Search Results - "Gianfaldoni, Giacomo"

Management of Paroxysmal Nocturnal Haemoglobinuria: a personal view by Luzzatto, Lucio, Gianfaldoni, Giacomo, Notaro, Rosario

“…Summary Paroxysmal nocturnal haemoglobinuria (PNH) is a serious form of acquired haemolytic anaemia with several features that make it unique, including the…”
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Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL) by Bassan, Renato, Spinelli, Orietta, Oldani, Elena, Intermesoli, Tamara, Tosi, Manuela, Peruta, Barbara, Rossi, Giuseppe, Borlenghi, Erika, Pogliani, Enrico M., Terruzzi, Elisabetta, Fabris, Pietro, Cassibba, Vincenzo, Lambertenghi-Deliliers, Giorgio, Cortelezzi, Agostino, Bosi, Alberto, Gianfaldoni, Giacomo, Ciceri, Fabio, Bernardi, Massimo, Gallamini, Andrea, Mattei, Daniele, Di Bona, Eros, Romani, Claudio, Scattolin, Anna Maria, Barbui, Tiziano, Rambaldi, Alessandro

“…Clinical risk classification is inaccurate in predicting relapse in adult patients with acute lymphoblastic leukemia, sometimes resulting in patients receiving…”
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Prognostic stratification in venetoclax-based acute myeloid leukemia treatments: the molecular prognostic risk signature tested in a real-world setting by Ciolli, Gaia, Piccini, Matteo, Mannelli, Francesco, Gianfaldoni, Giacomo, Scappini, Barbara, Fasano, Laura, Crupi, Francesca, Quinti, Elisa, Pasquini, Andrea, Caroprese, Jessica, Rotunno, Giada, Pancani, Fabiana, Signori, Leonardo, Maccari, Chiara, Vanderwert, Fiorenza I, Guglielmelli, Paola, Vannucchi, Alessandro M

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Quick complete response achievement with venetoclax and azacitidine in a case of relapsed disseminated blastic plasmacytoid dendritic cell neoplasm by Piccini, Matteo, Loscocco, Giuseppe Gaetano, Gianfaldoni, Giacomo, Grieco, Pietro, Palmieri, Giuseppina, Pilerci, Sofia, Scappini, Barbara, Bosi, Alberto

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Complement fraction 3 binding on erythrocytes as additional mechanism of disease in paroxysmal nocturnal hemoglobinuria patients treated by eculizumab by Risitano, Antonio M., Notaro, Rosario, Marando, Ludovica, Serio, Bianca, Ranaldi, Danilo, Seneca, Elisa, Ricci, Patrizia, Alfinito, Fiorella, Camera, Andrea, Gianfaldoni, Giacomo, Amendola, Angela, Boschetti, Carla, Di Bona, Eros, Fratellanza, Giorgio, Barbano, Filippo, Rodeghiero, Francesco, Zanella, Alberto, Iori, Anna Paola, Selleri, Carmine, Luzzatto, Lucio, Rotoli, Bruno

“…In paroxysmal nocturnal hemoglobinuria (PNH) hemolytic anemia is due mainly to deficiency of the complement regulator CD59 on the surface of red blood cells…”
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Effect of age and treatment on predictive value of measurable residual disease: implications for clinical management of adult patients with acute myeloid leukemia by Mannelli, Francesco, Piccini, Matteo, Bencini, Sara, Gianfaldoni, Giacomo, Peruzzi, Benedetta, Caporale, Roberto, Scappini, Barbara, Fasano, Laura, Quinti, Elisa, Ciolli, Gaia, Pasquini, Andrea, Crupi, Francesca, Pilerci, Sofia, Pancani, Fabiana, Signori, Leonardo, Tarantino, Danilo, Maccari, Chiara, Paradiso, Vivian, Annunziato, Francesco, Guglielmelli, Paola, Vannucchi, Alessandro M

“…Measurable residual disease (MRD) is a powerful predictor of outcome in acute myeloid leukemia. In the early phases of treatment, MRD refines initial disease…”
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CEBPA -double-mutated acute myeloid leukemia displays a unique phenotypic profile: a reliable screening method and insight into biological features by Mannelli, Francesco, Ponziani, Vanessa, Bencini, Sara, Bonetti, Maria Ida, Benelli, Matteo, Cutini, Ilaria, Gianfaldoni, Giacomo, Scappini, Barbara, Pancani, Fabiana, Piccini, Matteo, Rondelli, Tommaso, Caporale, Roberto, Gelli, Anna Maria Grazia, Peruzzi, Benedetta, Chiarini, Marco, Borlenghi, Erika, Spinelli, Orietta, Giupponi, Damiano, Zanghì, Pamela, Bassan, Renato, Rambaldi, Alessandro, Rossi, Giuseppe, Bosi, Alberto

