Search Results - "Ghosn, Bilal"

In vivo targeting of alveolar macrophages via RAFT-based glycopolymers by Song, Eun-Ho, Manganiello, Matthew J, Chow, Yu-Hua, Ghosn, Bilal, Convertine, Anthony J, Stayton, Partick S, Schnapp, Lynn M, Ratner, Daniel M

“…Abstract Targeting cell populations via endogenous carbohydrate receptors is an appealing approach for drug delivery. However, to be effective, this strategy…”
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Enhancing polysaccharide-mediated delivery of nucleic acids through functionalization with secondary and tertiary amines by Ghosn, Bilal, Kasturi, Sudhir Pai, Roy, Krishnendu

“…Chitosan is a polysaccharide that has generated significant interest as a non-viral gene delivery vehicle due to its cationic and biocompatible…”
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Efficient gene silencing in lungs and liver using imidazole-modified chitosan as a nanocarrier for small interfering RNA by Ghosn, Bilal, Singh, Ankur, Li, Mu, Vlassov, Alexander V, Burnett, Chris, Puri, Nitin, Roy, Krishnendu

“…Despite high specificity and potency, small interfering RNA (siRNA)-based therapeutics have been limited by their poor biostability and intracellular…”
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Efficient Modulation of T-cell Response by Dual-mode, Single-carrier Delivery of Cytokine-targeted siRNA and DNA Vaccine to Antigen-presenting Cells by Singh, Ankur, Nie, Hui, Ghosn, Bilal, Qin, Hong, Kwak, Larry W, Roy, Krishnendu

“…Controlled modulation of T-cell response during immunotherapy, especially the balance between T helper 1 (Th1) and Th2 responses, is critical for generating…”
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Encapsulation of nucleic acids and opportunities for cancer treatment by BRANNON-PEPPAS, Lisa, GHOSN, Bilal, ROY, Krishnendu, CORNETTA, Kenneth

“…The development of nucleic acid drugs for the treatment of various cancers has shown great promise in recent years. However, efficient delivery of these drugs…”
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Control of DNA Hybridization with Photocleavable Adducts by Ghosn, Bilal, Haselton, Frederick R., Gee, Kyle R., Monroe, W. Todd

“…Previous reports have shown that 1-(4,5-dimethoxy-2-nitrophenyl)ethyl ester (DMNPE) adducts coupled to DNA plasmids block transcription in vitro and in vivo…”
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Efficient mucosal delivery of optical contrast agents using imidazole-modified chitosan by Ghosn, Bilal, van de Ven, Anne L, Tam, Justina O, Gillenwater, Ann M, Sokolov, Konstantin V, Richards-Kortum, Rebecca R, Roy, Krishnendu

“…The clinical applicability of antibodies and plasmonic nanosensors as topically applied, molecule-specific optical diagnostic agents for noninvasive early…”
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Development and evaluation of an imidazole-modified chitosan for nucleic acid and contrast agent delivery by Ghosn, Bilal

“…Over the past several decades, gene therapy technologies have been developed for a diverse number of applications ranging from DNA-based vaccines to gene…”
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623. Polymer Microparticles Delivering a Idiotype/Chemokine Fusion DNA Vaccine Generate Protective Immunity in a Mice Model of B Cell Lymphoma by Kasturi, Sudhir P., Ghosn, Bilal, Thomson, Kassandra S., Qin, Hong, Kwak, Larry, Roy, Krishnendu

“…Introduction:We earlier demonstrated that branched Polyethyleneimine (PEI) conjugated poly(lactide-co-glycolide)PLGA microparticles enhanced transfection in…”
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Control of DNA Hybridization with Photocleavable Adducts by Ghosn, Bilal, Haselton, Frederick R., Gee, Kyle R., Monroe, W. Todd

“…ABSTRACT Previous reports have shown that 1‐(4,5‐dimethoxy‐2‐nitro‐phenyl)ethyl ester (DMNPE) adducts coupled to DNA plasmids block transcription in vitro and…”
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Control of DNA Hybridization with Photocleavable Adducts by Ghosn, Bilal, Haselton, Frederick R., Gee, Kyle R., Monroe, W. Todd

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Development and evaluation of an imidazole-modified chitosan for nucleic acid and contrast agent delivery by Ghosn, Bilal

“…Over the past several decades, gene therapy technologies have been developed for a diverse number of applications ranging from DNA-based vaccines to gene…”
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Photo-Control of DNA Oligonucleotides with Cage Compounds by Ghosn, Bilal

“…Many biochemical processes in which DNA and other nucleic acids participate are central to functions in both living cells and in molecular biology assays…”
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