Search Results - "Giaccari, A."

Management of diabetes in older adults by Sesti, G., Antonelli Incalzi, R., Bonora, E., Consoli, A., Giaccari, A., Maggi, S., Paolisso, G., Purrello, F., Vendemiale, G., Ferrara, N.

“…Type 2 diabetes prevalence is high in older adults and is expected to rise in the next decades. Diabetes in the population of frail older adults is accompanied…”
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Glucose toxicity: The leading actor in the pathogenesis and clinical history of type 2 diabetes – mechanisms and potentials for treatment by Giaccari, A, Sorice, G, Muscogiuri, G

“…Abstract Aim Although it is now well established that the deleterious effects of chronic hyperglycaemia (i.e., glucose toxicity) play an important role in the…”
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Effectiveness of oral semaglutide on glucose control and body weight up to 18 months: a multicenter retrospective real-world study by Bonora, B. M., Russo, G., Leonetti, F., Strazzabosco, M., Nollino, L., Aimaretti, G., Giaccari, A., Broglio, F., Consoli, A., Avogaro, A., Fadini, G. P.

“…Aim Oral semaglutide, an innovative orally administered GLP-1 receptor agonist for type 2 diabetes (T2D) management was herein evaluated for its effectiveness…”
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Noradrenergic fibers are associated with beta-cell dedifferentiation and impaired beta-cell function in humans by Cinti, F., Mezza, T., Severi, I., Suleiman, M., Cefalo, C.M.A., Sorice, G.P., Moffa, S., Impronta, F., Quero, G., Alfieri, S., Mari, A., Pontecorvi, A., Marselli, L., Cinti, S., Marchetti, P., Giaccari, A.

“…Type 2 diabetes (T2D) is characterized by a progressive loss of beta-cell function, and the “disappearance” of beta-cells in T2D may also be caused by the…”
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Vitamin D deficiency: a new risk factor for type 2 diabetes? by Mezza, T, Muscogiuri, G, Sorice, G P, Prioletta, A, Salomone, E, Pontecorvi, A, Giaccari, A

“…Recent compelling evidence suggests a role of vitamin D deficiency in the pathogenesis of insulin resistance and insulin secretion derangements, with a…”
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Can vitamin D deficiency cause diabetes and cardiovascular diseases? Present evidence and future perspectives by Muscogiuri, G, Sorice, G.P, Ajjan, R, Mezza, T, Pilz, S, Prioletta, A, Scragg, R, Volpe, S.L, Witham, M.D, Giaccari, A

“…Abstract Several studies have shown that vitamin D may play a role in many biochemical mechanisms in addition to bone and calcium metabolism. Recently, vitamin…”
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Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population by Bonadonna, R.C., Giaccari, A., Buzzetti, R., Aimaretti, G., Cucinotta, D., Avogaro, A., Perseghin, G., Larosa, M., Bolli, G.B., Fanelli, C.G.

“…Fostering patient's self-managing of basal insulin therapy could improve glucose control, by removing patient's and physician's barriers to basal insulin…”
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Corrigendum to “Italian Titration Approach Study (ITAS) with insulin glargine 300 U/mL in insulin-naïve type 2 diabetes: Design and population” [Nutr Metabol Cardiovasc Dis 29 (5) (May 2019) 496–503] by Bonadonna, R.C., Giaccari, A., Buzzetti, R., Aimaretti, G., Cucinotta, D., Avogaro, A., Perseghin, G., Larosa, M., Bolli, G.B., Fanelli, C.G.

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A consensus statement for the clinical use of the renal sodium-glucose co-transporter-2 inhibitor dapagliflozin in patients with type 2 diabetes mellitus by Avogaro, A, Giaccari, A, Fioretto, P, Genovese, S, Purrello, F, Giorgino, F, Del Prato, S

“…The present review developed a clinical consensus based on a Delphi method on Dapagliflozin, a selective inhibitor of the renal sodium-glucose co-transporter-2…”
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Early insulin treatment in type 2 diabetes: ORIGINal sin or valuable choice as ORIGINal treatment? An open debate on the ORIGIN study results by Bolli, G.B, Consoli, A, Giaccari, A

“…Abstract Diabetes is ultimately the result of relative or absolute insulin deficiency; insulin should therefore represent its “natural” treatment, from the…”
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In anorexia nervosa, even a small increase in abdominal fat is responsible for the appearance of insulin resistance by Prioletta, A., Muscogiuri, G., Sorice, G.P., Lassandro, A.P., Mezza, T., Policola, C., Salomone, E., Cipolla, C., Della Casa, S., Pontecorvi, A., Giaccari, A.

