Search Results - "Gianotti, N."
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Rilpivirine plus cobicistat-boosted darunavir as a two-drug switch regimen in HIV-infected, virologically suppressed subjects on steady standard three-drug therapy: a randomized, controlled, non-inferiority trial (PROBE 2)
Published in Journal of antimicrobial chemotherapy (01-05-2020)“…Abstract Background We explored the combination of rilpivirine plus cobicistat-boosted darunavir [a two-drug regimen (2DR)] when switching from standard triple…”
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Switching from a Non-Protease Inhibitor-Based Regimen to the Fixed Dose Combination of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in Clinical Practice [Corrigendum]
Published in Drug design, development and therapy (30-11-2022)“…Ranzenigo M, Gianotti N, Galli L, et al. Drug Des Devel Ther. 2022;16:1975-1982. Page 1975, Abstract, Results, line five, the text "the ongoing regimen was…”
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Cardiovascular adverse events during treatment with darunavir-based regimens in an Italian observational study
Published in Drug design, development and therapy (01-01-2019)“…The protease inhibitor (PI) darunavir (DRV) has proven to be highly effective and well tolerated for HIV treatment. The DAD (Data collection on Adverse Effects…”
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Switching from tenofovir disoproxil fumarate to tenofovir alafenamide or dual therapy-based regimens in HIV-infected individuals with viral load ≤50 copies/mL: does estimated glomerular filtration rate matter?
Published in International journal of antimicrobial agents (01-12-2020)“…•Switching from tenofovir disoproxil fumarate (TDF)-containing regimens has increased considerably in recent years.•A high proportion of people with a…”
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Switching from a Non-Protease inhibitor-Based Regimen To the Fixed Dose Combination of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide in Clinical Practice
Published in Drug design, development and therapy (01-01-2022)“…Background: The primary objective of this study was to estimate the proportion of people living with HIV (PLWH) who switched from a non-protease inhibitor…”
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HIV DNA loads, plasma residual viraemia and risk of virological rebound in heavily treated, virologically suppressed HIV-infected patients
Published in Clinical microbiology and infection (01-01-2015)“…In this single-centre, retrospective study, we analyzed data of 194 patients receiving antiretroviral therapy with <50 human immunodeficiency virus (HIV) RNA…”
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Virological rebound in human immunodeficiency virus-infected patients with or without residual viraemia: results from an extended follow-up
Published in Clinical microbiology and infection (01-12-2013)“…Human immunodeficiency virus (HIV) -infected patients with HIV RNA loads of < 50 copies/mL were followed-up for a median (interquartile range) of 30.8…”
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Number of daily pills, dosing schedule, self‐reported adherence and health status in 2010: a large cross‐sectional study of HIV‐infected patients on antiretroviral therapy
Published in HIV medicine (01-03-2013)“…Objectives The aim of the study was to assess whether pill burden is associated with self‐reported adherence to current combination antiretroviral regimens and…”
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Evolution patterns of raltegravir-resistant mutations after integrase inhibitor interruption
Published in Clinical microbiology and infection (01-06-2011)“…The objective of this study was to address the evolution of human immunodeficiency virus type 1 (HIV-1) mutations resistant to the integrase inhibitor…”
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Prevalence of transmitted HIV-1 drug resistance in HIV-1-infected patients in Italy: evolution over 12 years and predictors
Published in Journal of antimicrobial chemotherapy (01-09-2009)“…Objectives Transmitted HIV-1 drug resistance (TDR) can reduce the efficacy of first-line antiretroviral therapy. Patients and methods A retrospective analysis…”
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Prevalence of etravirine (ETR)-RAMs at NNRTI failure and predictors of resistance to ETR in a large Italian resistance database (ARCA)
Published in Clinical microbiology and infection (01-10-2013)“…The prevalence of drug resistance associated with the failure of nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimens and the predictors of…”
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Human immunodeficiency virus-1 B and non-B subtypes with the same drug resistance pattern respond similarly to antiretroviral therapy
Published in Clinical microbiology and infection (01-03-2012)“…We analysed the 12-week virological response to protease inhibitor (PI) or non-nucleoside reverse transcriptase inhibitor (NNRTI) therapy in 1108 patients…”
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Detecting impaired glucose tolerance or type 2 diabetes mellitus by means of an oral glucose tolerance test in HIV‐infected patients
Published in HIV medicine (01-02-2011)“…Objective As a proactive diagnosis of diabetes mellitus (DM) may prevent the onset of severe complications, we used an oral glucose tolerance test (OGTT) to…”
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Comparison of a Rule-Based Algorithm with a Phenotype-Based Algorithm for the Interpretation of HIV Genotypes in Guiding Salvage Regimens in HIV-Infected Patients by a Randomized Clinical Trial: The Mutations and Salvage Study
Published in Clinical infectious diseases (15-05-2006)“…Background. There is still considerable uncertainty as to the best algorithm for interpreting human immunodeficiency virus (HIV) genotyping results. Methods. A…”
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Two Different Patterns of Mutations are Involved in the Genotypic Resistance Score for Atazanavir Boosted Versus Unboosted by Ritonavir in Multiple Failing Patients
Published in Infection (01-06-2009)“…Objectives: The protease inhibitor atazanavir (ATV) can be used either boosted by ritonavir (ATV300/r) or unboosted (ATV400). To date, however, genotypic…”
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Managing failure to antiretroviral drugs in HIV-1-infected patients
Published in International journal of immunopathology and pharmacology (01-01-2003)“…Managing failure to antiretroviral therapies implies the addressing of several issues: the clinical stage, the virological and the immunological response to…”
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Observational study on HIV-infected subjects failing HAART receiving tenofovir plus didanosine as NRTI backbone
Published in Infection (01-12-2007)“…We evaluated the efficacy of tenofovir (TDF) - and didanosine (ddI)-containing backbones in HIV-infected experienced subjects. We included in the study 245…”
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Once-daily saquinavir and ritonavir in treatment-experienced HIV-1-infected individuals
Published in The New microbiologica (01-01-2004)“…To assess the efficacy of 48 weeks' treatment with saquinavir 1600 mg and ritonavir 100 mg, both given once daily (SQVOD), in drug-experienced HIV-infected…”
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