Search Results - "Gianni, M"

Refine Results
  1. 1

    ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection by Zhou, Lingli, Xu, Zhenhua, Castiglione, Gianni M., Soiberman, Uri S., Eberhart, Charles G., Duh, Elia J.

    Published in The ocular surface (01-10-2020)
    “…Conjunctival signs and symptoms are observed in a subset of patients with COVID-19, and SARS-CoV-2 has been detected in tears, raising concerns regarding the…”
    Get full text
    Journal Article
  2. 2

    Evolutionary pathways to SARS-CoV-2 resistance are opened and closed by epistasis acting on ACE2 by Castiglione, Gianni M, Zhou, Lingli, Xu, Zhenhua, Neiman, Zachary, Hung, Chien-Fu, Duh, Elia J

    Published in PLoS biology (21-12-2021)
    “…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infects a broader range of mammalian species than previously predicted, binding a diversity of…”
    Get full text
    Journal Article
  3. 3

    Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds by Castiglione, Gianni M., Xu, Zhenhua, Zhou, Lingli, Duh, Elia J.

    Published in Nature communications (18-05-2020)
    “…Birds (Aves) display high metabolic rates and oxygen consumption relative to mammals, increasing reactive oxygen species (ROS) formation. Although excess ROS…”
    Get full text
    Journal Article
  4. 4

    Catastrophic slab loss in southwestern Pangea preserved in the mantle and igneous record by Gianni, Guido M., Navarrete, César R.

    Published in Nature communications (04-02-2022)
    “…The Choiyoi Magmatic Province represents a major episode of silicic magmatism in southwestern Pangea in the mid-Permian-Triassic, the origin of which remains…”
    Get full text
    Journal Article
  5. 5

    Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction by Bergeron, John J.M, Di Guglielmo, Gianni M, Dahan, Sophie, Dominguez, Michel, Posner, Barry I

    Published in Annual review of biochemistry (02-06-2016)
    “…Epidermal growth factor (EGF) and insulin receptor tyrosine kinases (RTKs) exemplify how receptor location is coupled to signal transduction. Extracellular…”
    Get full text
    Journal Article
  6. 6
  7. 7

    Acetylenic tricyclic bis-(cyano enone) interacts with Cys 374 of actin, a residue necessary for stress fiber formation and cell migration by Chan, Eddie, Dirk, Brennan S, Honda, Tadashi, Stathopulos, Peter B, Dikeakos, Jimmy D, Di Guglielmo, Gianni M

    “…The migratory and invasive potential of tumour cells relies on the actin cytoskeleton. We previously demonstrated that the tricyclic compound, TBE-31, inhibits…”
    Get full text
    Journal Article
  8. 8

    Prolonged proteasome inhibition antagonizes TGFβ1-dependent signalling by promoting the lysosomal-targeting of TGFβ receptors by Trelford, Charles B., Di Guglielmo, Gianni M.

    Published in Cellular signalling (01-10-2022)
    “…Impairing autophagy disrupts transforming growth factor beta 1 (TGFβ1) signalling and epithelial-mesenchymal transition (EMT) in non-small cell lung cancer…”
    Get full text
    Journal Article
  9. 9

    GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness by Zajac, Mateusz, Law, Jeffrey, Cvetkovic, Dragana Donna, Pampillo, Macarena, McColl, Lindsay, Pape, Cynthia, Di Guglielmo, Gianni M, Postovit, Lynne M, Babwah, Andy V, Bhattacharya, Moshmi

    Published in PloS one (28-06-2011)
    “…Kisspeptins (Kp), peptide products of the Kisspeptin-1 (KISS1) gene are endogenous ligands for a G protein-coupled receptor 54 (GPR54). Previous findings have…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Atypical Protein Kinase C Phosphorylates Par6 and Facilitates Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition by Gunaratne, Adrian, Thai, Boun L., Di Guglielmo, Gianni M.

    Published in Molecular and Cellular Biology (01-03-2013)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
    Get full text
    Journal Article
  12. 12
  13. 13

    Transforming growth factor-β in tumour development by Trelford, Charles B, Dagnino, Lina, Di Guglielmo, Gianni M

    Published in Frontiers in molecular biosciences (04-10-2022)
    “…Transforming growth factor-β (TGFβ) is a ubiquitous cytokine essential for embryonic development and postnatal tissue homeostasis. TGFβ signalling regulates…”
    Get full text
    Journal Article
  14. 14

    Network-guided modeling allows tumor-type independent prediction of sensitivity to all-trans-retinoic acid by Bolis, M., Garattini, E., Paroni, G., Zanetti, A., Kurosaki, M., Castrignanò, T., Garattini, S.K., Biancardi, F., Barzago, M.M., Gianni’, M., Terao, M., Pattini, L., Fratelli, M.

    Published in Annals of oncology (01-03-2017)
    “…All-trans-retinoic acid (ATRA) is a differentiating agent used in the treatment of acute-promyelocytic-leukemia (APL) and it is under-exploited in other…”
    Get full text
    Journal Article
  15. 15

    Ghost-arc geochemical anomaly at a spreading ridge caused by supersized flat subduction by Gianni, Guido M., Likerman, Jeremías, Navarrete, César R., Gianni, Conrado R., Zlotnik, Sergio

    Published in Nature communications (12-04-2023)
    “…The Southern Atlantic-Southwest Indian ridges (SASWIR) host mid-ocean ridge basalts with a residual subduction-related geochemical fingerprint (i.e., a…”
    Get full text
    Journal Article
  16. 16
  17. 17

    Scientific rationale and international obligations for protection of active hydrothermal vent ecosystems from deep-sea mining by Van Dover, C.L., Arnaud-Haond, S., Gianni, M., Helmreich, S., Huber, J.A., Jaeckel, A.L., Metaxas, A., Pendleton, L.H., Petersen, S., Ramirez-Llodra, E., Steinberg, P.E., Tunnicliffe, V., Yamamoto, H.

    Published in Marine policy (01-04-2018)
    “…There is increasing interest in mining minerals on the seabed, including seafloor massive sulfide deposits that form at hydrothermal vents. The International…”
    Get full text
    Journal Article
  18. 18

    Functional trade-offs and environmental variation shaped ancient trajectories in the evolution of dim-light vision by Castiglione, Gianni M, Chang, Belinda Sw

    Published in eLife (26-10-2018)
    “…Trade-offs between protein stability and activity can restrict access to evolutionary trajectories, but widespread epistasis may facilitate indirect routes to…”
    Get full text
    Journal Article
  19. 19

    Decorin Is a Novel VEGFR-2-Binding Antagonist for the Human Extravillous Trophoblast by Khan, Gausal A, Girish, Gannareddy V, Lala, Neena, Di Guglielmo, Gianni M, Lala, Peeyush K

    Published in Molecular endocrinology (Baltimore, Md.) (01-08-2011)
    “…Extravillous trophoblasts (EVT) of the human placenta invade the uterine decidua and its arteries to ensure successful placentation. We previously identified…”
    Get full text
    Journal Article
  20. 20

    Prevalence and Clinical History of Incidental, Asymptomatic Pulmonary Embolism: A Meta-Analysis by Dentali, F, Ageno, W, Becattini, C, Galli, L, Gianni, M, Riva, N, Imberti, D, Squizzato, A, Venco, A, Agnelli, G

    Published in Thrombosis research (01-06-2010)
    “…Abstract Context Recently, there has been an increasing number of reports of incidental pulmonary embolism (PE) in patients undergoing chest computer…”
    Get full text
    Journal Article