Search Results - "Giacchello, Ilaria"

Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents by Giacchello, Ilaria, Musumeci, Francesca, D'Agostino, Ilaria, Greco, Chiara, Grossi, Giancarlo, Schenone, Silvia

“…Influenza is a seasonal disease that affects millions of people every year and has a significant economic impact. Vaccines are the best strategy to fight this…”
Get more information

An Update on JAK Inhibitors by Musumeci, Francesca, Greco, Chiara, Giacchello, Ilaria, Fallacara, Anna Lucia, Ibrahim, Munjed M, Grossi, Giancarlo, Brullo, Chiara, Schenone, Silvia

“…Janus kinases (JAKs) are a family of non-receptor tyrosine kinases, composed by four members, JAK1, JAK2, JAK3 and TYK2. JAKs are involved in different…”
Get more information

Exploring a New Generation of Pyrimidine and Pyridine Derivatives as Anti-Influenza Agents Targeting the Polymerase PA-PB1 Subunits Interaction by Giacchello, Ilaria, Cianciusi, Annarita, Bertagnin, Chiara, Bonomini, Anna, Francesconi, Valeria, Mori, Mattia, Carbone, Anna, Musumeci, Francesca, Loregian, Arianna, Schenone, Silvia

“…The limited range of available flu treatments due to virus mutations and drug resistance have prompted the search for new therapies. RNA-dependent RNA…”
Get full text

Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction by D'Agostino, Ilaria, Giacchello, Ilaria, Nannetti, Giulio, Fallacara, Anna Lucia, Deodato, Davide, Musumeci, Francesca, Grossi, Giancarlo, Palù, Giorgio, Cau, Ylenia, Trist, Iuni Margaret, Loregian, Arianna, Schenone, Silvia, Botta, Maurizio

“…The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant…”
Get full text

Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors by Musumeci, Francesca, Sanna, Monica, Greco, Chiara, Giacchello, Ilaria, Fallacara, Anna Lucia, Amato, Rosario, Schenone, Silvia

“…Btk is a tyrosine kinase dysregulated in several B-cell malignancies and autoimmune diseases, and this has given rise to a search for Btk inhibitors…”
Get more information