Search Results - "Giardullo, Paola"
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Phenotypic and Functional Characteristics of Exosomes Derived from Irradiated Mouse Organs and Their Role in the Mechanisms Driving Non-Targeted Effects
Published in International journal of molecular sciences (09-11-2020)“…Molecular communication between irradiated and unirradiated neighbouring cells initiates radiation-induced bystander effects (RIBE) and out-of-field (abscopal)…”
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2
Protocol for a systematic review of the in vivo studies on radiofrequency (100 kHz-300 GHz) electromagnetic field exposure and cancer
Published in Systematic reviews (16-02-2022)“…An Italian project aims to review the scientific literature on the possible carcinogenicity of radiofrequency (100 kHz-300 GHz) electromagnetic field (RF-EMF)…”
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3
Tomato Bushy Stunt Virus Nanoparticles as a Platform for Drug Delivery to Shh-Dependent Medulloblastoma
Published in International journal of molecular sciences (29-09-2021)“…Medulloblastoma (MB) is a primary central nervous system tumor affecting mainly young children. New strategies of drug delivery are urgent to treat MB and, in…”
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4
Micro-RNA and Proteomic Profiles of Plasma-Derived Exosomes from Irradiated Mice Reveal Molecular Changes Preventing Apoptosis in Neonatal Cerebellum
Published in International journal of molecular sciences (16-02-2022)“…Cell communication via exosomes is capable of influencing cell fate in stress situations such as exposure to ionizing radiation. In vitro and in vivo studies…”
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5
Out-of-Field Hippocampus from Partial-Body Irradiated Mice Displays Changes in Multi-Omics Profile and Defects in Neurogenesis
Published in International journal of molecular sciences (20-04-2021)“…The brain undergoes ionizing radiation exposure in many clinical situations, particularly during radiotherapy for brain tumors. The critical role of the…”
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Abscopal effect of radiation therapy: Interplay between radiation dose and p53 status
Published in International journal of radiation biology (01-03-2014)“…Abstract Purpose: This study investigates whether the abscopal effect induced by radiation-therapy (RT) is able to sterilize non-irradiated tumour cells…”
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Dose and Spatial Effects in Long-Distance Radiation Signaling In Vivo: Implications for Abscopal Tumorigenesis
Published in International journal of radiation oncology, biology, physics (01-03-2013)“…Purpose To investigate the dose and spatial dependence of abscopal radiation effects occurring in vivo in the mouse, along with their tumorigenic potential in…”
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Oncogenic Radiation Abscopal Effects In Vivo: Interrogating Mouse Skin
Published in International journal of radiation oncology, biology, physics (01-08-2013)“…Purpose To investigate the tissue dependence in transmission of abscopal radiation signals and their oncogenic consequences in a radiosensitive mouse model and…”
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9
N6-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response
Published in Redox biology (01-01-2014)“…N 6 -isopentenyladenosine (i 6 A), a naturally occurring modified nucleoside, inhibits the proliferation of human tumor cell lines in vitro , but its mechanism…”
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10
A Systematic Review on the In Vivo Studies on Radiofrequency (100 kHz-300 GHz) Electromagnetic Field Exposure and Co-Carcinogenesis
Published in International journal of environmental research and public health (02-08-2024)“…In this systematic review, the potential role of in vivo RF-EMF exposure combined with the administration of well-known carcinogens in tumor…”
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11
Microsecond Pulsed Electric Fields: An Effective Way to Selectively Target and Radiosensitize Medulloblastoma Cancer Stem Cells
Published in International journal of radiation oncology, biology, physics (01-04-2021)“…Cancer stem cells constitute an endless reserve for the maintenance and progression of tumors, and they could be the reason for conventional therapy failure…”
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12
A biodistribution study of two differently shaped plant virus nanoparticles reveals new peculiar traits
Published in Colloids and surfaces, B, Biointerfaces (01-12-2016)“…Biodistribution of two unmodified and differently shaped plant virus nanoparticles in murine organs [Display omitted] •Differently shaped unmodified TBSV and…”
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13
Low Dose of Dipotassium Glycyrrhizate Counteracts Atherosclerosis Progression in Apoe-/- Female Mice
Published in Journal of vascular research (01-10-2019)Get more information
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14
Nanog-driven cell-reprogramming and self-renewal maintenance in Ptch1+/− granule cell precursors after radiation injury
Published in Scientific reports (27-10-2017)“…Medulloblastoma (MB) is the most common pediatric brain tumor, comprising four distinct molecular variants, one of which characterized by activation of the…”
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15
Human Medulloblastoma Cell Lines: Investigating on Cancer Stem Cell-Like Phenotype
Published in Cancers (17-01-2020)“…Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Despite the progress of new treatments, the risk of recurrence, morbidity, and death…”
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16
The Patched 1 Tumor-Suppressor Gene Protects the Mouse Lens from Spontaneous and Radiation-Induced Cataract
Published in The American journal of pathology (2015)“…Age-related cataract is the most common cause of visual impairment. Moreover, traumatic cataracts form after injury to the eye, including radiation damage. We…”
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Nonlinear Radiation-Induced Cataract Using the Radiosensitive Ptch1+/– Mouse Model
Published in Radiation research (01-09-2016)“…While most of the evidence for radiation-induced late health effects relates to cancer, there has been increasing interest recently in the development of…”
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Acceleration of atherogenesis in ApoE-/- mice exposed to acute or low-dose-rate ionizing radiation
Published in Oncotarget (13-10-2015)“…There is epidemiological evidence for increased non-cancer mortality, primarily due to circulatory diseases after radiation exposure above 0.5 Sv. We evaluated…”
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19
MiRNA-Mediated Fibrosis in the Out-of-Target Heart following Partial-Body Irradiation
Published in Cancers (16-07-2022)“…Recent reports have shown a link between radiation exposure and non-cancer diseases such as radiation-induced heart disease (RIHD). Radiation exposures are…”
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Transgenerational inheritance of enhanced susceptibility to radiation-induced medulloblastoma in newborn Ptch1⁺/⁻ mice after paternal irradiation
Published in Oncotarget (03-11-2015)“…The hypothesis of transgenerational induction of increased cancer susceptibility after paternal radiation exposure has long been controversial because of…”
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