“…Mutations in CCAAT/enhancer binding protein α ( ) occur in 5-10% of cases of acute myeloid leukemia. -double-mutated cases usually bear biallelic N- and…”
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Clinical significance of chromatin-spliceosome acute myeloid leukemia: a report from the Northern Italy Leukemia Group (NILG) randomized trial 02/06 by Caprioli, Chiara, Lussana, Federico, Salmoiraghi, Silvia, Cavagna, Roberta, Buklijas, Ksenija, Elidi, Lara, Zanghi', Pamela, Michelato, Anna, Delaini, Federica, Oldani, Elena, Intermesoli, Tamara, Grassi, Anna, Gianfaldoni, Giacomo, Mannelli, Francesco, Ferrero, Dario, Audisio, Ernesta, Terruzzi, Elisabetta, De Paoli, Lorella, Cattaneo, Chiara, Borlenghi, Erika, Cavattoni, Irene, Tajana, Monica, Scattolin, Anna Maria, Mattei, Daniele, Corradini, Paolo, Campiotti, Leonardo, Ciceri, Fabio, Bernardi, Massimo, Todisco, Elisabetta, Cortelezzi, Agostino, Falini, Brunangelo, Pavoni, Chiara, Bassan, Renato, Spinelli, Orietta, Rambaldi, Alessandro

“…Secondary acute myeloid leukemia (sAML) after myelodysplastic or myeloproliferative disorders is a high-risk category currently identified by clinical history…”
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Recent advances in biological and clinical aspects of paroxysmal nocturnal hemoglobinuria by LUZZATTO, Lucio, GIANFALDONI, Giacomo

“…The unique feature of paroxysmal nocturnal hemoglobinuria (PNH), a chronic disease with severe hemolytic anemia, is the presence of a population of blood cells…”
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Successful rechallenge with Erwinia chrysanthemi asparaginase after pegaspargase-induced hypertriglyceridemia: a case report by Ciolli, Gaia, Pasquini, Andrea, Mannelli, Francesco, Scappini, Barbara, Gianfaldoni, Giacomo, Quinti, Elisa, Fasano, Laura, Caroprese, Jessica, Crupi, Francesca, Vannucchi, Alessandro Maria, Piccini, Matteo

“…Polyethylene-glycolated -derived l-asparaginase (pegaspargase, pASP) is an essential component of paediatric-inspired regimens for the treatment of acute…”
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High cure rates in Burkitt lymphoma and leukemia: a Northern Italy Leukemia Group study of the German short intensive rituximab-chemotherapy program by Intermesoli, Tamara, Rambaldi, Alessandro, Rossi, Giuseppe, Delaini, Federica, Romani, Claudio, Pogliani, Enrico Maria, Pagani, Chiara, Angelucci, Emanuele, Terruzzi, Elisabetta, Levis, Alessandro, Cassibba, Vincenzo, Mattei, Daniele, Gianfaldoni, Giacomo, Scattolin, Anna Maria, Di Bona, Eros, Oldani, Elena, Parolini, Margherita, Gökbuget, Nicola, Bassan, Renato

“…We evaluate the long-term results of a prospective clinical study enrolling more than 100 adult patients with Burkitt lymphoma/leukemia. Depending on extent of…”
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P529: THE EFFECT OF AGE AND TREATMENT ON THE PREDICTIVE VALUE OF MEASURABLE RESIDUAL DISEASE: IMPLICATIONS FOR THE CLINICAL MANAGEMENT OF ADULT PATIENTS WITH ACUTE MYELOID LEUKEMIA by Mannelli, Francesco, Piccini, Matteo, Bencini, Sara, Gianfaldoni, Giacomo, Peruzzi, Benedetta, Caporale, Roberto, Scappini, Barbara, Fasano, Laura, Quinti, Elisa, Ciolli, Gaia, Pasquini, Andrea, Crupi, Francesca, Pilerci, Sofia, Pancani, Fabiana, Signori, Leonardo, Tarantino, Danilo, Maccari, Chiara, Paradiso, Vivian, Annunziato, Francesco, Guglielmelli, Paola, Maria Vannucchi, Alessandro

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CXCR4 expression accounts for clinical phenotype and outcome in acute myeloid leukemia by Mannelli, Francesco, Cutini, Ilaria, Gianfaldoni, Giacomo, Bencini, Sara, Scappini, Barbara, Pancani, Fabiana, Ponziani, Vanessa, Bonetti, Maria Ida, Biagiotti, Caterina, Longo, Giovanni, Bosi, Alberto

“…Background In acute myeloid leukemia (AML), CXCR4 expression has been correlated with leukocytosis and prognosis. Methods We quantified CXCR4 expression by…”
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Early reduction of WT1 transcripts during induction chemotherapy predicts for longer disease free and overall survival in acute myeloid leukemia by GIANFALDONI, Giacomo, MANNELLI, Francesco, PONZIANI, Vanessa, LONGO, Giovanni, BENCINI, Sara, BOSI, Alberto, VANNUCCHI, Alessandro M

