Search Results - "Ghoshal, Kakali"

Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis by Ghoshal, Kakali, Bhattacharyya, Maitree

“…Platelets are small anucleate cell fragments that circulate in blood playing crucial role in managing vascular integrity and regulating hemostasis. Platelets…”
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Adiponectin: Probe of the molecular paradigm associating diabetes and obesity by Ghoshal, Kakali, Bhattacharyya, Maitree

“…Type 2 diabetes is an emerging health challenge all over the world as a result of urbanization, high prevalence of obesity, sedentary lifestyle and other…”
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Adiponectin Genetic Variant and Expression Coupled with Lipid Peroxidation Reveal New Signatures in Diabetic Dyslipidemia by Ghoshal, Kakali, Chatterjee, Tanima, Chowdhury, Subhankar, Sengupta, Sanghamitra, Bhattacharyya, Maitree

“…Increasing burden of non-communicable diseases like diabetes and cardiovascular disorders has made the global health scenario more challenging. Dyslipidemia in…”
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Detection of HSO3 –: A Rapid Colorimetric and Fluorimetric Selective Sensor for Detecting Biological SO2 in Food and Living Cells by Paul, Sima, Ghoshal, Kakali, Bhattacharyya, Maitree, Maiti, Dilip K

“…A rapid fluorescent probe based on the conjugate of chromone and benzothiazole moiety was presented, which could selectively respond to HSO3 – over other…”
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Cardiac Adipocytes: Friends or Foes? by Ghoshal, Kakali

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Aggregation-induced emission switch showing high contrast mehanofluorochromism and solvatofluorochromism: Specifically detects HSO3− in bioimaging studies by Das, Sangita, Das, Partha Pratim, Walton, James W., Quah, Ching Kheng, Ghoshal, Kakali, Bhattacharyya, Maitree

“…In this work, a novel mechanoresponsive luminescent (MRL) and aggregation induced emission (AIE) switch,…”
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Development of a new fluorescence ratiometric switch for endogenous hypochlorite detection in monocytes of diabetic subjects by dye release method by Das, Sangita, Aich, Krishnendu, Patra, Lakshman, Ghoshal, Kakali, Gharami, Saswati, Bhattacharyya, Maitree, Mondal, Tapan Kumar

“…A new quinoline-diaminomaleonitrile based probe was synthesised for the selective and ratiometric endogenous screening of OCl− in living diabetic blood cells…”
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Human peripheral blood mononuclear cells targeted multidimensional switch for selective detection of HSO3− anion by Das, Sangita, Das, Partha Pratim, Walton, James W., Ghoshal, Kakali, Patra, Lakshman, Bhattacharyya, Maitree, Mondal, Tapan Kumar, Thomas, Sabu

“…A new ratiometric π-conjugated luminophore with donor-acceptor (D- π- A) network CM {(E)-2-(4-(2-(9-butyl-9H-carbazol-3-yl)vinyl)benzylidine)malononitrile} has…”
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Epoxygenase Cyp2c44 Regulates Hepatic Lipid Metabolism and Insulin Signaling by Controlling FATP2 Localization and Activation of the DAG/PKCδ Axis by Ghoshal, Kakali, Luther, James M, Pakala, Suman B, Chetyrkin, Sergei, Falck, John R, Zent, Roy, Wasserman, David H, Pozzi, Ambra

“…Cytochrome P450 epoxygenase Cyp2c44, a murine epoxyeicosatrienoic acid (EET)-producing enzyme, promotes insulin sensitivity, and Cyp2c44-/- mice show hepatic…”
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Dielectric properties of plasma membrane: A signature for dyslipidemia in diabetes mellitus by Ghoshal, Kakali, Chakraborty, Subhadip, Das, Chirantan, Chattopadhyay, Sanatan, Chowdhury, Subhankar, Bhattacharyya, Maitree

“…Dielectric properties of a living biological membrane play crucial role indicating the status of the cell in pathogenic or healthy condition. A distinct…”
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294-OR: Hepatic Integrin ß1 Subunit Is Required for Liver Insulin Resistance but Not Fatty Liver in Diet-Induced Obese Mice by TREFTS, ELIJAH, GHOSHAL, KAKALI, DO, ALLISON V., GUERIN, AMANDA, GUAN, CHRISTOPHER, BRACY, DEANNA, LANTIER, LOUISE, ZENT, ROY, POZZI, AMBRA, WASSERMAN, DAVID H.

