Search Results - "Giannotti, Marina I."

Influence of Cholesterol on the Phase Transition of Lipid Bilayers: A Temperature-Controlled Force Spectroscopy Study by Redondo-Morata, Lorena, Giannotti, Marina I, Sanz, Fausto

“…Cholesterol (Chol) plays the essential function of regulating the physical properties of the cell membrane by controlling the lipid organization and phase…”
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Phosphorylation disrupts long-distance electron transport in cytochrome c by Gomila, Alexandre M. J., Pérez-Mejías, Gonzalo, Nin-Hill, Alba, Guerra-Castellano, Alejandra, Casas-Ferrer, Laura, Ortiz-Tescari, Sthefany, Díaz-Quintana, Antonio, Samitier, Josep, Rovira, Carme, De la Rosa, Miguel A., Díaz-Moreno, Irene, Gorostiza, Pau, Giannotti, Marina I., Lagunas, Anna

“…It has been recently shown that electron transfer between mitochondrial cytochrome c and the cytochrome c 1 subunit of the cytochrome bc 1 can proceed at…”
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Interrogation of Single Synthetic Polymer Chains and Polysaccharides by AFM-Based Force Spectroscopy by Giannotti, Marina I., Vancso, G. Julius

“…This contribution reviews selected mechanical experiments on individual flexible macromolecules using single‐molecule force spectroscopy (SMFS) based on atomic…”
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Impact of galactosylceramides on the nanomechanical properties of lipid bilayer models: an AFM-force spectroscopy study by Gumí-Audenis, Berta, Sanz, Fausto, Giannotti, Marina I

“…Galactosylceramides (GalCer) are glycosphingolipids bound to a monosaccharide group, responsible for inducing extensive hydrogen bonds that yield their…”
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pH-Responsive Polysaccharide-Based Polyelectrolyte Complexes As Nanocarriers for Lysosomal Delivery of Therapeutic Proteins by Giannotti, Marina I, Esteban, Olga, Oliva, Mireia, García-Parajo, María F, Sanz, Fausto

“…Nanopharmaceutics composed of a carrier and a protein have the potential to improve the activity of therapeutical proteins. Therapy for lysosomal diseases is…”
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Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders by Placci, Marina, Giannotti, Marina I., Muro, Silvia

“…[Display omitted] Lysosomes play a central role in cellular homeostasis and alterations in this compartment associate with many diseases. The most studied…”
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Direct Measurement of the Nanomechanical Stability of a Redox Protein Active Site and Its Dependence upon Metal Binding by Giannotti, Marina I, Cabeza de Vaca, Israel, Artés, Juan M, Sanz, Fausto, Guallar, Victor, Gorostiza, Pau

“…The structural basis of the low reorganization energy of cupredoxins has long been debated. These proteins reconcile a conformationally heterogeneous and…”
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Structure and Nanomechanics of Model Membranes by Atomic Force Microscopy and Spectroscopy: Insights into the Role of Cholesterol and Sphingolipids by Gumí-Audenis, Berta, Costa, Luca, Carlá, Francesco, Comin, Fabio, Sanz, Fausto, Giannotti, Marina I

“…Biological membranes mediate several biological processes that are directly associated with their physical properties but sometimes difficult to evaluate…”
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Understanding the effects of omega-3 fatty acid supplementation on the physical properties of brain lipid membranes by Longarzo, María L., Vázquez, Romina F., Bellini, María J., Zamora, Ricardo A., Redondo-Morata, Lorena, Giannotti, Marina I., Oliveira Jr, Osvaldo N., Fanani, María L., Maté, Sabina M.

“…A deficiency in omega-3 fatty acids (ω3 FAs) in the brain has been correlated with cognitive impairment, learning deficiencies, and behavioral changes. In this…”
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The Protein Matrix of Plastocyanin Supports Long-Distance Charge Transport with Photosystem I and the Copper Ion Regulates Its Spatial Span and Conductance by López-Ortiz, Manuel, Zamora, Ricardo A., Giannotti, Marina I., Gorostiza, Pau

“…Charge exchange is the fundamental process that sustains cellular respiration and photosynthesis by shuttling electrons in a cascade of electron transfer (ET)…”
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The surface charge of electroactive materials governs cell behaviour through its effect on protein deposition by Rodriguez-Lejarraga, Paula, Martin-Iglesias, Sara, Moneo-Corcuera, Andrea, Colom, Adai, Redondo-Morata, Lorena, Giannotti, Marina I., Petrenko, Viktor, Monleón-Guinot, Irene, Mata, Manuel, Silvan, Unai, Lanceros-Mendez, Senentxu

