Search Results - "Ghotra, Veerander P.S"
-
1
Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens
Published in Biomaterials (01-01-2012)“…Abstract Cell spheroids (CS) embedded in 3D extracellular matrix (ECM) serve as in vitro mimics for multicellular structures in vivo . Such cultures, started…”
Get full text
Journal Article -
2
Targeted radiosensitization in prostate cancer
Published in Current pharmaceutical design (2013)“…Radiotherapy is one of the treatment options for locally or regionally advanced prostate cancer, but radioresistance of prostate cancer cells is a practical…”
Get more information
Journal Article -
3
Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model
Published in The Journal of pathology (01-08-2012)“…Inhibition of VEGF signalling effectively suppresses localized tumour growth but accelerates tumour invasiveness and micrometastasis by unknown mechanisms. To…”
Get full text
Journal Article -
4
β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer
Published in Science signaling (11-02-2014)“…Interactions with the extracellular matrix (ECM) through integrin adhesion receptors provide cancer cells with physical and chemical cues that act together…”
Get more information
Journal Article -
5
SYK is a candidate kinase target for the treatment of advanced prostate cancer
Published in Cancer research (Chicago, Ill.) (01-01-2015)“…Improved targeted therapies are needed to combat metastatic prostate cancer. Here, we report the identification of the spleen kinase SYK as a mediator of…”
Get full text
Journal Article -
6
Automated whole animal bio-imaging assay for human cancer dissemination
Published in PloS one (08-02-2012)“…A quantitative bio-imaging platform is developed for analysis of human cancer dissemination in a short-term vertebrate xenotransplantation assay. Six days…”
Get full text
Journal Article