“…Obesity can lead to liver fibrosis and a selective insulin resistance whereby insulin-stimulated lipogenesis is maintained and liver triglycerides (TG) are…”
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EET Analog Treatment Improves Insulin Signaling in a Genetic Mouse Model of Insulin Resistance by Ghoshal, Kakali, Li, Xiyue, Peng, Dungeng, Falck, John R, Anugu, Raghunath Reddy, Chiusa, Manuel, Stafford, John M, Wasserman, David H, Zent, Roy, Luther, James M, Pozzi, Ambra

“…We previously showed that global deletion of the cytochrome P450 epoxygenase , a major epoxyeicosatrienoic acid (EET) producing enzyme in mice, leads to…”
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A novel sensor to estimate the prevalence of hypochlorous (HOCl) toxicity in individuals with type 2 diabetes and dyslipidemia by Ghoshal, Kakali, Das, Sangita, Aich, Krishnendu, Goswami, Shyamaprosad, Chowdhury, Subhankar, Bhattacharyya, Maitree

“…Oxidative stress is common in type 2 diabetes. It is characterised by increased levels of reactive oxygen species (ROS), of which hypochlorous acid (HOCl) is…”
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A Triphenyl Amine-Based Solvatofluorochromic Dye for the Selective and Ratiometric Sensing of OCl− in Human Blood Cells by Goswami, Shyamaprosad, Aich, Krishnendu, Das, Sangita, Pakhira, Bholanath, Ghoshal, Kakali, Quah, Ching Kheng, Bhattacharyya, Maitree, Fun, Hoong-Kun, Sarkar, Sabyasachi

“…A new visible‐light‐excitable fluorescence ratiometric probe for OCl− has been developed based on a triphenylamine‐diamiomaleonitrile (TAM) moiety. The…”
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Treatment of Primary Aldosteronism Increases Plasma Epoxyeicosatrienoic Acids by Luther, James M., Wei, Dawei S., Ghoshal, Kakali, Peng, Dungeng, Adler, Gail K., Turcu, Adina F., Nian, Hui, Yu, Chang, Solorzano, Carmen C., Pozzi, Ambra, Brown, Nancy J.

“…Epoxyeicosatrienoic acids (EETs) are lipid signaling molecules formed from arachidonic acid by the action of CYP450s. EETs cause vasodilation, exert…”
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The soluble epoxide hydrolase inhibitor GSK2256294 decreases the proportion of adipose pro-inflammatory T cells by Mashayekhi, Mona, Wanjalla, Celestine N., Warren, Christian M., Simmons, Joshua D., Ghoshal, Kakali, Pilkinton, Mark, Bailin, Samuel S., Gabriel, Curtis L., Pozzi, Ambra, Koethe, John R., Brown, Nancy J., Kalams, Spyros A., Luther, J. Matthew

“…•sEH inhibition decreases adipose tissue IFNγ-producing T helper cells and secreted TNFα.•sEH inhibition does not affect adipose tissue IL-17A…”
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EET Analog Treatment Improves Insulin Signaling in a Genetic Mouse Model of Insulin Resistance by Ghoshal, Kakali, Li, Xiyue, Peng, Dungeng, Falck, John R, Anugu, Raghunath Reddy, Chiusa, Manuel, Stafford, John M, Wasserman, David H, Zent, Roy, Luther, James M, Pozzi, Ambra

“…We previously showed that global deletion of the cytochrome P450 epoxygenase Cyp2c44, a major epoxyeicosatrienoic acid (EET) producing enzyme in mice, leads to…”
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Detection of HSO 3 - : A Rapid Colorimetric and Fluorimetric Selective Sensor for Detecting Biological SO 2 in Food and Living Cells by Paul, Sima, Ghoshal, Kakali, Bhattacharyya, Maitree, Maiti, Dilip K

“…A rapid fluorescent probe based on the conjugate of chromone and benzothiazole moiety was presented, which could selectively respond to HSO over other common…”
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