“…Summary Context  The aim of treatment in patients affected by anorexia nervosa (AN) is weight recovery. However, during weight gain, anorectic patients’ body…”
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Metabolic syndrome in subjects at high risk for type 2 diabetes: The genetic, physiopathology and evolution of type 2 diabetes (GENFIEV) study by Bianchi, C, Miccoli, R, Bonadonna, R.C, Giorgino, F, Frontoni, S, Faloia, E, Marchesini, G, Dolci, M.A, Alviggi, L, Gnasso, A, Consoli, A, Cavalot, F, Cavallo, M.G, Leonetti, F, Giaccari, A, Del Prato, S

“…Abstract Background and Aim We evaluated the relationship between insulin resistance (IR) and insulin secretion with the metabolic syndrome (MS) in 885…”
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Metabolic Syndrome in Transplant Patients: An Academic or a Health Burden? by Sorice, G.P, Muscogiuri, G, Mezza, T, Prioletta, A, Giaccari, A

“…Abstract Metabolic syndrome is a cluster of risk factors that predispose to major cardiovascular diseases, liver steatosis and fibrosis, as well as reduced…”
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P5.2 Diagnosis of early myelin involvement in diabetes as first sign of polyneuropathy: single fiber conduction velocity test by Padua, L, Stålberg, E, Caliandro, P, Muscogiuri, G, Pazzaglia, C, Sorice, G.P, Granata, G, Salomone, E, Pontecorvi, A, Giaccari, A

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Effects of glucosamine infusion on insulin secretion and insulin action in humans by MONAUNI, T, ZENTI, M. G, MUGGEO, M, BONORA, E, BONADONNA, R. C, CRETTI, A, DANIELS, M. C, TARGHER, G, CARUSO, B, CAPUTO, M, MCCLAIN, D, DEL PRATO, S, GIACCARI, A

“…Effects of glucosamine infusion on insulin secretion and insulin action in humans. T Monauni , M G Zenti , A Cretti , M C Daniels , G Targher , B Caruso , M…”
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Glucose toxicity by Rossetti, L, Giaccari, A, DeFronzo, R A

“…Glucose toxicity. L Rossetti , A Giaccari and R A DeFronzo Department of Medicine, University of Texas Health, San Antonio 78284. Abstract Glucose toxicity is…”
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Transgenic mice with dominant negative PKC-theta in skeletal muscle: A new model of insulin resistance and obesity by Serra, C., Federici, M., Buongiorno, A., Senni, M.I., Morelli, S., Segratella, E., Pascuccio, M., Tiveron, C., Mattei, E., Tatangelo, L., Lauro, R., Molinaro, M., Giaccari, A., Bouché, Marina

“…Protein kinase C θ (PKC‐θ) is the PKC isoform predominantly expressed in skeletal muscle, and it is supposed to mediate many signals necessary for muscle…”
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CA-125: Méta-analyse des essais de phase 3a EDITION sur un an, concernant le contrôle glycémique et l'hypoglycémie des patients diabétiques de type 2 (DT2) sous insuline glargine 300 U/mL (Gla-300) vs insuline glargine 100 U/mL (Gla-100) by Roussel, R, Giaccari, A, Vora, J, Grisoni, M, Brulle-Wohlheter, C, Glezer, S, Yki-Järvinen, H, Ritzel, R

“…Introduction Les essais de phase 3a EDITION 1, 2 et 3 ont comparé la nouvelle Gla-300 à la Gla-100 chez des patients DT2 Patients et Méthodes Méta-analyse des…”
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Role of physicians’ misperceived cardiovascular risk and therapeutic inertia in LDL-cholesterol targets achievement in diabetes by Morieri, M.L., Lamacchia, O., Manzato, E., Giaccari, A., Avogaro, A.

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In vivo effects of glucosamine on insulin secretion and insulin sensitivity in the rat : possible relevance to the maladaptive responses to chronic hyperglycaemia by GIACCARI, A, MORVIDUCCI, L, ZORRETTA, D, SBRACCIA, P, LEONETTI, F, CAIOLA, S, BUONGIORNO, A, BONADONNA, R. C, TAMBURRANO, G

“…We tested the hypothesis that glucosamine, a putative activator of glucose toxicity in vitro through acceleration of the hexosamine pathway, may determine in…”
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