Search Results - "Giannoni, Federico"

Drug-Resistant Tuberculosis 2020: Where We Stand by Iacobino, Angelo, Fattorini, Lanfranco, Giannoni, Federico

“…The control of tuberculosis (TB) is hampered by the emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains, defined as resistant to at…”
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Mycobacterium tuberculosis Is Selectively Killed by Rifampin and Rifapentine in Hypoxia at Neutral pH by Iacobino, Angelo, Piccaro, Giovanni, Giannoni, Federico, Mustazzolu, Alessandro, Fattorini, Lanfranco

“…The activities of rifampin, rifapentine, bedaquiline, PA-824, clofazimine, nitazoxanide, isoniazid, amikacin, moxifloxacin, niclosamide, thioridazine, and…”
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Activities of Drug Combinations against Mycobacterium tuberculosis Grown in Aerobic and Hypoxic Acidic Conditions by PICCARO, Giovanni, GIANNONI, Federico, FILIPPINI, Perla, MUSTAZZOLU, Alessandro, FATTORINI, Lanfranco

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Activity of lipophilic and hydrophilic drugs against dormant and replicating Mycobacterium tuberculosis by Piccaro, Giovanni, Poce, Giovanna, Biava, Mariangela, Giannoni, Federico, Fattorini, Lanfranco

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Eradication of Drug-Tolerant Mycobacterium tuberculosis 2022: Where We Stand by Lanni, Alessio, Iacobino, Angelo, Fattorini, Lanfranco, Giannoni, Federico

“…The lungs of tuberculosis (TB) patients contain a spectrum of granulomatous lesions, ranging from solid and well-vascularized cellular granulomas to avascular…”
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Prevention of False Resistance Results Obtained in Testing the Susceptibility of Mycobacterium tuberculosis to Pyrazinamide with the Bactec MGIT 960 System Using a Reduced Inoculum by Piersimoni, Claudio, Mustazzolu, Alessandro, Giannoni, Federico, Bornigia, Stefano, Gherardi, Giancarlo, Fattorini, Lanfranco

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Activity of DNA-targeted C8-linked pyrrolobenzodiazepine–heterocyclic polyamide conjugates against aerobically and hypoxically grown Mycobacterium tuberculosis under acidic and neutral conditions by Iacobino, Angelo, Giannoni, Federico, Fattorini, Lanfranco, Brucoli, Federico

“…Mycobacterium tuberculosis ( Mtb ) is the aetiological agent of tuberculosis, the leading cause of death worldwide from a single infectious agent. Mtb is a…”
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Identification of Rv1133c (MetE) as a marker of Mycobacterium tuberculosis replication and as a highly immunogenic antigen with potential immunodiagnostic power by Iacobino, Angelo, Teloni, Raffaela, Mancone, Carmine, Facchiano, Francesco, Di Giamberardino, Alessandra, Senatore, Cinzia, Di Virgilio, Antonio, Lanni, Alessio, Giannoni, Federico, Nisini, Roberto, Mariotti, Sabrina

“…The immunization of mice with the sterile culture medium supernatants of (Mtb) H37Rv permitted the production of several monoclonal antibodies (mAbs) specific…”
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Mycobacterium tuberculosis gene expression at different stages of hypoxia-induced dormancy and upon resuscitation by Iona, Elisabetta, Pardini, Manuela, Mustazzolu, Alessandro, Piccaro, Giovanni, Nisini, Roberto, Fattorini, Lanfranco, Giannoni, Federico

“…The physiology of dormant Mycobacterium tuberculosis was studied in detail by examining the gene expression of 51 genes using quantitative…”
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Moxifloxacin Activates the SOS Response in Mycobacterium tuberculosis in a Dose- and Time-Dependent Manner by Iacobino, Angelo, Piccaro, Giovanni, Pardini, Manuela, Fattorini, Lanfranco, Giannoni, Federico

“…Previous studies on demonstrated that sub-minimum inhibitory concentration (MIC) of fluoroquinolones induced the SOS response, increasing drug tolerance. We…”
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Fighting tuberculosis by drugs targeting nonreplicating Mycobacterium tuberculosis bacilli by Iacobino, Angelo, Piccaro, Giovanni, Giannoni, Federico, Mustazzolu, Alessandro, Fattorini, Lanfranco