“…We investigated the prognostic significance of early peripheral blast clearance as assessed by WT1 transcript reduction during the first days of standard…”
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Peripheral blood blast clearance during induction therapy in acute myeloid leukemia by Gianfaldoni, Giacomo, Mannelli, Francesco, Bencini, Sara, Leoni, Franco, Baldini, Simone, Bosi, Alberto

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CD20 expression has no prognostic role in Philadelphia-negative B-precursor acute lymphoblastic leukemia: new insights from the molecular study of minimal residual disease by MANNELLI, Francesco, GIANFALDONI, Giacomo, ROMANI, Claudio, CICERI, Fabio, CORTI, Consuelo, SCATTOLIN, Anna, CORTELEZZI, Agostino, MATTEI, Daniele, AUDISIO, Ernesta, SPINELLI, Orietta, OLDANI, Elena, BOSI, Alberto, INTERMESOLI, Tamara, RAMBALDI, Alessandro, BASSAN, Renato, CATTANEO, Chiara, BORLENGHI, Erika, CORTELAZZO, Sergio, CAVATTONI, Irene, MARIA POGLIANI, Enrico, FUMAGALLI, Monica, ANGELUCCI, Emanuele

“…The prognostic significance of CD20 expression in acute lymphoblastic leukemia has been investigated in children and adults but is still a subject of debate…”
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APL-like Subset within NPM1-Mutated Acute Myeloid Leukemia: A Distinct Phenotypic Signature Correlating with Early-Onset Vascular Complications by Crupi, Francesca, Ciolli, Gaia, Piccini, Matteo, Bencini, Sara, Gianfaldoni, Giacomo, Peruzzi, Benedetta, Caporale, Roberto, Scappini, Barbara, Fasano, Laura, Quinti, Elisa, Pasquini, Andrea, Caroprese, Jessica, Pancani, Fabiana, Signori, Leonardo, Maccari, Chiara, Paradiso, Vivian, Annunziato, Francesco, Guglielmelli, Paola, Vannucchi, Alessandro Maria, Mannelli, Francesco

“…Background:NPM1 mutations represent the most common genetic alteration in adult acute myeloid leukemia (AML), often in co-occurrence with FLT3-ITD and…”
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Venetoclax in Combination with Hypomethylating Agents or Low-Dose Cytarabine for Relapsed/Refractory Acute Myeloid Leukemia: A Retrospective Single-Centre Experience by Piccini, Matteo, Pilerci, Sofia, Scappini, Barbara, Mannelli, Francesco, Ciolli, Gaia, Pasquini, Andrea, Fasano, Laura, Quinti, Elisa, Guglielmelli, Paola, Mannarelli, Carmela, Pancani, Fabiana, Zizza, Michela, Signori, Leonardo, Vannucchi, Alessandro M., Gianfaldoni, Giacomo

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The Impact of Baseline Genetic Profile and Treatment on Hematological Toxicity in CEBPA-Mutated Acute Myeloid Leukemia by Mannelli, Francesco, Piccini, Matteo, Frigeni, Marco, Gianfaldoni, Giacomo, Bencini, Sara, Salmoiraghi, Silvia, Scappini, Barbara, Peruzzi, Benedetta, Caporale, Roberto, Ciolli, Gaia, Fasano, Laura, Crupi, Francesca, Quinti, Elisa, Pasquini, Andrea, Pilerci, Sofia, Vanderwert, Fiorenza, Rotunno, Giada, Pancani, Fabiana, Signori, Leonardo, Tarantino, Danilo, Maccari, Chiara, Paradiso, Vivian, Annunziato, Francesco, Spinelli, Orietta, Guglielmelli, Paola, Rambaldi, Alessandro, Vannucchi, Alessandro Maria

“…Background:CEBPA-mutated acute myeloid leukemia (AML) is a separate entity in the updated WHO and ICC classifications. Previously identified by double…”
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Selected Genomic Structural Variants Refine ELN-Based Prognostic Stratification of Patients with Acute Myeloid Leukemia and Normal Karyotype by Bartalucci, Niccolò, Mannelli, Francesco, Romagnoli, Simone, Tarantino, Danilo, Scappini, Barbara, Enderti, Alessio, Gianfaldoni, Giacomo, Irushani, Fiorenza, Piccini, Matteo, Salmoiraghi, Silvia, Ottone, Tiziana, Piciocchi, Alfonso, Orsi, Silvia, Vignetti, Marco, Civini, Alessia, Pavoni, Chiara, Bassan, Renato, Bortoluzzi, Stefania, Venditti, Adriano, Rambaldi, Alessandro, Voso, Maria Teresa, Guglielmelli, Paola, Vannucchi, Alessandro Maria

“…Background. Normal karyotype Acute Myeloid Leukemia (nk-AML) accounts for 40% of all AML. Conventionally, nk-AML patients (pts) have been associated with the…”
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