Patrick, Lytovchenko, Anna, Kohlen, Wouter, Charnikhova, Tatsiana, Simkin, Andrew J, Goulet, Charles, Strack, Dieter, Bouwmeester, Harro J, Fernie, Alisdair R, Klee, Harry J

“…The regulation of shoot branching is an essential determinant of plant architecture, integrating multiple external and internal signals. One of the signaling…”
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Proteomics of curcurbit phloem exudate reveals a network of defence proteins by Walz, Christina, Giavalisco, Patrick, Schad, Martina, Juenger, Melanie, Klose, Joachim, Kehr, Julia

“…Analysis of cucumber and pumpkin phloem sap proteins by one- and two-dimensional gel electrophoresis identified a range of proteins involved in plant defence…”
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Intra- and Interspecific Variation in Primate Gene Expression Patterns by Enard, Wolfgang, Khaitovich, Philipp, Klose, Joachim, Zöllner, Sebastian, Heissig, Florian, Giavalisco, Patrick, Nieselt-Struwe, Kay, Muchmore, Elaine, Varki, Ajit, Ravid, Rivka, Doxiadis, Gaby M., Bontrop, Ronald E., Pääbo, Svante

“…Although humans and their closest evolutionary relatives, the chimpanzees, are 98.7% identical in their genomic DNA sequences, they differ in many…”
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Spatial and single-cell profiling of the metabolome, transcriptome and epigenome of the aging mouse liver by Nikopoulou, Chrysa, Kleinenkuhnen, Niklas, Parekh, Swati, Sandoval, Tonantzi, Ziegenhain, Christoph, Schneider, Farina, Giavalisco, Patrick, Donahue, Kat-Folz, Vesting, Anna Juliane, Kirchner, Marcel, Bozukova, Mihaela, Vossen, Christian, Altmüller, Janine, Wunderlich, Thomas, Sandberg, Rickard, Kondylis, Vangelis, Tresch, Achim, Tessarz, Peter

“…Tissues within an organism and even cell types within a tissue can age with different velocities. However, it is unclear whether cells of one type experience…”
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Inhibition of mammalian mtDNA transcription acts paradoxically to reverse diet-induced hepatosteatosis and obesity by Jiang, Shan, Yuan, Taolin, Rosenberger, Florian A., Mourier, Arnaud, Dragano, Nathalia R. V., Kremer, Laura S., Rubalcava-Gracia, Diana, Hansen, Fynn M., Borg, Melissa, Mennuni, Mara, Filograna, Roberta, Alsina, David, Misic, Jelena, Koolmeister, Camilla, Papadea, Polyxeni, de Angelis, Martin Hrabe, Ren, Lipeng, Andersson, Olov, Unger, Anke, Bergbrede, Tim, Di Lucrezia, Raffaella, Wibom, Rolf, Zierath, Juleen R., Krook, Anna, Giavalisco, Patrick, Mann, Matthias, Larsson, Nils-Göran

“…The oxidative phosphorylation system 1 in mammalian mitochondria plays a key role in transducing energy from ingested nutrients 2 . Mitochondrial metabolism is…”
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Proteome analysis of Arabidopsis thaliana by two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionisation-time of flight mass spectrometry by Giavalisco, Patrick, Nordhoff, Eckhard, Kreitler, Thomas, Klöppel, Klaus-Dieter, Lehrach, Hans, Klose, Joachim, Gobom, Johan

“…In the present study we show results of a large‐scale proteome analysis of the recently sequenced plant Arabidopsis thaliana. On the basis of a previously…”
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Extraction of proteins from plant tissues for two-dimensional electrophoresis analysis by Giavalisco, Patrick, Nordhoff, Eckhard, Lehrach, Hans, Gobom, Johan, Klose, Joachim

“…To increase the number of proteins detectable by two‐dimensional electrophoresis (2‐DE) in plants, we present a new procedure for extracting total proteins…”
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High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome by Giavalisco, P, Wilson, D, Kreitler, T, Lehrach, H, Klose, J, Gobom, J, Fucini, P

“…Proteomic studies have addressed the composition of plant chloroplast ribosomes and 70S ribosomes from the unicellular organism Chlamydomonas reinhardtii But…”
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Evaluation of two-dimensional electrophoresis and liquid chromatography - tandem mass spectrometry for tissue-specific protein profiling of laser-microdissected plant samples by Schad, Martina, Lipton, Mary S., Giavalisco, Patrick, Smith, Richard D., Kehr, Julia

“…Laser microdissection (LM) allows the collection of homogeneous tissue‐ and cell‐specific plant samples. The employment of this technique with subsequent…”
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Large-scale plant proteomics by Kersten, Birgit, Bürkle, Lukas, Kuhn, Eckehard J, Giavalisco, Patrick, Konthur, Zoltan, Lueking, Angelika, Walter, Gerald, Eickhoff, Holger, Schneider, Ulrich

“…Large-scale and high throughput approaches increasingly play an essential role in the study of biological systems, which are per se highly complex. Therefore,…”
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Protein Identification by MALDI-TOF-MS Peptide Mapping:  A New Strategy by Egelhofer, Volker, Gobom, Johan, Seitz, Harald, Giavalisco, Patrick, Lehrach, Hans, Nordhoff, Eckhard

“…A new strategy for identifying proteins by MALDI-TOF-MS peptide mapping is reported. In contrast to current approaches, the strategy does not rely on a good…”
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Transformation and other factors of the peptide mass spectrometry pairwise peak-list comparison process by Wolski, Witold E, Lalowski, Maciej, Martus, Peter, Herwig, Ralf, Giavalisco, Patrick, Gobom, Johan, Sickmann, Albert, Lehrach, Hans, Reinert, Knut

“…Biological Mass Spectrometry is used to analyse peptides and proteins. A mass spectrum generates a list of measured mass to charge ratios and intensities of…”
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Evaluation of two-dimensional electrophoresis and liquid chromatography - tandem mass spectrometry for tissue-specific protein profiling of laser-microdissected plant samples by Schad, Martina, Lipton, Mary S., Giavalisco, Patrick, Smith, Richard D., Kehr, Julia

“…See original http://dx.doi.org/10.1002/elps.200410399…”
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Large-gel two-dimensional electrophoresis-matrix assisted laser desorption/ionization-time of flight-mass spectrometry: An analytical challenge for studying complex protein mixtures by Nordhoff, Eckhard, Egelhofer, Volker, Giavalisco, Patrick, Eickhoff, Holger, Horn, Martin, Przewieslik, Thomas, Theiss, Dorothea, Schneider, Ulrich, Lehrach, Hans, Gobom, Johan

“…The large‐gel two‐dimensional electrophoresis (2‐DE) technique, developed by Klose and co‐workers over the past 25 years, provides the resolving power…”
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