Search Results - "Gias, Carlos"

A role for the ciliary marginal zone in the melanopsin-dependent intrinsic pupillary light reflex by Semo, Ma'ayan, Gias, Carlos, Ahmado, Ahmad, Vugler, Anthony

“…Maintenance of pupillary constriction in light-adapted rodents has traditionally been thought to involve a reflex between retina, brain and iris, with recent…”
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Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat by Carr, Amanda-Jayne, Vugler, Anthony A, Hikita, Sherry T, Lawrence, Jean M, Gias, Carlos, Chen, Li Li, Buchholz, David E, Ahmado, Ahmad, Semo, Ma'ayan, Smart, Matthew J K, Hasan, Shazeen, da Cruz, Lyndon, Johnson, Lincoln V, Clegg, Dennis O, Coffey, Pete J

“…Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs)…”
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Melanopsin contributions to irradiance coding in the thalamo-cortical visual system by Brown, Timothy M, Gias, Carlos, Hatori, Megumi, Keding, Sheena R, Semo, Ma'ayan, Coffey, Peter J, Gigg, John, Piggins, Hugh D, Panda, Satchidananda, Lucas, Robert J

“…Photoreception in the mammalian retina is not restricted to rods and cones but extends to a subset of retinal ganglion cells expressing the photopigment…”
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Elucidating the phenomenon of HESC-derived RPE: Anatomy of cell genesis, expansion and retinal transplantation by Vugler, Anthony, Carr, Amanda-Jayne, Lawrence, Jean, Chen, Li Li, Burrell, Kelly, Wright, Andrew, Lundh, Peter, Semo, Ma'ayan, Ahmado, Ahmad, Gias, Carlos, da Cruz, Lyndon, Moore, Harry, Andrews, Peter, Walsh, James, Coffey, Peter

“…Healthy Retinal Pigment Epithelium (RPE) cells are required for proper visual function and the phenomenon of RPE derivation from Human Embryonic Stem Cells…”
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Hsp90 inhibition protects against inherited retinal degeneration by Aguilà, Mònica, Bevilacqua, Dalila, McCulley, Caroline, Schwarz, Nele, Athanasiou, Dimitra, Kanuga, Naheed, Novoselov, Sergey S, Lange, Clemens A K, Ali, Robin R, Bainbridge, James W, Gias, Carlos, Coffey, Peter J, Garriga, Pere, Cheetham, Michael E

“…The molecular chaperone Hsp90 is important for the functional maturation of many client proteins, and inhibitors are in clinical trials for multiple…”
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Induction of differentiation by pyruvate and DMEM in the human retinal pigment epithelium cell line ARPE-19 by Ahmado, Ahmad, Carr, Amanda-Jayne, Vugler, Anthony A, Semo, Ma'ayan, Gias, Carlos, Lawrence, Jean M, Chen, Li Li, Chen, Fred K, Turowski, Patric, da Cruz, Lyndon, Coffey, Peter J

“…Cultured retinal pigment epithelium (RPE) may become a therapeutic option for transplantation in retinal disease. However maintaining a native RPE phenotype in…”
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Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction by Coffey, Peter J, Gias, Carlos, McDermott, Caroline J, Lundh, Peter, Pickering, Matthew C, Sethi, Charanjit, Bird, Alan, Fitzke, Fred W, Maass, Annelie, Chen, Li Li, Holder, Graham E, Luthert, Philip J, Salt, Thomas E, Moss, Stephen E, Greenwood, John

“…Age-related macular degeneration is the most common form of legal blindness in westernized societies, and polymorphisms in the gene encoding complement factor…”
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Dissecting a role for melanopsin in behavioural light aversion reveals a response independent of conventional photoreception by Semo, Ma'ayan, Gias, Carlos, Ahmado, Ahmad, Sugano, Eriko, Allen, Annette E, Lawrence, Jean M, Tomita, Hiroshi, Coffey, Peter J, Vugler, Anthony A