“…Current tuberculosis (TB) treatment requires 6 months of combination therapy with isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol for…”
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Activity of Drug Combinations against Mycobacterium abscessus Grown in Aerobic and Hypoxic Conditions by Lanni, Alessio, Borroni, Emanuele, Iacobino, Angelo, Russo, Cristina, Gentile, Leonarda, Fattorini, Lanfranco, Giannoni, Federico

“…Infections caused by Mycobacterium abscessus (Mab), an environmental non-tuberculous mycobacterium, are difficult to eradicate from patients with pulmonary…”
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Targeting dormant bacilli to fight tuberculosis by Fattorini, Lanfranco, Piccaro, Giovanni, Mustazzolu, Alessandro, Giannoni, Federico

“…Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), which kills about 2 million people annually. Furthermore, 2 billion…”
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Endogenous PGE2 promotes the induction of human Th17 responses by fungal β-glucan by Gagliardi, Maria Cristina, Teloni, Raffaela, Mariotti, Sabrina, Bromuro, Carla, Chiani, Paola, Romagnoli, Giulia, Giannoni, Federico, Torosantucci, Antonella, Nisini, Roberto

“…C. albicans β‐glucan induces PGE2 production by human DC and promotes Th17 cell expansion. The interaction of PAMPs with cells of the innate immune system…”
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Metronidazole plus Rifampin Sterilizes Long-Term Dormant Mycobacterium tuberculosis by IONA, Elisabetta, GIANNONI, Federico, PARDINI, Manuela, BRUNORI, Lara, OREFICI, Graziella, FATTORINI, Lanfranco

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Mycobacteria Exploit p38 Signaling To Affect CD1 Expression and Lipid Antigen Presentation by Human Dendritic Cells by Gagliardi, Maria Cristina, Teloni, Raffaela, Giannoni, Federico, Mariotti, Sabrina, Remoli, Maria Elena, Sargentini, Valeria, Videtta, Melissa, Pardini, Manuela, De Libero, Gennaro, Coccia, Eliana Marina, Nisini, Roberto

“…Group I CD1 proteins are specialized antigen-presenting molecules that present both microbial and self lipid antigens to CD1-restricted α/β T lymphocytes. The…”
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Evaluation of a New Line Probe Assay for Rapid Identification of gyrA Mutations in Mycobacterium tuberculosis by GIANNONI, Federico, IONA, Elisabetta, SEMENTILLI, Federica, BRUNORI, Lara, PARDINI, Manuela, BATTISTA MIGLIORI, Giovanni, OREFICI, Graziella, FATTORINI, Lanfranco

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Isolation of Nocardia asiatica from Cutaneous Ulcers of a Human Immunodeficiency Virus-Infected Patient in Italy by Iona, Elisabetta, Giannoni, Federico, Brunori, Lara, de Gennaro, Michele, Mattei, Romano, Fattorini, Lanfranco

“…A strain of Nocardia was isolated from cutaneous ulcers of a human immunodeficiency virus-infected patient in Italy. Comparative 16S rRNA gene sequence…”
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Mycobacterium bovis Bacillus Calmette-Guérin infects DC-SIGN– dendritic cell and causes the inhibition of IL-12 and the enhancement of IL-10 production by Gagliardi, Maria Cristina, Teloni, Raffaela, Giannoni, Federico, Pardini, Manuela, Sargentini, Valeria, Brunori, Lara, Fattorini, Lanfranco, Nisini, Roberto

“…The only available vaccine against tuberculosis is Mycobacterium bovis Bacillus Calmette Guérin (BCG), although its efficacy in preventing pulmonary…”
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Drug Resistance Evolution of a Mycobacterium tuberculosis Strain from a Noncompliant Patient by Meacci, Francesca, Orrù, Germano, Iona, Elisabetta, Giannoni, Federico, Piersimoni, Claudio, Pozzi, Gianni, Fattorini, Lanfranco, Oggioni, Marco R

“…The emergence and spread of multidrug-resistant (MDR) Mycobacterium tuberculosis (MT) represents a worldwide health care problem because of the difficulty in…”
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