Search Results - "Giagulli, Cinzia"

Efficacy of COVID-19 mRNA vaccination in patients with autoimmune disorders: humoral and cellular immune response by Filippini, Federica, Giacomelli, Mauro, Bazzani, Chiara, Fredi, Micaela, Semeraro, Paolo, Tomasi, Cesare, Franceschini, Franco, Caruso, Arnaldo, Cavazzana, Ilaria, Giagulli, Cinzia

“…The impact of immunosuppressive therapies on the efficacy of vaccines to SARS-CoV-2 is not completely clarified. We analyzed humoral and T cell-mediated…”
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Role of HIV-1 matrix protein p17 variants in lymphoma pathogenesis by Dolcetti, Riccardo, Giagulli, Cinzia, He, Wangxiao, Selleri, Marina, Caccuri, Francesca, Eyzaguirre, Lindsay M., Mazzuca, Pietro, Corbellini, Silvia, Campilongo, Federica, Marsico, Stefania, Giombini, Emanuela, Muraro, Elena, Rozera, Gabriella, De Paoli, Paolo, Carbone, Antonino, Capobianchi, Maria Rosaria, Ippolito, Giuseppe, Fiorentini, Simona, Blattner, William A., Lu, Wuyuan, Gallo, Robert C., Caruso, Arnaldo

“…Although in decline after successful anti-HIV therapy, B-cell lymphomas are still elevated in HIV-1-seropositive (HIV+) persons, and the mechanisms are…”
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The Synthetic Dipeptide Pidotimod Shows a Chemokine-Like Activity through CXC Chemokine Receptor 3 (CXCR3) by Caccuri, Francesca, Bugatti, Antonella, Corbellini, Silvia, Roversi, Sara, Zani, Alberto, Mazzuca, Pietro, Marsico, Stefania, Caruso, Arnaldo, Giagulli, Cinzia

“…In recent years immunomodulators have gained a strong interest and represent nowadays an active expanding area of research for the control of microbial…”
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HIV-1 Matrix Protein p17 and its Receptors by Caccuri, Francesca, Marsico, Stefania, Fiorentini, Simona, Caruso, Arnaldo, Giagulli, Cinzia

“…The HIV-1 matrix protein p17 (p17) plays a crucial role in the virus life cycle. It is released in the extracellular space from HIV-1-infected cells and…”
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B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation by Giagulli, Cinzia, Caccuri, Francesca, Zorzan, Simone, Bugatti, Antonella, Zani, Alberto, Filippini, Federica, Manocha, Ekta, D’Ursi, Pasqualina, Orro, Alessandro, Dolcetti, Riccardo, Caruso, Arnaldo

“…Combined antiretroviral therapy (cART) for HIV-1 dramatically slows disease progression among HIV + individuals. Currently, lymphoma represents the main cause…”
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Regulation of conformer-specific activation of the integrin LFA-1 by a chemokine-triggered Rho signaling module by Laudanna, Carlo, Bolomini-Vittori, Matteo, Montresor, Alessio, Giagulli, Cinzia, Staunton, Donald, Rossi, Barbara, Martinello, Marianna, Constantin, Gabriela

“…Leukocyte adhesion is governed by the affinity state of integrin LFA-1. Laudanna and colleagues show that many Rho GTPase family members interact to form a…”
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HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2 by Caccuri, Francesca, Giagulli, Cinzia, Bugatti, Antonella, Benetti, Anna, Alessandri, Giulio, Ribatti, Domenico, Marsico, Stefania, Apostoli, Paola, Slevin, Mark A., Rusnati, Marco, Guzman, Carlos A., Fiorentini, Simona, Caruso, Arnaldo

“…Vascular diseases supported by aberrant angiogenesis have increased incidence in HIV-1-infected patients. Several data suggest that endothelium dysfunction…”
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An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking by Toffali, Lara, D’Ulivo, Beatrice, Giagulli, Cinzia, Montresor, Alessio, Zenaro, Elena, Delledonne, Massimo, Rossato, Marzia, Iadarola, Barbara, Sbarbati, Andrea, Bernardi, Paolo, Angelini, Gabriele, Rossi, Barbara, Lopez, Nicola, Linke, Wolfgang A., Unger, Andreas, Di Silvestre, Dario, Benazzi, Louise, De Palma, Antonella, Motta, Sara, Constantin, Gabriela, Mauri, Pierluigi, Laudanna, Carlo

“…Response to multiple microenvironmental cues and resilience to mechanical stress are essential features of trafficking leukocytes. Here, we describe unexpected…”
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Role of Autophagy in Von Willebrand Factor Secretion by Endothelial Cells and in the In Vivo Thrombin-Antithrombin Complex Formation Promoted by the HIV-1 Matrix Protein p17 by Bugatti, Antonella, Marsico, Stefania, Mazzuca, Pietro, Schulze, Kai, Ebensen, Thomas, Giagulli, Cinzia, Peña, Esther, Badimón, Lina, Slevin, Mark, Caruso, Arnaldo, Guzman, Carlos A, Caccuri, Francesca

“…Although the advent of combined antiretroviral therapy has substantially improved the survival of HIV-1-infected individuals, non-AIDS-related diseases are…”
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HIV-1 matrix protein p17 binds to the IL-8 receptor CXCR1 and shows IL-8–like chemokine activity on monocytes through Rho/ROCK activation by Giagulli, Cinzia, Magiera, Anna K., Bugatti, Antonella, Caccuri, Francesca, Marsico, Stefania, Rusnati, Marco, Vermi, William, Fiorentini, Simona, Caruso, Arnaldo

