Search Results - "Giannetti, Catherine A."

Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures by Roden, Christine A, Dai, Yifan, Giannetti, Catherine A, Seim, Ian, Lee, Myungwoon, Sealfon, Rachel, McLaughlin, Grace A, Boerneke, Mark A, Iserman, Christiane, Wey, Samuel A, Ekena, Joanne L, Troyanskaya, Olga G, Weeks, Kevin M, You, Lingchong, Chilkoti, Ashutosh, Gladfelter, Amy S

“…Abstract Nucleocapsid protein (N-protein) is required for multiple steps in betacoronaviruses replication. SARS-CoV-2-N-protein condenses with specific viral…”
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Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper by Christy, Thomas W, Giannetti, Catherine A, Laederach, Alain, Weeks, Kevin M

“…SHAPE-JuMP is a concise strategy for identifying close-in-space interactions in RNA molecules. Nucleotides in close three-dimensional proximity are crosslinked…”
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SHAPE Probing Reveals Human rRNAs Are Largely Unfolded in Solution by Giannetti, Catherine A, Busan, Steven, Weidmann, Chase A, Weeks, Kevin M

“…Chemical probing experiments, coupled with empirically determined free energy change relationships, can enable accurate modeling of the secondary structures of…”
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Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP by Christy, Thomas W, Giannetti, Catherine A, Houlihan, Gillian, Smola, Matthew J, Rice, Greggory M, Wang, Jian, Dokholyan, Nikolay V, Laederach, Alain, Holliger, Philipp, Weeks, Kevin M

“…Higher-order structure governs function for many RNAs. However, discerning this structure for large RNA molecules in solution is an unresolved challenge. Here,…”
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SHAPE probing reveals human ribosomal RNAs are largely unfolded in solution by Giannetti, Catherine A., Busan, Steven, Weidmann, Chase A., Weeks, Kevin M.

“…Chemical probing experiments, coupled with empirically-determined free energy change relationships, can enable accurate modeling of the secondary structures of…”
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Efficient synthesis for each of the eight stereoisomers of the iminosugars lentiginosine and 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) by Liotta, Louis J., Antoine, Jessica, Brammer Basta, Leighanne A., Campbell, Andrew S., Cole, Gabrielle Y., Demick Brazile, Kristen A., Dogal Gardner, Natalie M., Fitzgerald, Megan E., Francois, Jean E.K., French, Brian M., Garafola, Sara L., Giannetti, Catherine A., Granatosky, Eve A., Harney, Alycen M., Hummel, James T., Joyce, Andrew P., Keylor, Mitchell H., Khubchandani, Jasmine A., Korzeniecki, Claudia, Lieberman, Diana C., Litterio, Joshua M., Maiorano, Madison O., Marshall, Jessica F., McCarthy, Kelly A., Mendes Vieira, Andreia, Miller, Ruby M., Morrison, Emily R., Moura, Steven P., Neumann, Dillon F., Oliveira, Aliza F., Pace, Nicholas J., Plouffe, Jodie X., Pomfret, Meredith N., Reardon, Katelyn N., Sheller-Miller, Samantha M., Smith, Michael J., Sullivan, Jessica L., Sweeney, Samantha W., Tougas, Kerstin L.

“…Herein, we describe the efficient, diastereoselective syntheses of the iminosugars 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) 1b, lentiginosine 3a, and the seven…”
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