Search Results - "Giardini, Alessandra"

Thiocolchicine−Podophyllotoxin Conjugates:  Dynamic Libraries Based on Disulfide Exchange Reaction by Danieli, Bruno, Giardini, Alessandra, Lesma, Giordano, Passarella, Daniele, Peretto, Bruno, Sacchetti, Alessandro, Silvani, Alessandra, Pratesi, Graziella, Zunino, Franco

“…A dynamic combinatorial library of thiocolchicine−podophyllotoxin derivatives based on the disulfide bond exchange reaction is described. The influence of a…”
Get full text

An Unusual Case of Epigastric Pain: Two Causes for One Disease by Olivetti, Lucio, Giardini, Alessandra, Grassia, Roberto

Get full text

Inhibitors of tubulin polymerization: Synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III by Passarella, Daniele, Giardini, Alessandra, Peretto, Bruno, Fontana, Gabriele, Sacchetti, Alessandro, Silvani, Alessandra, Ronchi, Cristina, Cappelletti, Graziella, Cartelli, Daniele, Borlak, Jurgen, Danieli, Bruno

“…A series of novel hybrid compounds obtained by the attachment of anhydrovinblastine, vinorelbine, and vindoline to thiocolchicine, podophyllotoxin, and…”
Get full text

Discovery of Diaryl Imidazolidin-2-one Derivatives, a Novel Class of Muscarinic M3 Selective Antagonists (Part 1) by Peretto, Ilaria, Forlani, Roberto, Fossati, Claudia, Giardina, Giuseppe A. M, Giardini, Alessandra, Guala, Matilde, La Porta, Elena, Petrillo, Paola, Radaelli, Stefano, Radice, Luigi, Raveglia, Luca F, Santoro, Enza, Scudellaro, Roberta, Scarpitta, Francesca, Bigogno, Chiara, Misiano, Paola, Dondio, Giulio M, Rizzi, Andrea, Armani, Elisabetta, Amari, Gabriele, Civelli, Maurizio, Villetti, Gino, Patacchini, Riccardo, Bergamaschi, Marco, Delcanale, Maurizio, Salcedo, Carolina, Fernández, Andrés G, Imbimbo, Bruno P

“…Pharmacophore-based structural identification, synthesis, and structure−activity relationships of a new class of muscarinic M3 receptor antagonists, the diaryl…”
Get full text

Discovery of Diaryl Imidazolidin-2-one Derivatives, a Novel Class of Muscarinic M3 Selective Antagonists (Part 2) by Peretto, Ilaria, Fossati, Claudia, Giardina, Giuseppe A. M, Giardini, Alessandra, Guala, Matilde, La Porta, Elena, Petrillo, Paola, Radaelli, Stefano, Radice, Luigi, Raveglia, Luca F, Santoro, Enza, Scudellaro, Roberta, Scarpitta, Francesca, Cerri, Alberto, Menegon, Sergio, Dondio, Giulio M, Rizzi, Andrea, Armani, Elisabetta, Amari, Gabriele, Civelli, Maurizio, Villetti, Gino, Patacchini, Riccardo, Bergamaschi, Marco, Bassani, Franco, Delcanale, Maurizio, Imbimbo, Bruno P

“…Synthesis and biological activity of a novel class of quaternary ammonium salt muscarinic M3 receptor antagonists, showing high selectivity versus the M2…”
Get full text

Synthesis and Biological Evaluation of PaclitaxelThiocolchicine Hybrids by Danieli, Bruno, Giardini, Alessandra, Lesma, Giordano, Passarella, Daniele, Silvani, Alessandra, Appendino, Giovanni, Noncovich, Alain, Fontana, Gabriele, Bombardelli, Ezio, Sterner, Olov

“…The bifunctional taxoidcolchicinoid hybrids 6–8 were synthesized and evaluated in assays of cytotoxicity and tubulin assembly/disassembly. All compounds…”
Get full text

Concise total synthesis of (+/-)-aloperine and 6-epi-aloperine by Passarella, Daniele, Angoli, Marco, Giardini, Alessandra, Lesma, Giordano, Silvani, Alessandra, Danieli, Bruno

“…[reaction: see text] Total synthesis of aloperine and 6-epi-aloperine is reported. The crucial steps of the synthetic strategy are an aza-annulation reaction…”
Get full text

A convenient synthesis of Δ7,8-morphinan-6-one and its direct oxidation to 14-hydroxy-Δ7,8-morphinan-6-one by PASSARELLA, Daniele, CONSONNI, Alessandra, GIARDINI, Alessandra, LESMA, Giordano, SILVANI, Alessandra

Get full text

A Convenient Synthesis of Δ 7,8-Morphinan-6-one and Its Direct Oxidation to 14-Hydroxy-Δ 7,8-morphinan-6-one by Passarella, Daniele, Consonni, Alessandra, Giardini, Alessandra, Lesma, Giordano, Silvani, Alessandra

“…Synthesis of Δ 7,8-morphinan-6-one by Grewe cyclization and bromoketalization reaction as crucial steps is described. Introduction of a hydroxyl group at…”
Get full text

Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes by Passarella, Daniele, Favia, Raffaele, Giardini, Alessandra, Lesma, Giordano, Martinelli, Marisa, Silvani, Alessandra, Danieli, Bruno, Efange, Simon M.N, Mash, Deborah C

“…Synthesis of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes by cycloaddition and subsequent cross-coupling reaction is described. Binding affinity of these novel…”
Get full text

Concise Total Synthesis of (±)-Aloperine and 6-e pi-Aloperine by Passarella, Daniele, Angoli, Marco, Giardini, Alessandra, Lesma, Giordano, Silvani, Alessandra, Danieli, Bruno

“…Total synthesis of aloperine and 6-epi-aloperine is reported. The crucial steps of the synthetic strategy are an aza-annulation reaction and an intermolecular…”
Get full text

A convenient synthesis of delta(7,8)-morphinan-6-one and its direct oxidation to 14-hydroxy-delta(7,8)-morphinan-6-one by Passarella, Daniele, Consonni, Alessandra, Giardini, Alessandra, Lesma, Giordano, Silvani, Alessandra

“…Synthesis of Delta(7,8)-morphinan-6-one by Grewe cyclization and bromoketalization reaction as crucial steps is described. Introduction of a hydroxyl group at…”
Get full text