Search Results - "Ghugre, Nilesh R."

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias by Romagnuolo, Rocco, Masoudpour, Hassan, Porta-Sánchez, Andreu, Qiang, Beiping, Barry, Jennifer, Laskary, Andrew, Qi, Xiuling, Massé, Stéphane, Magtibay, Karl, Kawajiri, Hiroyuki, Wu, Jun, Valdman Sadikov, Tamilla, Rothberg, Janet, Panchalingam, Krishna M., Titus, Emily, Li, Ren-Ke, Zandstra, Peter W., Wright, Graham A., Nanthakumar, Kumaraswamy, Ghugre, Nilesh R., Keller, Gordon, Laflamme, Michael A.

“…Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show considerable promise for regenerating injured hearts, and we therefore tested their capacity…”
Get full text

Practical medical applications of quantitative MR relaxometry by Margaret Cheng, Hai-Ling, Stikov, Nikola, Ghugre, Nilesh R., Wright, Graham A.

“…Conventional MR images are qualitative, and their signal intensity is dependent on several complementary contrast mechanisms that are manipulated by the MR…”
Get full text

Augmenting Performance: A Systematic Review of Optical See-Through Head-Mounted Displays in Surgery by Doughty, Mitchell, Ghugre, Nilesh R., Wright, Graham A.

“…We conducted a systematic review of recent literature to understand the current challenges in the use of optical see-through head-mounted displays (OST-HMDs)…”
Get full text

Relaxivity-iron calibration in hepatic iron overload: Probing underlying biophysical mechanisms using a Monte Carlo model by Ghugre, Nilesh R., Wood, John C.

“…Iron overload is a serious condition for patients with β‐thalassemia, transfusion‐dependent sickle cell anemia, and inherited disorders of iron metabolism. MRI…”
Get full text

Head-Mounted Display-Based Augmented Reality for Image-Guided Media Delivery to the Heart: A Preliminary Investigation of Perceptual Accuracy by Doughty, Mitchell, Ghugre, Nilesh R

“…By aligning virtual augmentations with real objects, optical see-through head-mounted display (OST-HMD)-based augmented reality (AR) can enhance user-task…”
Get full text

Quantitative tracking of edema, hemorrhage, and microvascular obstruction in subacute myocardial infarction in a porcine model by MRI by Ghugre, Nilesh R., Ramanan, Venkat, Pop, Mihaela, Yang, Yuesong, Barry, Jennifer, Qiang, Beiping, Connelly, Kim A., Dick, Alexander J., Wright, Graham A.

“…Pathophysiological responses after acute myocardial infarction include edema, hemorrhage, and microvascular obstruction along with cellular damage. The in vivo…”
Get full text

Hemorrhage promotes inflammation and myocardial damage following acute myocardial infarction: insights from a novel preclinical model and cardiovascular magnetic resonance by Ghugre, Nilesh R, Pop, Mihaela, Thomas, Reuben, Newbigging, Susan, Qi, Xiuling, Barry, Jennifer, Strauss, Bradley H, Wright, Graham A

“…Myocardial hemorrhage is a frequent complication following reperfusion in acute myocardial infarction and is predictive of adverse outcomes. However, it…”
Get full text

Editorial for “Prognostic Value of Segmental Strain After ST‐Elevation Myocardial Infarction: Insights From the EARLY Assessment of MYOcardial Tissue Characteristics by Cardiac Magnetic Resonance (EARLY‐MYO‐CMR) Study” by Ghugre, Nilesh R.

Get full text

Non-contrast assessment of microvascular integrity using arterial spin labeled cardiovascular magnetic resonance in a porcine model of acute myocardial infarction by Do, Hung P, Ramanan, Venkat, Qi, Xiuling, Barry, Jennifer, Wright, Graham A, Ghugre, Nilesh R, Nayak, Krishna S

“…Following acute myocardial infarction (AMI), microvascular integrity and function may be compromised as a result of microvascular obstruction (MVO) and…”
Get full text

Stem cell-derived cardiomyocytes expressing a dominant negative pacemaker HCN4 channel do not reduce the risk of graft-related arrhythmias by Wulkan, Fanny, Romagnuolo, Rocco, Qiang, Beiping, Valdman Sadikov, Tamilla, Kim, Kyung-Phil, Quesnel, Elya, Jiang, Wenlei, Andharia, Naaz, Weyers, Jill J, Ghugre, Nilesh R, Ozcan, Bilgehan, Alibhai, Faisal J, Laflamme, Michael A

“…Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) show tremendous promise for cardiac regeneration following myocardial infarction (MI), but their…”
Get full text

Suspected subclinical myocarditis detected by cardiac magnetic resonance imaging late post COVID-19 recovery by Ghugre, Nilesh R., Orbach, Ady, Biswas, Labonny, Connelly, Kim A., Chan, Adrienne, Strauss, Bradley H., Wright, Graham A., Roifman, Idan

“…There is growing evidence of the potential for cardiac involvement in patients who have been infected with COVID-19. In this case study, we present a patient…”
Get full text

MRI detects myocardial iron in the human heart by Ghugre, Nilesh R., Enriquez, Cathleen M., Gonzalez, Ignacio, Nelson Jr, Marvin D., Coates, Thomas D., Wood, John C.

