Search Results - "Giarratana, Anna"
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TGF-β signaling: critical nexus of fibrogenesis and cancer
Published in Journal of translational medicine (26-06-2024)“…The transforming growth factor-beta (TGF-β) signaling pathway is a vital regulator of cell proliferation, differentiation, apoptosis, and extracellular matrix…”
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Journal Article -
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Status of precision medicine approaches to traumatic brain injury
Published in Neural regeneration research (01-10-2022)“…Traumatic brain injury (TBI) is a serious condition in which trauma to the head causes damage to the brain, leading to a disruption in brain function. This is…”
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Journal Article -
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Adaptive coding occurs in object categorization and may not be associated with schizotypal personality traits
Published in Scientific reports (12-11-2022)“…Processing more likely inputs with higher sensitivity (adaptive coding) enables the brain to represent the large range of inputs coming in from the world…”
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Single Nucleotide Polymorphism in Cell Adhesion Molecule L1 Affects Learning and Memory in a Mouse Model of Traumatic Brain Injury
Published in International journal of molecular sciences (01-03-2024)“…The L1 cell adhesion molecule (L1) has demonstrated a range of beneficial effects in animal models of spinal cord injury, neurodegenerative disease, and…”
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APOE4 genetic polymorphism results in impaired recovery in a repeated mild traumatic brain injury model and treatment with Bryostatin-1 improves outcomes
Published in Scientific reports (16-11-2020)“…After traumatic brain injury (TBI), some people have worse recovery than others. Single nucleotide polymorphisms (SNPs) in Apolipoprotein E ( APOE ) are known…”
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BDNF Val66Met Genetic Polymorphism Results in Poor Recovery Following Repeated Mild Traumatic Brain Injury in a Mouse Model and Treatment With AAV-BDNF Improves Outcomes
Published in Frontiers in neurology (07-11-2019)“…Clinicians have long noticed that some Traumatic Brain Injury (TBI) patients have worse symptoms and take a longer time to recover than others, for reasons…”
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Advances in CAR T Cell Therapy for Non-Small Cell Lung Cancer
Published in Current issues in molecular biology (01-11-2023)“…Since its first approval by the FDA in 2017, tremendous progress has been made in chimeric antigen receptor (CAR) T cell therapy, the adoptive transfer of…”
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Journal Article -
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TGF-[beta] signaling: critical nexus of fibrogenesis and cancer
Published in Journal of translational medicine (26-06-2024)“…The transforming growth factor-beta (TGF-[beta]) signaling pathway is a vital regulator of cell proliferation, differentiation, apoptosis, and extracellular…”
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Journal Article -
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Genetic and pharmacological intervention of the p75NTR pathway alters morphological and behavioural recovery following traumatic brain injury in mice
Published in Brain injury (02-01-2016)“…Primary objective: Neurotrophin levels are elevated after TBI, yet there is minimal regeneration. It was hypothesized that the pro-neurotrophin/p75NTR pathway…”
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The Effects of Genetic Polymorphisms on Recovery after Repeated Mild Traumatic Brain Injury in a Mouse Model and Personalized Treatment Approaches
Published 01-01-2019“…Traumatic Brain Injury (TBI) is a serious and potentially life-threatening clinical problem. In 2013, there were 2.5 million TBIs in the United States, 50,000…”
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