Search Results - "Ghyczy, Miklós"
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The anti-inflammatory effects of methane
Published in Critical care medicine (01-04-2012)“…OBJECTIVE:Gastrointestinal methane generation has been demonstrated in various stress conditions, but it is not known whether nonasphyxiating amounts have any…”
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2
Enhanced formation of methane in plant cell cultures by inhibition of cytochrome c oxidase
Published in Plant, cell and environment (01-03-2011)“…The claim of methane (CH₄) formation in plants has caused much controversy and debate within the scientific community over the past 4 years. Here, using both…”
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3
Protective effects of L-alpha-glycerylphosphorylcholine on ischaemia–reperfusion-induced inflammatory reactions
Published in European journal of nutrition (01-02-2015)“…PURPOSE: Choline-containing dietary phospholipids, including phosphatidylcholine (PC), may function as anti-inflammatory substances, but the mechanism remains…”
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Anti-inflammatory effects of phosphatidylcholine in neutrophil leukocyte-dependent acute arthritis in rats
Published in European journal of pharmacology (10-11-2009)“…We investigated the effects of exogenous phosphatidylcholine (PC) and non-steroidal diclofenac supplementation on polymorphonuclear cell influx in…”
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5
Methane biogenesis during sodium azide-induced chemical hypoxia in rats
Published in American Journal of Physiology: Cell Physiology (15-01-2013)“…Previous studies demonstrated methane generation in aerobic cells. Our aims were to investigate the methanogenic features of sodium azide (NaN(3))-induced…”
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Radio-neuroprotective effect of L-alpha-glycerylphosphorylcholine (GPC) in an experimental rat model
Published in Journal of neuro-oncology (01-09-2014)“…Ionizing radiation plays a major role in the treatment of brain tumors, but side-effects may restrict the efficacy of therapy. In the present study, our goals…”
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Reduced mucosal side-effects of acetylsalicylic acid after conjugation with tris-hydroxymethyl-aminomethane. Synthesis and biological evaluation of a new anti-inflammatory compound
Published in European journal of pharmacology (15-06-2016)“…Acetylsalicylic acid (ASA) causes adverse haemorrhagic reactions in the upper gastrointestinal (GI) tract, and previous results have suggested that combination…”
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8
Hypoxia-Induced Generation of Methane in Mitochondria and Eukaryotic Cells - An Alternative Approach to Methanogenesis
Published in Cellular physiology and biochemistry (01-01-2008)“…Background/Aims: Electrophilic methyl groups bound to positively charged nitrogen moieties may act as electron acceptors, and this mechanism could lead to the…”
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Dietary phosphatidylcholine supplementation attenuates inflammatory mucosal damage in a rat model of experimental colitis
Published in Shock (Augusta, Ga.) (01-08-2012)“…This study was designed to follow the time course of inflammatory activation in a rodent model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis. We…”
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Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis
Published in Inflammopharmacology (01-02-2018)“…Background We have developed a novel compound from acetylsalicylic acid (ASA) and 2-amino-2-(hydroxymethyl)-1,3-propanediol (Tris) precursors with ASA-like…”
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11
Protective effects of a phosphatidylcholine-enriched diet in lipopolysaccharide-induced experimental neuroinflammation in the rat
Published in Shock (Augusta, Ga.) (01-11-2011)“…Our goal was to characterize the neuroprotective properties of orally administered phosphatidylcholine (PC) in a rodent model of systemic inflammation…”
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12
Oral phosphatidylcholine pretreatment decreases ischemia-reperfusion-induced methane generation and the inflammatory response in the small intestine
Published in Shock (Augusta, Ga.) (01-11-2008)“…We have shown that phosphatidylcholine (PC) metabolites may have a function in counteracting the production of reactive oxygen species (ROS), and that this…”
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13
Electrophilic methyl groups present in the diet ameliorate pathological states induced by reductive and oxidative stress: a hypothesis
Published in British journal of nutrition (01-04-2001)“…Reductive stress, characterised by an increased NADH:NAD+ ratio, may be as common and as important a consequence of redox imbalance as oxidative stress. It may…”
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14
Peripheral inflammatory activation after hippocampus irradiation in the rat
Published in International journal of radiation biology (01-01-2014)“…Abstract Purpose: To detect the possible biochemical signs of inflammatory activation in the peripheral circulation in a rodent model of hippocampus…”
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Simultaneous generation of methane, carbon dioxide, and carbon monoxide from choline and ascorbic acid ‐ a defensive mechanism against reductive stress?
Published in The FASEB journal (01-06-2003)“…ABSTRACT Indirect evidence suggests that an abnormal increase in reducing power (reductive stress) may be associated with abnormal clinical states. We have…”
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16
Characterization of the antiinflammatory properties of methane inhalation during ischaemia-reperfusion
Published in Magyar sebészet (01-08-2012)“…Gastrointestinal methane generation has been demonstrated in various conditions, but it is not known whether it has any impact on the mammalian physiology or…”
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Comparative study of novel therapeutic possibilities in animal experimental model of inflammatory bowel disease
Published in Magyar sebészet (01-08-2012)“…The consequence of inflammatory bowel diseases (IBD) is cytokine-mediated severe local tissue damage. Our aim was to determine the extent of inflammatory…”
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PHOSPHATIDYLCHOLINE TREATMENT AMELIORATES INTESTINAL MICROCIRCULATORY DERANGEMENT IN CANINE ENDOTOXEMIA: 247
Published in Shock (Augusta, Ga.) (01-03-2004)Get full text
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Evidence in support of a concept of reductive stress - Reply by Ghyczy & Boros
Published in British journal of nutrition (01-01-2002)Get full text
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Characterization of peroxidase secretion and subcellular organization of Phanerochaete chrysosporium INA-12 in the presence of various soybean phospholipid fractions
Published in Applied and Environmental Microbiology (01-12-1990)“…Stimulation of lignin peroxidase production by exogenous phospholipids depends on the composition of the phospholipid fraction prepared by using the Nattermann…”
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