“…The precise mechanisms underlying the cellular response to static electric cues remain unclear, limiting the design and development of biomaterials that…”
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Light- and Redox-Dependent Force Spectroscopy Reveals that the Interaction between Plastocyanin and Plant Photosystem I Is Favored when One Partner Is Ready for Electron Transfer by Zamora, Ricardo A., López-Ortiz, Manuel, Sales-Mateo, Montserrat, Hu, Chen, Croce, Roberta, Maniyara, Rinu Abraham, Pruneri, Valerio, Giannotti, Marina I., Gorostiza, Pau

“…Photosynthesis is a fundamental process that converts photons into chemical energy, driven by large protein complexes at the thylakoid membranes of plants,…”
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Closed Mechanoelectrochemical Cycles of Individual Single-Chain Macromolecular Motors by AFM by Shi, Weiqing, Giannotti, Marina I, Zhang, Xi, Hempenius, Mark A, Schönherr, Holger, Vancso, G. Julius

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Dendrimersome Synthetic Cells Harbor Cell Division Machinery of Bacteria by Wagner, Anna M., Eto, Hiromune, Joseph, Anton, Kohyama, Shunshi, Haraszti, Tamás, Zamora, Ricardo A., Vorobii, Mariia, Giannotti, Marina I., Schwille, Petra, Rodriguez‐Emmenegger, Cesar

“…The integration of active cell machinery with synthetic building blocks is the bridge toward developing synthetic cells with biological functions and beyond…”
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Impact of Glycans on Lipid Membrane Dynamics at the Nanoscale Unveiled by Planar Plasmonic Nanogap Antennas and Atomic Force Spectroscopy by Winkler, Pamina M, Campelo, Felix, Giannotti, Marina I, Garcia-Parajo, Maria F

“…Lateral compartmentalization of the plasma membrane is a prominent feature present at multiple spatiotemporal scales that regulates key cellular functions. The…”
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Structural impact of cations on lipid bilayer models: nanomechanical properties by AFM-force spectroscopy by Redondo-Morata, Lorena, Giannotti, Marina I, Sanz, Fausto

“…Atomic Force Microscopy (AFM) has become an invaluable tool for studying the micro- and nanoworlds. As a stand-alone, high-resolution imaging technique and…”
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Casein interaction with lipid membranes: Are the phase state or charge density of the phospholipids affecting protein adsorption? by Crespo-Villanueva, Adrián, Gumí-Audenis, Berta, Sanz, Fausto, Artzner, Franck, Mériadec, Cristelle, Rousseau, Florence, Lopez, Christelle, Giannotti, Marina I., Guyomarc'h, Fanny

“…Casein micelles are ~200 nm electronegative particles that constitute 80 wt% of the milk proteins. During synthesis in the lactating mammary cells, caseins are…”
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Pulling lipid tubes from supported bilayers unveils the underlying substrate contribution to the membrane mechanics by Gumí-Audenis, Berta, Costa, Luca, Ferrer-Tasies, Lidia, Ratera, Imma, Ventosa, Nora, Sanz, Fausto, Giannotti, Marina I

“…Cell processes like endocytosis, membrane resealing, signaling and transcription involve conformational changes which depend on the chemical composition and…”
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Hierarchical Quatsome-RGD Nanoarchitectonic Surfaces for Enhanced Integrin-Mediated Cell Adhesion by Martínez-Miguel, Marc, Castellote-Borrell, Miquel, Köber, Mariana, Kyvik, Adriana R., Tomsen-Melero, Judit, Vargas-Nadal, Guillem, Muñoz, Jose, Pulido, Daniel, Cristóbal-Lecina, Edgar, Passemard, Solène, Royo, Miriam, Mas-Torrent, Marta, Veciana, Jaume, Giannotti, Marina I., Guasch, Judith, Ventosa, Nora, Ratera, Imma

“…The synthesis and study of the tripeptide Arg-Gly-Asp (RGD), the binding site of different extracellular matrix proteins, e.g., fibronectin and vitronectin,…”
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AFM-Based Force-Clamp Monitors Lipid Bilayer Failure Kinetics by Redondo-Morata, Lorena, Giannotti, Marina I, Sanz, Fausto

“…The lipid bilayer rupture phenomenon is here explored by means of atomic force microscopy (AFM)-based force clamp, for the first time to our knowledge, to…”
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