Search Results - "Ghosh, Sankar"

Understanding the Holobiont: How Microbial Metabolites Affect Human Health and Shape the Immune System by Postler, Thomas Siegmund, Ghosh, Sankar

“…The human gastrointestinal tract is populated by a diverse, highly mutualistic microbial flora, which is known as the microbiome. Disruptions to the microbiome…”
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Molecular mechanisms of innate memory and tolerance to LPS by Seeley, John J., Ghosh, Sankar

“…LPS is a potent trigger of macrophage‐mediated inflammation. However, prolonged exposure to LPS induces a state of tolerance that reprograms the inflammatory…”
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One step synthesis of C-dots by microwave mediated caramelization of poly(ethylene glycol) by Jaiswal, Amit, Ghosh, Siddhartha Sankar, Chattopadhyay, Arun

“…A rapid, simple and one step microwave mediated method for synthesizing C-dots using poly(ethylene glycol) (PEG) as a precursor and passivating agent is…”
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Disease-Associated SNPs in Inflammation-Related lncRNAs by Castellanos-Rubio, Ainara, Ghosh, Sankar

“…Immune-mediated diseases, such as celiac disease, type 1 diabetes or multiple sclerosis, are a clinically heterogeneous group of diseases that share many key…”
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Green Fluorescent Protein-Expressing Escherichia coli as a Model System for Investigating the Antimicrobial Activities of Silver Nanoparticles by GOGOI, Sonit Kumar, GOPINATH, P., PAUL, Anumita, RAMESH, A., GHOSH, Siddhartha Sankar, CHATTOPADHYAY, Arun

“…Recombinant Escherichia coli (E. coli) bacteria expressing green fluorescent protein (GFP) was used as a model system to investigate the antimicrobial…”
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Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism by Postler, Thomas S., Peng, Vincent, Bhatt, Dev M., Ghosh, Sankar

“…Metformin is a first-line drug in the treatment of type-2 diabetes mellitus (T2DM). In addition to its antigluconeogenic and insulin-sensitizing properties,…”
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Promoter Hypermethylation Profiling Identifies Subtypes of Head and Neck Cancer with Distinct Viral, Environmental, Genetic and Survival Characteristics by Choudhury, Javed Hussain, Ghosh, Sankar Kumar

“…Epigenetic and genetic alteration plays a major role to the development of head and neck squamous cell carcinoma (HNSCC). Consumption of tobacco…”
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Identification and re-evaluation of freshwater catfishes through DNA barcoding by Bhattacharjee, Maloyjo J, Laskar, Boni A, Dhar, Bishal, Ghosh, Sankar K

“…Catfishes are globally demanded as human food, angling sport and aquariums keeping thus are highly exploited all over the world. North-East India possess high…”
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Molecular Epidemiology of Amoebiasis: A Cross-Sectional Study among North East Indian Population by Nath, Joyobrato, Ghosh, Sankar Kumar, Singha, Baby, Paul, Jaishree

“…Epidemiological studies carried out using culture or microscopy in most of the amoebiasis endemic developing countries, yielded confusing results since none of…”
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Recognition and signaling by toll-like receptors by West, A Phillip, Koblansky, Anna Alicia, Ghosh, Sankar

“…Toll-like receptors (TLRs) are transmembrane proteins that detect invading pathogens by binding conserved, microbially derived molecules and that induce…”
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κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis by Beel, Stephanie, Kolloch, Lina, Apken, Lisa H., Jürgens, Lara, Bolle, Andrea, Sudhof, Nadine, Ghosh, Sankar, Wardelmann, Eva, Meisterernst, Michael, Steinestel, Konrad, Oeckinghaus, Andrea

“…Pancreatic ductal adenocarcinoma (PDAC) is associated with high mortality and therapy resistance. Here, we show that low expression of κB-Ras GTPases is…”
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Epigenetic, genetic and environmental interactions in esophageal squamous cell carcinoma from northeast India by Talukdar, Fazlur Rahman, Ghosh, Sankar Kumar, Laskar, Ruhina Shirin, Mondal, Rosy

“…Esophageal squamous cell carcinoma (ESCC) develops as a result of complex epigenetic, genetic and environmental interactions. Epigenetic changes like, promoter…”
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Recognition of Profilin by Toll-like Receptor 12 Is Critical for Host Resistance to Toxoplasma gondii by Koblansky, A. Alicia, Jankovic, Dragana, Oh, Hyunju, Hieny, Sara, Sungnak, Waradon, Mathur, Ramkumar, Hayden, Matthew S., Akira, Shizuo, Sher, Alan, Ghosh, Sankar

“…Toll-like receptor 11 (TLR11) recognizes T. gondii profilin (TgPRF) and is required for interleukin-12 production and induction of immune responses that limit…”
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Whole exome sequencing identifies the potential role of genes involved in p53 pathway in Nasopharyngeal Carcinoma from Northeast India by Laskar, Shaheen, Das, Raima, Kundu, Sharbadeb, Saha, Amrita, Nandi, Nilashis, Choudhury, Yashmin, Kumar Ghosh, Sankar

“…•p53 pathway harborsthe maximum percentage of clinically deleterious variants.•rs138941861 in STEAP3 gene was the most deleterious exonic unique-case…”
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The Alternative NF-κB Pathway in Regulatory T Cell Homeostasis and Suppressive Function by Grinberg-Bleyer, Yenkel, Caron, Rachel, Seeley, John J, De Silva, Nilushi S, Schindler, Christian W, Hayden, Matthew S, Klein, Ulf, Ghosh, Sankar

“…CD4 Foxp3 regulatory T cells (Tregs) are essential regulators of immune responses. Perturbation of Treg homeostasis or function can lead to uncontrolled…”
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An Essential Role for ECSIT in Mitochondrial Complex I Assembly and Mitophagy in Macrophages by Carneiro, Flávia R.G., Lepelley, Alice, Seeley, John J., Hayden, Matthew S., Ghosh, Sankar

“…ECSIT is a mitochondrial complex I (CI)-associated protein that has been shown to regulate the production of mitochondrial reactive oxygen species (mROS)…”
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Toll-Like Receptor 11 (TLR11) Interacts with Flagellin and Profilin through Disparate Mechanisms by Hatai, Hirotsugu, Lepelley, Alice, Zeng, Wangyong, Hayden, Matthew S, Ghosh, Sankar

“…Toll-like receptors (TLRs) are innate immune receptors that sense a variety of pathogen-associated molecular patterns (PAMPs) by interacting with them and…”
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The species dilemma of Northeast Indian Mahseer (Actinopterygii: Cyprinidae): DNA barcoding in clarifying the riddle by Laskar, Boni A, Bhattacharjee, Maloyjo J, Dhar, Bishal, Mahadani, Pradosh, Kundu, Shantanu, Ghosh, Sankar K

“…The taxonomic validity of Northeast Indian endemic Mahseer species, Tor progeneius and Neolissochilus hexastichus, has been argued repeatedly. This is mainly…”
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Role of DNA barcoding in marine biodiversity assessment and conservation: An update by Trivedi, Subrata, Aloufi, Abdulhadi A., Ansari, Abid A., Ghosh, Sankar K.

“…More than two third area of our planet is covered by oceans and assessment of marine biodiversity is a challenging task. With the increasing global population,…”
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Negative Regulation of Toll-like Receptor-mediated Signaling by Tollip by Zhang, Guolong, Ghosh, Sankar

“…Toll-like receptor (TLR)-mediated recognition of pathogens represents one of the most important mechanisms of innate immunity and disease resistance. The…”
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