Search Results - "Giacoletto, KS"

Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation by Cross, A H, Girard, T J, Giacoletto, K S, Evans, R J, Keeling, R M, Lin, R F, Trotter, J L, Karr, R W

“…T cell activation involves not only recognition of antigen presented by the MHC, but also nonspecific interactions termed "costimulation." The costimulatory…”
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Delivery of nascent MHC class II-invariant chain complexes to lysosomal compartments and proteolysis of invariant chain by cysteine proteases precedes peptide binding in B-lymphoblastoid cells by Morton, PA, Zacheis, ML, Giacoletto, KS, Manning, JA, Schwartz, BD

“…The intracellular trafficking, proteolysis, and dissociation of invariant chain (li) associated with nascent class II molecules was examined in…”
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Differential effects of CTLA-4 substitutions on the binding of human CD80 (B7-1) and CD86 (B7-2) by Morton, P A, Fu, X T, Stewart, J A, Giacoletto, K S, White, S L, Leysath, C E, Evans, R J, Shieh, J J, Karr, R W

“…CTLA-4 expressed on activated T cells binds to CD80 (B7-1) and CD86 (B7-2) molecules present on APC with high avidity and appears to deliver a negative…”
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Peptide binding to surface class II molecules is the major pathway of formation of immunogenic class II-peptide complexes for viable antigen presenting cells by Nygard, NR, Giacoletto, KS, Bono, C, Gorka, J, Kompelli, S, Schwartz, BD

“…Although studies on fixed APCs have demonstrated that peptide can bind to cell surface class II molecules, the mechanisms by which peptide-class II complexes…”
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Invariant chain is the core protein of the Ia-associated chondroitin sulfate proteoglycan by SANT, A. J, CULLEN, S. E, GIACOLETTO, K. S, SCHWARTZ, B. D

“…The murine Ia-associated chondroitin sulfate proteoglycan (CSPG) was studied both biochemically and immunochemically to determine the nature of its core…”
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The human invariant chain is the core protein of the human class II-associated proteoglycan by GIACOLETTO, K. S, SANT, A. J, BONO, C, GORKA, J, O'SULLIVAN, D. M, QUARANTA, V, SCHWARTZ, B. D

“…The human class II-associated chondroitin sulfate proteoglycan (CSPG) was analyzed biochemically and immunologically to determine a possible relationship with…”
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Antibody recognition of an immunogenic influenza hemagglutinin-human leukocyte antigen class II complex by Nygard, N R, Bono, C, Brown, L R, Gorka, J, Giacoletto, K S, Schaiff, W T, Graham, M B, McCourt, D W, Kabeer, M, Braciale, V L

“…The A/Japan/57 influenza hemagglutin (HA) peptide HA 128-145, when bound by human histocompatibility leukocyte antigen-DRw11 cells, is recognized by the human…”
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Glycosaminoglycan modifications of membrane proteins by Giacoletto, K S, Rumbarger, T, Schwartz, B D

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Human Ia alpha- and beta-chains are sulfated by Sant, AJ, Zacheis, M, Rumbarger, T, Giacoletto, KS, Schwartz, BD

“…The human Ia antigens (DR, DQ, and DP), determined by genes with the HLA complex, are heterodimers consisting of a 34,000-Da alpha-chain glycoprotein and a…”
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