Search Results - "Gianutsos, Gerald"

Lack of role for the vanilloid receptor in response to several inspired irritant air pollutants in the C57Bl/6J mouse by Symanowicz, Peter T., Gianutsos, Gerald, Morris, John B.

“…Sensory irritants initiate respiratory reflexes by stimulating trigeminal sensory nerves. The vanilloid receptor (TRPV1) is expressed on sensory C fibers. The…”
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Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats by Mayorga, Arthur J, Cousins, Michael S, Trevitt, Jennifer T, Conlan, Aimee, Gianutsos, Gerald, Salamone, John D

“…Four muscarinic receptor antagonists with varying selectivities for the four pharmacologically-defined muscarinic receptor subtypes (M 1–M 4) were administered…”
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Effect of chronic imipramine or baclofen on GABA-B binding and cyclic AMP production in cerebral cortex by Suzdak, P D, Gianutsos, G

“…Long-term (14 days) treatment of mice with the antidepressant drug imipramine increased the number of GABA-B receptors in the cerebral cortex and also led to…”
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Preparation of Faculty Members and Students to Be Citizen Leaders and Pharmacy Advocates by Ross, Leigh Ann, Janke, Kristin K., Boyle, Cynthia J., Gianutsos, Gerald, Lindsey, Cameron C., Moczygemba, Leticia R., Whalen, Karen

“…To identify characteristics and quality indicators of best practices for leadership and advocacy development in pharmacy education, a national task force on…”
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Adenosine Sensory Transduction Pathways Contribute to Activation of the Sensory Irritation Response to Inspired Irritant Vapors by Vaughan, Ryan P., Szewczyk, Michael T., Lanosa, Michael J., DeSesa, Christopher R., Gianutsos, Gerald, Morris, John B.

“…The molecular mechanisms through which sensory irritants stimulate nasal trigeminal nerves are poorly understood. The current study was aimed at evaluating the…”
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Structure-anti-Parkinson activity relationships in the aminoadamantanes. Influence of bridgehead substitution by Henkel, James G, Hane, Jeffrey T, Gianutsos, Gerald

“…A limited series of bridgehead alkyl-, dialkyl-, and trialkyl-substituted amantadines was synthesized and tested for potential anti-Parkinson activity as…”
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Effect of loperamide, haloperidol and methadone in rats trained to discriminate morphine from saline by Gianutsos, G, Lal, H

“…In an operant procedure of lever pressing at FR10 schedule of food reinforcement, rats were trained to respond differentially in order to discriminate the…”
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Alteration of in vivo and in vitro effects of heroin by esterase inhibition by Gianutsos, G, Cohen, S D, Carlson, G, Heyman, R, Salva, P, Morrow, G, Hite, G J

“…Selective inhibition of peripheral esterases by tri-ortho-tolyl phosphate in the mouse resulted in an increase in the analgetic activity of heroin, without…”
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Sensory nerve-mediated immediate nasal responses to inspired acrolein by Morris, John B, Stanek, John, Gianutsos, Gerald

“…Toxicology Program, Department of Pharmaceutical Sciences, University of Connecticut, Storrs, Connecticut 06269-2092 To investigate the role of sensory C-fiber…”
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Pharmacological activity of amantadine: effect of N-alkyl substitution by Dunn, J P, Henkel, J G, Gianutsos, G

“…Alkyl substitution on the nitrogen atom of the anti-parkinsonian drug amantadine resulted in changes in its pharmacological potency. Greater behavioural…”
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Blockade of apomorphine-induced aggression by morphine or neuroleptics: differential alteration by antimuscarinics and naloxone by Gianutsos, G, Lal, H

“…Both morphine and the neuroleptics, haloperidol and oxyperomide, dose-dependently reduce the aggression in rats produced by 20 mg/kg of apomorphine, a dopamine…”
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Sulfate- and size-dependent polysaccharide modulation of AMPA receptor properties by Chicoine, Linda M., Suppiramaniam, Vishnu, Vaithianathan, Thirumalini, Gianutsos, Gerald, Bahr, Ben A.

“…Previous work found evidence that α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid (AMPA)‐type glutamate receptors interact with and are functionally…”
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An Evidence-Based Systematic Review of Passion Flower (Passiflora Incarnata L.) by the Natural Standard Research Collaboration by Ulbricht, Catherine, Basch, Ethan, Boon, Heather, Karpa, Kelly Dowhower, Gianutsos, Gerald, Nummy, Katie, Seamon, Erica, Smith, Michael, Sollars, David, Tanguay-Colucci, Shaina, Varghese, Minney, Weissner, Wendy, Woods, Jen

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Accumulation of Manganese in Rat Brain Following Intranasal Administration by Gianutsos, Gerald, Morrow, Gale R., Morris, John B.

“…Manganese chloride (50–800 μg) was injected unilaterally into the right nostril of rats and its accumulation in the central nervous system (CNS) was monitored…”
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Ethanol-induced suppression of cell-mediated immunity in the mouse by Jayasinghe, R, Gianutsos, G, Hubbard, A K

“…Among its many effects on multiple organ systems, ethanol abuse also elicits potent immunomodulatory effects as well. Increased susceptibility to disease as…”
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Repeated scopolamine injections sensitize rats to pilocarpine-induced vacuous jaw movements and enhance striatal muscarinic receptor binding by Baskin, P P, Gianutsos, G, Salamone, J D

“…This experiment was conducted to determine if repeated administration of the muscarinic antagonist scopolamine could increase pilocarpine-induced vacuous jaw…”
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Altered pilocarpine- or chlorpromazine-induced catalepsy after long-term treatment with cholinergic drugs by Gianutsos, G

“…Long-term administration of the cholinergic drug pilocarpine attenuates the catalepsy induced by an acute injection of pilocarpine or the deopamine antagonist…”
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Effects of imipramine and serotonin-2 agonists and antagonists on serotonin-2 and beta-adrenergic receptors following noradrenergic or serotonergic denervation by Eison, A S, Eison, M S, Yocca, F D, Gianutsos, G

“…The effects of chronic (14 day) administration of the tricyclic antidepressant imipramine, the serotonin-2 (5-HT2) antagonist ketanserin, and the serotonin…”
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Pharmacological changes in dopaminergic systems induced by long-term administration of amantadine by Gianutsos, G, Chute, S, Dunn, J P

“…The pharmacological effects of 6 weeks administration of amantadine was evaluated in the mouse. Motor stimulation induced by amphetamine or the amantadine…”
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Unique modulation of central 5-HT2 receptor binding sites and 5-HT2 receptor-mediated behavior by continuous gepirone treatment by Yocca, F D, Eison, A S, Hyslop, D K, Ryan, E, Taylor, D P, Gianutsos, G

“…The effect of continuous treatment with the selective 5-HT1A agonist gepirone upon 5-HT2-mediated behavior and cortical 5-HT2 receptor binding sites was…”
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