“…Melanopsin photoreception plays a vital role in irradiance detection for non-image forming responses to light. However, little is known about the involvement…”
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The effect of hypercapnia on the neural and hemodynamic responses to somatosensory stimulation by Jones, Myles, Berwick, Jason, Hewson-Stoate, Nicola, Gias, Carlos, Mayhew, John

“…Modern non-invasive imaging techniques utilize the coupling between neural activity and changes in blood flow, volume and oxygenation to map the functional…”
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Adaptive Optics Imaging Shows Rescue of Macula Cone Photoreceptors by Muthiah, Manickam Nick, MRCOphth, MEd, Keane, Pearse A., MD, FRCOphth, Zhong, Joe, PhD, Gias, Carlos, PhD, Uppal, Gurmit, MD, FRCOphth, Coffey, Peter J., PhD, da Cruz, Lyndon, FRCOphth, PhD

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Degeneration of cortical function in the Royal College of Surgeons rat by Gias, Carlos, Vugler, Anthony, Lawrence, Jean, Carr, Amanda Jayne, Chen, Li Li, Ahmado, Ahmed, Semo, Ma’ayan, Coffey, Peter J.

“…► Royal College of Surgeons rat brain electrophysiology. ► Early degeneration in the cortical processing to gratings stimulation. ► Cortical processing to…”
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Preservation of visual cortical function following retinal pigment epithelium transplantation in the RCS rat using optical imaging techniques by Gias, Carlos, Jones, Myles, Keegan, David, Adamson, Peter, Greenwood, John, Lund, Ray, Martindale, John, Johnston, David, Berwick, Jason, Mayhew, John, Coffey, Peter

“…The aim of this study was to determine the extent of cortical functional preservation following retinal pigment epithelium (RPE) transplantation in the Royal…”
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Retrograde Melanopsin Signaling Increases With Age in Retinal Degenerate Mice Lacking Rods and the Majority of Cones by Semo, Ma'ayan, Coffey, Peter, Gias, Carlos, Vugler, Anthony

“…Following on from reports of retrograde retinal signaling in mice, we sought to investigate the influence of age and retinal location on this phenomenon using…”
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Cone photoreceptor definition on adaptive optics retinal imaging by Muthiah, Manickam Nick, Gias, Carlos, Chen, Fred Kuanfu, Zhong, Joe, McClelland, Zoe, Sallo, Ferenc B, Peto, Tunde, Coffey, Peter J, da Cruz, Lyndon

“…To quantitatively analyse cone photoreceptor matrices on images captured on an adaptive optics (AO) camera and assess their correlation to well-established…”
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Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay by Carr, Amanda-Jayne, Vugler, Anthony, Lawrence, Jean, Chen, Li Li, Ahmado, Ahmed, Chen, Fred K, Semo, Ma'ayan, Gias, Carlos, da Cruz, Lyndon, Moore, Harry D, Walsh, James, Coffey, Peter J

“…To examine the ability of retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (HESC) to phagocytose photoreceptor outer segments,…”
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Melanopsin Contributions to Irradiance Coding in the Thalamo-Cortical Visual System: e1000558 by Brown, Timothy M, Gias, Carlos, Hatori, Megumi, Keding, Sheena R, Semo, ayan, Coffey, Peter J, Gigg, John, Piggins, Hugh D, Panda, Satchidananda, Lucas, Robert J

“…Photoreception in the mammalian retina is not restricted to rods and cones but extends to a subset of retinal ganglion cells expressing the photopigment…”
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Embryonic stem cells and retinal repair by Vugler, Anthony, Lawrence, Jean, Walsh, James, Carr, Amanda, Gias, Carlos, Semo, Ma’ayan, Ahmado, Ahmad, da Cruz, Lyndon, Andrews, Peter, Coffey, Peter

“…In this review we examine the potential of embryonic stem cells (ESCs) for use in the treatment of retinal diseases involving photoreceptors and retinal…”
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