“…Iron‐induced cardiac dysfunction is a leading cause of death in transfusion‐dependent anemia. MRI relaxation rates R2(1/T2) and R 2*(1/T 2*) accurately predict…”
Get full text

Comparison of the Frequencies of Myocardial Edema Determined by Cardiac Magnetic Resonance in Diabetic Versus Nondiabetic Patients Having Percutaneous Coronary Intervention for ST Elevation Myocardial Infarction by Zia, Mohammad I., MD, Ghugre, Nilesh R., PhD, Roifman, Idan, MD, Strauss, Bradley H., MD, PhD, Walcarius, Rhonda, MRT (MR), Mohammed, Malaika, BAS, Sparkes, John D., MSc, Dick, Alexander J., MD, Wright, Graham A., PhD, Connelly, Kim A., MD, PhD

“…The specific mechanisms by which diabetes may affect the myocardial tissue response to ischemia are unclear. Our objective was to prospectively quantify the…”
Get full text

Mechanisms of tissue-iron relaxivity: Nuclear magnetic resonance studies of human liver biopsy specimens by Ghugre, Nilesh R., Coates, Thomas D., Nelson, Marvin D., Wood, John C.

“…MRI is becoming an increasingly important tool to assess iron overload disorders, but the complex nature of proton–iron interactions has troubled noninvasive…”
Get full text

HMD-EgoPose: head-mounted display-based egocentric marker-less tool and hand pose estimation for augmented surgical guidance by Doughty, Mitchell, Ghugre, Nilesh R.

“…Purpose The success or failure of modern computer-assisted surgery procedures hinges on the precise six-degree-of-freedom (6DoF) position and orientation…”
Get full text

T1 and T2 mapping reveal contribution of hemorrhage in myocardial remodeling following acute myocardial infarction by Ghugre, Nilesh R, Ramanan, Venkat, Assimopoulos, Stephania, Qi, Xiuling, Barry, Jennifer, Strauss, Bradley H, Wright, Graham A

Get full text

Implications of disturbances in circadian rhythms for cardiovascular health: A new frontier in free radical biology by Khaper, Neelam, Bailey, Craig D.C., Ghugre, Nilesh R., Reitz, Cristine, Awosanmi, Zikra, Waines, Ryan, Martino, Tami A.

“…Cell autonomous circadian “clock” mechanisms are present in virtually every organ, and generate daily rhythms that are important for normal physiology. This is…”
Get full text

Evaluating a novel accelerated free-breathing late gadolinium enhancement imaging sequence for assessment of myocardial injury by Bhatt, Nitish, Orbach, Ady, Biswas, Labonny, Strauss, Bradley H., Connelly, Kim, Ghugre, Nilesh R., Wright, Graham A., Roifman, Idan

“…Cardiac magnetic resonance imaging (MRI), including late gadolinium enhancement (LGE), plays an important role in the diagnosis and prognostication of ischemic…”
Get full text

Thrombus aspiration during primary percutaneous coronary intervention is associated with reduced myocardial edema, hemorrhage, microvascular obstruction and left ventricular remodeling by Zia, Mohammad I, Ghugre, Nilesh R, Connelly, Kim A, Joshi, Subodh B, Strauss, Bradley H, Cohen, Eric A, Wright, Graham A, Dick, Alexander J

“…Thrombus aspiration (TA) has been shown to improve microvascular perfusion during primary percutaneous coronary intervention (PCI) for patients with ST-segment…”
Get full text

Quantification of fibrosis in infarcted swine hearts by ex vivo late gadolinium-enhancement and diffusion-weighted MRI methods by Pop, Mihaela, Ghugre, Nilesh R, Ramanan, Venkat, Morikawa, Lily, Stanisz, Greg, Dick, Alexander J, Wright, Graham A

“…Many have speculated that MRI signal characteristics can be used to identify regions of heterogeneous infarct associated with an arrhythmogenic substrate;…”
Get more information