Performing bone marrow biopsies with or without sedation: a comparison

Summary Although intravenous sedation (ISED) in addition to a local anaesthetic (LA) is commonly used in the performance of a bone marrow aspirate and trephine (BMAT), it is not clear under what circumstances and in which way sedation may be most beneficial. In this study, information was gathered u...

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Bibliographic Details
Published in:	Clinical and laboratory haematology Vol. 26; no. 3; pp. 201 - 204
Main Authors:	Giannoutsos, I., Grech, H., Maboreke, T., Morgenstern, G.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Science Ltd 01-06-2004
Subjects:	Adult Aged Anesthesia, Local Biopsy - adverse effects Bone Marrow - pathology Bone marrow biopsies Bone Marrow Examination - adverse effects comparison Conscious Sedation Female Hematologic Diseases - pathology Humans Male Middle Aged Pain - etiology Pain - prevention & control Pain Measurement Retrospective Studies safe sedation Surveys and Questionnaires
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Summary:	Summary Although intravenous sedation (ISED) in addition to a local anaesthetic (LA) is commonly used in the performance of a bone marrow aspirate and trephine (BMAT), it is not clear under what circumstances and in which way sedation may be most beneficial. In this study, information was gathered using a questionnaire, from 112 patients shortly after undergoing BMAT; the duration of the procedures and the length of the biopsy cores were measured and any complications noted. Most patients (68%) chose to receive LA only, and almost all (74/76) were happy with their decision. Patients who received sedation gave lower pain scores than patients receiving LA only (1 vs. 3) and were found to have lower levels of apprehension at the thought of having a repeat procedure. Patients having a repeat BMAT showed a slightly increased preference for having sedation compared with patients who were undergoing it for the first time. There is some concern that guidelines regarding the use of ISED for procedures other than BMAT are not always adhered to, and current practice may be best revealed by a large‐scale audit of sedation practice for the performance of BMAT. Patients should be given the choice of having ISED if the appropriate resources are available, but in most cases the additional small risk of receiving sedation can be avoided.
Bibliography:	istex:D72FEECC899C2F888D95B325F223156C055439E3 ark:/67375/WNG-LBD9H6RM-6 ArticleID:IJLH608 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0141-9854 1365-2257
DOI:	10.1111/j.1365-2257.2004.00608.x