“…Exogenous HIV-1 matrix protein p17 was found to deregulate biologic activities of many different immune cells that are directly or indirectly involved in AIDS…”
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A single amino acid substitution confers B-cell clonogenic activity to the HIV-1 matrix protein p17 by Giagulli, Cinzia, D’Ursi, Pasqualina, He, Wangxiao, Zorzan, Simone, Caccuri, Francesca, Varney, Kristen, Orro, Alessandro, Marsico, Stefania, Otjacques, Benoît, Laudanna, Carlo, Milanesi, Luciano, Dolcetti, Riccardo, Fiorentini, Simona, Lu, Wuyuan, Caruso, Arnaldo

“…Recent data highlight the presence, in HIV-1-seropositive patients with lymphoma, of p17 variants (vp17s) endowed with B-cell clonogenicity, suggesting a role…”
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HIV-1 matrix protein p17: a candidate antigen for therapeutic vaccines against AIDS by Fiorentini, Simona, Giagulli, Cinzia, Caccuri, Francesca, Magiera, Anna K, Caruso, Arnaldo

“…The success in the development of anti-retroviral therapies (HAART) that contain human immunodeficiency virus type 1 (HIV-1) infection is challenged by the…”
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Opposite effects of HIV-1 p17 variants on PTEN activation and cell growth in B cells by Giagulli, Cinzia, Marsico, Stefania, Magiera, Anna K, Bruno, Rosalinda, Caccuri, Francesca, Barone, Ines, Fiorentini, Simona, Andò, Sebastiano, Caruso, Arnaldo

“…The HIV-1 matrix protein p17 is a structural protein that can act in the extracellular environment to deregulate several functions of immune cells, through the…”
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The Src Family Kinases Hck and Fgr Are Dispensable for Inside-Out, Chemoattractant-Induced Signaling Regulating β2 Integrin Affinity and Valency in Neutrophils, but Are Required for β2 Integrin-Mediated Outside-In Signaling Involved in Sustained Adhesion by Giagulli, Cinzia, Ottoboni, Linda, Caveggion, Elena, Rossi, Barbara, Lowell, Clifford, Constantin, Gabriela, Laudanna, Carlo, Berton, Giorgio

“…Abstract Neutrophil β2 integrins are activated by inside-out signaling regulating integrin affinity and valency; following ligand binding, β2 integrins trigger…”
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Successful CAR-T cell therapy in a refractory MCL patient with bacterial, fungal and COVID-19 infection: a case report by Radici, Vera, Giagulli, Cinzia, Accorsi Buttini, Eugenia, Farina, Mirko, Polverelli, Nicola, Brugnoni, Duilio, Chiarini, Marco, Galvagni, Anna, Almici, Camillo, Ferrari, Emilio, Bianchetti, Andrea, Masneri, Stefania, Leoni, Alessandro, Re, Federica, Bernardi, Simona, Malagola, Michele, Re, Alessandro, Caruso, Arnaldo, Russo, Domenico

“…The COVID-19 pandemic has had a significant impact on the management and care of onco-hematological patients, particularly those with lymphoproliferative…”
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HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness by Caccuri, Francesca, Giordano, Francesca, Barone, Ines, Mazzuca, Pietro, Giagulli, Cinzia, Andò, Sebastiano, Caruso, Arnaldo, Marsico, Stefania

“…The introduction of cART has changed the morbidity and mortality patterns affecting HIV-infected (HIV ) individuals. The risk of breast cancer in HIV patients…”
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Molecular Mechanisms Involved in Lymphocyte Recruitment in Inflamed Brain Microvessels: Critical Roles for P-Selectin Glycoprotein Ligand-1 and Heterotrimeric Gi-Linked Receptors by Piccio, Laura, Rossi, Barbara, Scarpini, Elio, Laudanna, Carlo, Giagulli, Cinzia, Issekutz, Andrew C, Vestweber, Dietmar, Butcher, Eugene C, Constantin, Gabriela

“…Abstract Lymphocyte recruitment into the brain is a critical event in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis. We…”
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Management of a Case of Peritonitis Due to Neisseria gonorrhoeae Infection Following Pelvic Inflammatory Disease (PID) by De Francesco, Maria A, Stefanelli, Paola, Carannante, Anna, Corbellini, Silvia, Giagulli, Cinzia, Lorenzin, Giovanni, Ronconi, Maurizio, Arici, Elisa, Cadei, Monica, Campora, Riccardo, Caruso, Arnaldo

“…Pelvic inflammatory disease (PID), a serious infection in sexually active women, is one of the reasons for which females seek care in emergency departments and…”
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Human Metapneumovirus Establishes Persistent Infection in Lung Microvascular Endothelial Cells and Primes a Th2-Skewed Immune Response by Bugatti, Antonella, Marsico, Stefania, Fogli, Manuela, Roversi, Sara, Messali, Serena, Bosisio, Daniela, Giagulli, Cinzia, Caruso, Arnaldo, Sozzani, Silvano, Fiorentini, Simona, Caccuri, Francesca

“…Human Metapneumovirus (HMPV) is a major cause of lower respiratory tract infections. HMPV infection has been hypothesized to alter dendritic cell (DC) immune…”
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RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones by Della Peruta, Marco, Giagulli, Cinzia, Laudanna, Carlo, Scarpa, Aldo, Sorio, Claudio

“…Our understanding of the mechanism regulating pancreatic cancer metastatic phenotype is limited. We analyzed the role of RHOA and PRKCZ in the motility…”
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